Miguel & Donald Pharmacy & Stores Limited

15/05/2026

HBV treatment. As of May 2026, the quest for a functional cure has moved from “hopeful research” into the active regulatory approval phase.
​The specific date you likely heard about—October 2026—is the official deadline for the FDA to decide on the first major functional cure candidate.
​1. The Frontrunner: GSK’s Bepirovirsen
​The biggest news right now is that GSK officially submitted its New Drug Application (NDA) for bepirovirsen in April 2026.
​Priority Review Status: The U.S. FDA has granted it “Priority Review,” which fast-tracks the process.
​The Decision Date: The FDA is expected to announce its decision by October 26, 2026.
​Stage: It has completed Phase 3 trials (B-Well 1 and B-Well 2), which showed that a significant number of patients achieved a functional cure—meaning they cleared the HBsAg surface antigen and maintained control of the virus after stopping treatment.
​2. Other Key Players in the Pipeline
​While GSK is the closest to the finish line, other “combination” therapies are in the final stretch:
​Vir Biotechnology (VIR-2218 + VIR-3434): Currently in advanced Phase 2b/3 trials. They are seeing very high rates of surface antigen loss by combining an siRNA (which stops the virus) with a potent antibody.
​Janssen/Arrowhead (JNJ-3989): Also in the late stages of testing. Their focus is on “silencing” the viral DNA to allow the immune system to recover.
​3. What Happens in October 2026?
​If the FDA approves bepirovirsen on its October deadline:
​Manufacturing & Distribution: GSK has already signed major deals (including a massive launch deal in China just this month) to ensure the drug can be produced and shipped quickly.
​Market Availability: While it might not be in every local pharmacy on November 1st, it will likely be available through specialists and major hospitals by late 2026 or early 2027.

09/05/2026

Ever faithful

10/03/2026

God is great!

06/02/2025

06/02/2025

Health is wealth 🙏

18/09/2024

Adding apple cider vinegar to your green tea can offer several health benefits, as both are known for their individual properties. Here's a look at what combining them might do for you:

1. Boosts Digestion:

Apple cider vinegar is known for promoting healthy digestion due to its acetic acid content. Green tea contains catechins that also aid digestion and metabolism. Together, they can improve gut health and aid in the digestion process.

2. Supports Weight Management:

Both green tea and apple cider vinegar are popular for supporting weight loss. Green tea boosts metabolism, and apple cider vinegar helps control blood sugar and reduces appetite. When combined, they can enhance these effects.

3. Rich in Antioxidants:

Green tea is packed with antioxidants, especially catechins like EGCG (epigallocatechin gallate), which support overall health and reduce inflammation. Apple cider vinegar also has antioxidant properties, making this combination beneficial for fighting free radicals.

4. Helps Regulate Blood Sugar:

Apple cider vinegar can help regulate blood sugar levels, especially after meals, while green tea supports stable energy levels. This combination can be especially beneficial if you're looking to manage blood sugar.

5. Boosts Immunity:

Green tea and apple cider vinegar both have immune-boosting properties. Green tea has anti-inflammatory and antiviral effects, and apple cider vinegar can help fight harmful bacteria.

6. Improves Skin Health:

The antioxidants and anti-inflammatory compounds found in green tea, combined with the potential detoxifying effects of apple cider vinegar, may promote clearer skin and reduce inflammation.

Precautions:

Acidity: Apple cider vinegar is highly acidic, so be cautious with the amount you add to avoid stomach irritation or damage to tooth enamel. Usually, 1-2 teaspoons in a cup of tea is sufficient.

Timing: Drinking this combination on an empty stomach could cause discomfort for some, so it’s best to see how your body responds.

Moderation: Both apple cider vinegar and green tea should be consumed in moderation to avoid any potential side effects, such as digestive upset or over-acidity.

Overall, combining apple cider vinegar with green tea can be a healthy habit, as long as it's done in moderation and you are mindful of how your body reacts.

16/09/2023

Answer (1 of 6): Onions and garlic have good anti-bacterial properties that help prevent infections and promote healing. They are known for their ability to purify the blood. Lemon juice contains citric acid, which is a natural acid that aids the digestion and absorption of calcium. lemons also ...

04/02/2021

Honey have a taste of this honey....

29/12/2020

Great...

The medication, now the subject of 58 separate research projects, is aimed at ending a lifelong need for drugs to manage the viral liver infection.

26/08/2020

Faithful God bless our hustle...