13/04/2025
Did you know, that later this year,
We will be able to offer the NHS New Nedicine Service (NMS) for patients started on antidepressants.
Don't worry, our pharmacist is happy to support you.
Here are top 5 tips:
1. Be Patient – Antidepressants Take Time to Work
Advice: “You may not feel better right away. Antidepressants usually take 2 to 4 weeks to start working, and full effects may take 6 to 8 weeks. Keep taking it even if you don’t feel immediate changes.”
Why it matters: Many patients stop their medication early, thinking it’s ineffective. Reassurance and proper expectations improve adherence.
2. Take It Consistently, at the Same Time Each Day
Advice: “Take your medication exactly as prescribed, ideally at the same time each day. Missing doses can reduce effectiveness and increase side effects or risk of relapse.”
Why it matters: Antidepressants work best with stable blood levels. Inconsistent dosing increases risk of withdrawal symptoms or reduced efficacy.
3. Watch for Side Effects – But Don’t Panic
Advice: “You may experience side effects like nausea, sleep changes, or headaches in the first week or two – these usually improve. Let us know if anything feels severe or persists.”
Why it matters: Side effects are often the biggest barrier to adherence. Preemptively counseling patients increases tolerance and reduces drop-out.
4. Avoid Alcohol and Be Cautious with Other Medications
Advice: “Avoid alcohol, and let your pharmacist know about any other medications or supplements you’re taking – some can interact with your antidepressant.”
Why it matters: Many antidepressants (especially SSRIs, SNRIs, TCAs) have important drug-drug interactions, and alcohol can worsen side effects or depression itself.
5. Don’t Stop Abruptly – Tapering Is Crucial
Advice: “If you ever want to stop the medication, don’t stop suddenly. Talk to your pharmacist/GP so we can taper it slowly and avoid withdrawal symptoms.”
Why it matters: Discontinuation syndrome can cause dizziness, insomnia, flu-like symptoms, and rebound depression. Gradual tapering minimise this risk.
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