Mandalay Health and Research Center

Mandalay Health and Research Center MHRC is a professional institution dedicated to advancing health and research excellence in Myanmar.

17/04/2026
12/04/2026

Analysis of real-world pharmacovigilance data shows that GLP-1s demonstrate distinct adverse event patterns across indications, primarily related to metabolic, nutritional, gastrointestinal, and psychiatric disorders, with different profiles observed across treatments.

“As millions of patients are taking GLP-1s for weight control and obesity treatment worldwide, clinicians should be vigilant in monitoring for unanticipated long-term adverse effects,” the authors of the study wrote. More on the study: https://mdsc.pe/4viMPNG

12/04/2026

1.4 billion people live with hypertension.

Hypertension is the number one risk factor for:
‼️ Heart attack
‼️ Stroke

and can lead to:
‼️ Chronic kidney disease
‼️ Dementia

Get your blood pressure checked today!

07/04/2026

📣 Applications are now open for the 2026 LeadNext: Ambassadors for a Global Future fellowship!

Ready to create lasting impact across borders and sectors?

Step into global leadership with LeadNext—TAF’s flagship youth fellowship program equipping emerging leaders (ages 18-25) from across Asia-Pacific and the United States with the skills, networks, and global perspective to turn ideas into action for the 21st century.

What the fellowship offers:
✅ Virtual leadership training and expert-led masterclasses
✅ One-on-one mentorship
✅ In-person participation in the Global Leaders Summit in the United States

Don’t miss this opportunity to grow, connect, and lead.

📅 Fellowship period: June-September 2026
🗓️ Applications close on May 5, 2026
🔗 Learn more and apply: https://asiafoundation.org/call-for-applications-2026-leadnext-ambassadors-for-a-global-future/

Chronic Hepatitis B
06/04/2026

Chronic Hepatitis B

Individualising endpoints in chronic HBV treatment: HBsAg loss and beyond

There are many new compounds in development for the treatment of chronic hepatitis B (CHB). Although major on-treatment declines in hepatitis B surface antigen (HBsAg) can be achieved with some of these drugs, achieving sustained post-treatment HBsAg loss with undetectable HBV DNA (functional cure) remains challenging, particularly in patients with high pretreatment HBsAg levels. Interestingly, a substantial proportion of patients in these trials who did not achieve HBsAg loss did maintain low HBsAg levels after withdrawal of study treatments. Based on data from natural history studies and studies on finite treatment with currently available agents, off-treatment sustained low HBsAg levels with low or undetectable HBV DNA levels (referred to as partial cure) is associated with excellent virological and clinical outcomes. In this expert opinion article, we argue that it is important to shift focus from HBsAg loss as the sole endpoint of HBV trials to a more individualised assessment of response that also considers partial cure (defined as off-treatment sustained low HBsAg with undetectable HBV DNA, potentially combined with other biomarkers) as a favourable treatment outcome. Such an approach could increase the number of patients considered responders and, in doing so, potentially extend eligibility for novel therapies to more patients with CHB who may derive significant clinical benefit.

Expert Opinion by Milan Sonneveld and Harry Janssen

here: https://www.journal-of-hepatology.eu/article/S0168-8278(25)02724-2/fulltext

EASL - The Home of Hepatology

04/04/2026

How are vaccines evaluated after approval?

JAMA Statistical Editor Roger Lewis, MD, PhD, and Natalie Dean, PhD, explain the test-negative study design, highlighting its role in analyzing effectiveness and minimizing bias in observational studies.

🎧 Listen now: https://ja.ma/4tvbVaq

01/04/2026

ภาควิชาระบาดวิทยาคลินิกเเละชีวสถิติ คณะเเพทยศาสตร์โรงพยาบาลรามาธิบดี มหาวิทยาลัยมหิดล เปิดรับสมัครนักศึกษาใหม่ประจำปีการศึกษา 2569 ผู้สนใจสามารถส่งใบสมัครพร้อมเอกสารที่เกี่ยวข้องผ่าน QR Code ดังเเนบ ปิดรับสมัครรอบที่สองตั้งเเต่วันนี้ถึงวันที่ 31 พฤษภาคม 2569 (รอบสุดท้าย)
ลิ้งสมัคร: https://graduate.mahidol.ac.th/admission-apply/

Department of Clinical Epidemiology and Biostatistics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, accepts new applicants to study our programs for the academic year 2026. For those who want to submit their applications along with the required documents, please scan the QR Code below by 31 May 2026 (Final round).
Application's link: https://graduate.mahidol.ac.th/admission-apply/

31/03/2026

Statistical Hypothesis Testing
This infographic, titled "How to Understand Statistical Hypothesis Testing," provides a comprehensive visual breakdown of the core concepts used in inferential statistics. It follows a clean, modular design with color-coded sections to help students and professionals navigate the complexities of making data-driven decisions.
Key Sections:
* Defining Hypothesis Testing: Explains the transition from population parameters to sample statistics and the conceptual framework of using an estimator to reach a decision.
* Key Test Components: Breaks down the Null (H_0) and Alternative (H_1) hypotheses, the \alpha-level (significance), and visualizes the rejection vs. acceptance regions on a distribution curve.
* Understanding Errors: Features a "Hypothesis Testing Error Matrix" that clarifies the difference between Type I Errors (False Positives) and Type II Errors (False Negatives), as well as the concept of Statistical Power.
* Decision Rules & p-values: Contrasts large vs. small p-values, showing exactly how they relate to the critical region and the decision to either "Reject" or "Fail to Reject" the null hypothesis.
* One-Tailed vs. Two-Tailed Tests: Visualizes the differences in directional testing, illustrating Left-Tail, Right-Tail, and Two-Tailed distributions.
* Application Best Practices: Offers practical advice, such as checking test assumptions, reporting effect sizes, and the importance of sample size

31/03/2026

Stay safe Cambodia! 😷🐔🇰🇭

The Health Ministry of Cambodia reports its third human H5N1 case in a 3-year-old boy. Health officials urge everyone to avoid contact with sick or dead birds and report any unusual poultry deaths immediately.

31/03/2026

🎓 Prospect Burma Online Scholarship is Now Open!

The deadline to apply is 31st May 2026 (10:00 PM Myanmar time). Applications submitted after this deadline will be ineligible.

👉 Apply Here:
https://prospectburma.my.site.com/onlineapplications/s/online-education-application

Prospect Burma will also be organizing information sessions and student experience-sharing sessions in the coming weeks. These sessions will give you the opportunity to ask questions and learn more about the application process.

To learn more about the scholarship and the application process, please read the Scholarship Guidance Note carefully: https://students.prospectburma.org/online-scholarships/

Apply now and don’t miss this opportunity!

Address

No. 20, 41 X 42 Streets & 81 X 82 Streets
Mandalay
05031

Opening Hours

Monday 17:00 - 21:00
Tuesday 17:00 - 21:00
Wednesday 17:00 - 21:00
Thursday 05:00 - 21:00
Friday 17:00 - 21:00
Saturday 17:00 - 21:00
Sunday 09:30 - 13:00

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