01/09/2026
This case illustrates malignant central airway obstruction (MCAO) that progressed significantly over a two-month period following a delay in referral. The patient subsequently developed worsening breathlessness and exertional dyspnoea, eventually becoming oxygen-dependent. CT imaging showed extensive tumour involvement of the right upper and middle lobes, with only the right lower lobe remaining aerated.
Following rigid bronchoscopy with tumour debulking and airway stenting, patency of the RB7–10 segments was successfully restored and maintained. The patient experienced marked symptomatic improvement and was successfully weaned off supplemental oxygen within four days.
This case further highlights the important role of rigid bronchoscopy and airway stenting as a bridging therapy in selected patients with malignant central airway obstruction. Timely restoration of airway patency can provide rapid symptomatic relief, improve functional status and ECOG performance status, and potentially enable patients to proceed to definitive oncological treatment.