18/01/2026
Maltofer (Iron polymaltose complex) is an iron supplement used to treat and prevent iron deficiency in adults and adolescents, particularly when ferrous iron supplements are not tolerated. It is known for having fewer gastrointestinal side effects compared to traditional ferrous iron salts.
Here is a summary of the literature and prescribing information for Maltofer:
1. Indications and Usage
Iron Deficiency Anemia: Treatment of iron deficiency anemia in adults, adolescents, and children (over 12 years).
Prevention: Prophylactic therapy to cover high-risk individuals, including pregnancy, lactation, and vegetarianism.
Intolerance: Suitable for patients who cannot tolerate traditional ferrous iron supplements due to constipation or nausea.
2. Dosage and Administration (Oral)
Adults/Adolescents: Generally 1 to 3 tablets (100mg elemental iron each) per day.
Administration: Can be taken with or without food, as absorption is not inhibited by food (unlike ferrous salts).
Duration: Treatment may take a few weeks to start working and 3-6 months for full iron correction.
3. Side Effects
Maltofer is designed to be well-tolerated, but common side effects (if any) are usually mild.
Common: Nausea, constipation, diarrhea, abdominal pain, headache, dizziness, and discoloured faeces.
Uncommon/Rare: Hypersensitivity reactions, rash, vomiting, pruritus, and fever.
4. Precautions and Contraindications
Contraindications: Known hypersensitivity to Iron(III)-hydroxide polymaltose complex.
Contraindications: Anemia not caused by iron deficiency (e.g., hemolytic anemia).
Warning: It may mask vitamin B12 deficiency; check vitamin B12 levels prior to long-term treatment.
Overdose: Unlikely due to the low toxicity of the complex, but excessive intake can lead to iron accumulation (hemosiderosis).
5. Pharmacology
Active Ingredient: Iron(III)-hydroxide polymaltose complex (IPC).
Mechanism: Iron polymaltose is a stable complex that releases iron in a controlled manner, reducing the likel