18/06/2026
You're not a lightweight now. Your chemistry changed. π·
One glass of wine. And then β the flushed face, the racing heart, wide awake at 2am, a headache by morning. And you blamed yourself.
Here's what actually happened: oestrogen has two jobs with histamine. It tells your body to RELEASE it, and it powers DAO, the enzyme that CLEARS it. In perimenopause, oestrogen swings β so histamine pools. Wine just pours more on top.
That's why it all turns on you at once: red wine, aged cheese, cured meats, tomatoes, spinach, avocado, leftovers, anything fermented⦠and it stacks on hayfever season.
You are not fragile. Your chemistry changed.
π Save this for the night you ask "why?" β then send it to the friend who keeps saying wine doesn't agree with her anymore.
Follow for the perimenopause stuff no one explained. π
(Education, not medical advice β always chat to your GP about your own symptoms.)