Hystelica

Hystelica We are a community built to understand women’s biology for safe and effective psychedelic use

We're proud to announce that Hystelica research assistant Aline Frick will be presenting at ICPR 2026 — sharing propriet...
27/04/2026

We're proud to announce that Hystelica research assistant Aline Frick will be presenting at ICPR 2026 — sharing proprietary Hystelica data on psychedelic use during menopause.
Menopause is one of the most under-researched windows in women's health — and one where psychedelic experience, symptom burden and therapeutic potential all deserve far closer attention. Aline will be walking through what our data is telling us, and what it means for the next chapter of women-centred psychedelic research.
A first-of-its-kind dataset, presented on Europe's biggest psychedelic research stage.
ICPR 2026
4–6 June 2026 · Haarlem, Netherlands
Hosted by the OPEN Foundation
Tickets + full programme: https://www.icpr-conference.com/tickets

Hystelica is the first dedicated platform advancing psychedelic research, education, and clinical innovation for women.T...
24/04/2026

Hystelica is the first dedicated platform advancing psychedelic research, education, and clinical innovation for women.
The problem we're here to solve: women's bodies have been systematically excluded from biomedical research for decades. In psychedelics — a field with extraordinary therapeutic potential for conditions that disproportionately affect women (depression, PTSD, chronic pain, eating disorders, perimenopause) — the pattern is repeating. Women make up the majority of participants in psychedelic-assisted therapy, yet almost none of the clinical trials are designed with their biology in mind.
We're changing that.
What we do:
– Design and lead women-specific clinical research, including work on PMDD, menopause, and chronic pelvic pain
– Develop evidence-based education for clinicians, researchers, and women navigating their own health
– Host events and panels that bring together the leading voices in women's health, neuroscience, and psychedelic medicine
– Advocate for inclusion, s*x-based analysis, and precision care as the standard — not the exception
Inclusion requires diligence. We're doing the work.
Follow along, and join the conversation 🌿

Endometriosis rarely comes alone.New research using unsupervised clustering has identified distinct comorbidity patterns...
22/04/2026

Endometriosis rarely comes alone.
New research using unsupervised clustering has identified distinct comorbidity patterns in people with endometriosis - grouping conditions like autoimmune disease, chronic pain (including fibromyalgia), anxiety and depression, and pregnancy complications into recognisable clusters.
This confirms what so many patients have long described: endometriosis is rarely a single condition. It travels with others.
Identifying these subtypes opens the door to more personalised care — matching therapies to each person's pattern of pain, hormones, and immune function.
This is where endometriosis care needs to go.
Khan et al. (2025). "Comorbidity analysis and clustering of endometriosis patients using electronic health records." Cell Reports Medicine.

Women's biology deserves its own conversation in psychedelic science.Thrilled to share that our founder Dr Grace Blest-H...
20/04/2026

Women's biology deserves its own conversation in psychedelic science.
Thrilled to share that our founder Dr Grace Blest-Hopley will be presenting and joining the panel on women's biology and psychedelics at ICPR 2026 — Europe's premier psychedelic research conference.
She'll be in conversation with an incredible line-up:
Helena Aicher · Eline Haijen-Bongers · Natasha Mason · Kim Kuypers
Together they'll be exploring how s*x, hormones and the nuances of female physiology shape psychedelic experience, response and therapeutic outcomes — a conversation that's long overdue in the field.
ICPR 2026
4–6 June 2026 · Haarlem, Netherlands
Hosted by the OPEN Foundation
Tickets + full programme: https://www.icpr-conference.com/tickets

Speaking at Cannabis Europa London 2026 🌿Barbican · 27th May · 11:30amThe panel is about cannabis and women's health. Bu...
17/04/2026

Speaking at Cannabis Europa London 2026 🌿

Barbican · 27th May · 11:30am

The panel is about cannabis and women's health. But the question I keep coming back to is simpler than that: why don't we have the data?

Hormones change how drugs work in the body. Oestrogen and progesterone interact with the endocannabinoid system in ways that are measurable - and that shift across the menstrual cycle, perimenopause, menopause. But most cannabis research doesn't even record the s*x of participants, let alone their hormonal status.

We can't answer whether cannabis-based treatments work well for women until we start asking the right questions about women's biology.

That's what I'll be bringing to this conversation.

Anorexia nervosa has one of the highest mortality rates of any psychiatric condition - and it disproportionately affects...
15/04/2026

Anorexia nervosa has one of the highest mortality rates of any psychiatric condition - and it disproportionately affects girls and women.

So why does so much of the research still not reflect the complexity of female biology?

A recent experimental study explored how psilocybin affects social behaviour and inflammation in female mice in an anorexia-like state. The findings weren't simple. Psilocybin's effects were subtle, variable, and context-dependent — shaped by metabolism, physiology, and biological state.

In short: it worked differently depending on the body.

This matters. Because if we want treatments that actually work for women, we need research that reflects real bodies, real conditions, and real complexity.

Psilocybin is not one fixed experience. Neither are women.

Is women's anger making them sick? 🔥80% of autoimmune disorders affect women — yet many live with chronic pain while bei...
09/04/2026

Is women's anger making them sick? 🔥
80% of autoimmune disorders affect women — yet many live with chronic pain while being disbelieved, dismissed, or gaslit in medical settings.
What happens to the body when anger and rage are chronically suppressed?
The research doesn't yet show a clear causal link between suppressed anger and autoimmune disease - but chronic stress, invalidation, and emotional suppression may disrupt immune and inflammatory regulation.
Listening to women's experiences, including their anger, is not soft science. It's essential to understanding how conditions like autoimmune disease develop.
Read our blog about on this topic on the Hystelica Website - links in bio -

What if psychedelics could transform the way we experience perimenopause and menopause? 🍄On April 30th, 6–8pm BST, we're...
08/04/2026

What if psychedelics could transform the way we experience perimenopause and menopause? 🍄
On April 30th, 6–8pm BST, we're bringing together three leading women in psychedelic science for a live webinar exploring the cutting edge of research at the intersection of psychedelics and women's hormonal health.
🔬 Dr Grace Blest-Hopley - neuroscientist and founder of Hystelica
🧠 Dr Lydia French - Oxford-trained psychotherapist and psychedelic research consultant
🌿 Ana Jiménez- ecosomatic women's health practitioner and founder of Amawa Academy
This is the conversation that's been missing from both the menopause and psychedelic spaces. Come and be part of it.
🔗 Register via the link in bio.

What if psychedelics could transform the way we experience perimenopause and menopause? 🍄On April 30th, 6–8pm BST, we're...
07/04/2026

What if psychedelics could transform the way we experience perimenopause and menopause? 🍄
On April 30th, 6–8pm BST, we're bringing together three leading women in psychedelic science for a live webinar exploring the cutting edge of research at the intersection of psychedelics and women's hormonal health.
🔬 Dr Grace Blest-Hopley - neuroscientist and founder of Hystelica
🧠 Dr Lydia French - Oxford-trained psychotherapist and psychedelic research consultant
🌿 Ana Jiménez- ecosomatic women's health practitioner and founder of Amawa Academy
This is the conversation that's been missing from both the menopause and psychedelic spaces. Come and be part of it.
🔗 Register via the link in bio.


Ready for the next post!Sonnet 4.6

Hormones shape how drugs work. So why are women's hormonal states still under-measured in research? 🔬A new AI model call...
31/03/2026

Hormones shape how drugs work. So why are women's hormonal states still under-measured in research? 🔬

A new AI model called HormoNet is changing that — predicting hormone-drug interactions (including psychedelics) before trials begin.
This is the future of medicine: designed around your biology, not averaged data. 🌸

What did women in the Amazon know about psychedelics and the female body — long before any clinical trial asked the ques...
28/03/2026

What did women in the Amazon know about psychedelics and the female body — long before any clinical trial asked the question?

We sat down with Dr. Paulina Valamiel Lopes, sociologist, ayahuasqueira, and co-founder of Hijas del Sur, to find out.

Paulina spent a decade inside the Santo Daime tradition — interviewing 30 women across 12+ countries about how they navigate ayahuasca across their menstrual cycle, pregnancy, childbirth, and menopause. What she found is extraordinary: women from the UK to Japan to Brazil, with no contact with each other, arriving at the same embodied practices independently. No clinical guidance. No research papers. Just bodies, attention, and generations of oral knowledge.
This is the kind of research Hystelica exists for.

Head to the blog to read the full conversation — link in bio. 🌿

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