16/07/2024
Dr. Joshua’s allergy inspired him for a new invention?
What? Dr. J, what more do you want? We thought the road ahead was clear. We had a potent stem cell secretome for skin regeneration and the advanced Herbal-Derived Transdermal Delivery System (TDS).
Sometimes no..many times it is hard to understand the obsessiveness or pursuit of perfection (if you put in a good way) of stubborn scientists. Dr. J felt something was still lacking. Despite our tight timeline, he insisted, "I will try to get more funding, and if we need to delay the launch, so be it. If I cannot believe in our product's efficacy, I cannot release it to the world." Dr. J suspected some stem cell secretome components, particularly proteins, were still too large to pass through the skin barrier even with TDS. "We need something physical to help," he said.
OMG, really wanted to throw something sharp at him. Someone said ‘have you heard about something called spicule?’ spicules; tiny, needle-like structures found in certain seaweeds used in cosmetics for physical peeling. It grabbed out attention and we called immediately a few companies to request some samples. Of course, very curious Dr. J volunteered for testing. He said ‘it really stings.’ However, in a few hours later sting was not a problem at all. Dr. J developed an allergic reaction. His skin was red and looked like a shingles. ‘It could be safe to majority but If even one person out of a thousand has an allergic reaction, we cannot use it.’ Spicules, it turned out, are not soluble and must be washed off, or they can cause allergies.
What if there is something sharp soluble micro-particles so easy to absorb or wash? We discovered the field of microneedles, initially developed for needle-phobic patients. This technology had evolved into soluble microneedles. After consulting with microneedle patch manufacturers, our researchers developed a method to produce soluble particles with sharp edges, which we called micro-spears. These were gentler than spicules but still effective, providing a physical path for stem cell secretome. Finally, Dr. J was confident.
Now, it was the designer’s turn.