09/01/2026
Perimenopause can affect mood, sleep, muscle function, and joint comfort — largely due to fluctuating oestrogen levels and increased nervous system demand.
Magnesium is one of the most well-researched minerals for women during this transition. In particular, magnesium glycinate is recognised for its high bioavailability and superior tolerability, especially for women experiencing stress, hormonal shifts, and digestive sensitivity.
Magnesium plays a critical role in:
• Nervous system regulation and mood support
• Muscle relaxation and reduction of cramps
• Joint comfort and inflammatory balance
• Sleep quality and relaxation pathways
When bound to glycine, an inhibitory amino acid, magnesium glycinate has been shown to support calming neurotransmitter activity and improve neuromuscular function — making it especially beneficial during perimenopause when sleep disturbance, muscle tension, and emotional reactivity are common.
As oestrogen levels fluctuate, magnesium requirements often increase, and deficiency has been associated with increased muscle pain, low mood, and sleep disruption.
Perimenopause isn’t something to “push through.”
It’s a phase that deserves targeted, science-backed nutritional support.
References:
• de Baaij JHF et al. Magnesium in Man: Implications for Health and Disease. Physiol Rev. 2015.
• Barbagallo M, Dominguez LJ. Magnesium and Aging. Curr Pharm Des. 2010.
• Nielsen FH. Magnesium deficiency and increased inflammation. Curr Opin Clin Nutr Metab Care. 2014.
• Abbasi B et al. The effect of magnesium supplementation on insomnia. J Res Med Sci. 2012.
