09/06/2026
AKWA IBOM STATE MINISTRY OF HEALTH
Directorate of Public Health
Epidemiology Unit
EBOLA DISEASE (EBOD): PUBLIC HEALTH INFORMATION GUIDE
KEY FACTS
Ebola Disease (EBOD) is a severe and often fatal viral illness affecting humans.
Three viruses are known to cause major Ebola outbreaks: Ebola virus (EBOV), Sudan virus (SUDV), and Bundibugyo virus (BDBV)
The average case fatality rate is approximately 50%, although mortality rates have ranged from 25% to 90% during previous outbreaks.
Early detection, prompt treatment, intensive supportive care, and rehydration significantly improve survival rates.
Approved vaccines and treatments are currently available only for Ebola Virus Disease (EVD) caused by the Ebola virus.
Effective outbreak control relies on comprehensive interventions, including surveillance, contact tracing, infection prevention and control (IPC), laboratory diagnosis, safe burials, community engagement, and vaccination where applicable.
OVERVIEW
Ebola Disease (EBOD) is a rare but highly dangerous viral haemorrhagic fever that can cause severe illness and death in humans. The disease is caused by viruses belonging to the Orthoebolavirus genus of the Filoviridae family.
Six species of Orthoebolaviruses have been identified, with three responsible for major human outbreaks:
Ebola Virus (EBOV) – causes Ebola Virus Disease (EVD)
Sudan Virus (SUDV) – causes Sudan Virus Disease (SVD)
Bundibugyo Virus (BDBV) – causes Bundibugyo Virus Disease (BVD)
The disease was first identified in 1976 during simultaneous outbreaks in present-day South Sudan and the Democratic Republic of Congo. The outbreak in Congo occurred near the Ebola River, from which the disease derived its name.
Although licensed vaccines and therapeutic agents exist for Ebola Virus Disease, no approved vaccines or treatments currently exist for Sudan Virus Disease and Bundibugyo Virus Disease, though several promising candidates are under development.
MODE OF TRANSMISSION
Scientific evidence suggests that fruit bats of the Pteropodidae family serve as the natural reservoir hosts of Ebola viruses.
Animal-to-Human Transmission
Human infection may occur through direct contact with infected animals, including:
Fruit bats
Chimpanzees
Gorillas
Monkeys
Forest antelopes
Porcupines
Exposure to blood, secretions, organs, or bodily fluids of infected animals can result in transmission.
Human-to-Human Transmission
The virus spreads through direct contact with:
Blood of infected persons
Saliva
Sweat
Urine
Vomit
Faeces
Breast milk
Semen
Other body fluids
Transmission can also occur through contact with contaminated objects and surfaces such as:
Needles and syringes
Clothing
Bedding
Medical equipment
Importantly, individuals do not transmit Ebola before symptoms appear. However, infected persons remain contagious as long as the virus is present in their blood and body fluids.
Healthcare workers and caregivers are particularly vulnerable when infection prevention measures are not strictly followed.
Traditional burial practices involving direct contact with the body of deceased Ebola patients can also contribute significantly to disease transmission.
SIGNS AND SYMPTOMS
The incubation period ranges from 2 to 21 days, with an average of 8–10 days.
Symptoms often begin suddenly and may include:
Early Symptoms
High fever
Severe weakness and fatigue
Headache
Muscle and joint pains
Sore throat
General malaise
Progressive Symptoms
Vomiting
Diarrhoea
Abdominal pain
Loss of appetite
Difficulty swallowing
Skin rash
Difficulty breathing
Severe Symptoms
Impaired liver and kidney function
Confusion and altered mental state
Irritability and aggression
Internal and external bleeding
Bleeding manifestations may include:
Blood in vomit
Blood in stool
Bleeding from the nose
Bleeding gums
Vaginal bleeding
Bleeding from injection sites
Not all patients develop bleeding symptoms, and their absence does not rule out Ebola Disease.
CASE DEFINITION
Suspected Case
Any person presenting with sudden onset of fever and at least three of the following symptoms:
Headache
Fatigue
Loss of appetite
Muscle pain
Joint pain
Stomach pain
Difficulty swallowing
Vomiting
Difficulty breathing
Diarrhoea
Hiccups
AND having a history of:
Travel to an affected area; or
Contact with a confirmed or probable Ebola case; or
Participation in burial rites involving a suspected Ebola victim.
Probable Case
A deceased person with symptoms compatible with Ebola Disease who had an epidemiological link to a confirmed case but was not laboratory tested.
Confirmed Case
A suspected or probable case with laboratory confirmation of Ebola virus infection.
DIAGNOSIS
Clinical diagnosis can be challenging because Ebola symptoms resemble those of:
Malaria
Typhoid fever
Meningitis
Shigellosis
Lassa fever
Other viral haemorrhagic fevers
Confirmation requires specialized laboratory testing such as:
Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)
Antigen-capture detection tests
Antibody-capture ELISA
Virus isolation by cell culture
Specimens collected from suspected cases are highly infectious and must be handled under strict biosafety conditions using recommended triple packaging systems during transportation.
TREATMENT AND CLINICAL MANAGEMENT
There is currently no universally approved cure for all Ebola diseases. However, early supportive care greatly improves survival.
Recommended supportive care includes:
Oral or intravenous rehydration
Correction of electrolyte imbalance
Nutritional support
Oxygen therapy when necessary
Pain management
Treatment of co-infections such as malaria and bacterial infections
Monitoring and management of complications
For Ebola Virus Disease caused by the Ebola virus, WHO recommends treatment with monoclonal antibodies such as:
Ansuvimab (mAb114)
REGN-EB3 (Inmazeb)
These treatments have demonstrated improved survival outcomes when administered early.
VACCINATION
Approved Vaccines for Ebola Virus Disease
Ervebo® (Merck & Co.)
Zabdeno® and Mvabea® (Janssen Pharmaceutica)
Vaccination is primarily used during outbreak response and for protecting frontline healthcare workers and other high-risk populations.
Research and clinical trials are ongoing to develop vaccines for Sudan Virus Disease and Bundibugyo Virus Disease.
PREVENTION AND CONTROL MEASURES
Community participation remains the cornerstone of outbreak prevention and control.
Key preventive measures include:
Personal Protection
Avoid contact with sick individuals.
Avoid contact with blood and body fluids.
Wash hands frequently with soap and water or alcohol-based hand rub.
Practice good personal hygiene.
Food Safety
Avoid handling sick or dead wild animals.
Ensure all animal products are thoroughly cooked before consumption.
Community-Level Measures
Prompt reporting of suspected cases.
Active surveillance and contact tracing.
Community awareness and health education.
Safe and dignified burial practices.
Isolation and treatment of suspected and confirmed cases.
Health Facility Measures
Strict adherence to Infection Prevention and Control (IPC) protocols.
Proper use of Personal Protective Equipment (PPE).
Safe injection practices.
Environmental cleaning and disinfection.
Appropriate waste management procedures.
INFECTION PREVENTION AND CONTROL (IPC) FOR HEALTHCARE WORKERS
Healthcare workers should consistently apply standard precautions, including:
Hand hygiene
Respiratory hygiene
Appropriate use of PPE
Safe injection practices
Safe specimen handling
Proper waste disposal
Environmental decontamination
Additional precautions are required when caring for suspected or confirmed Ebola patients to prevent exposure to infectious materials.
CARE AND SUPPORT FOR SURVIVORS
Survivors of Ebola Disease may experience long-term physical, psychological, and social challenges, including:
Fatigue
Joint and muscle pain
Eye complications
Psychological distress
Social stigma
Comprehensive survivor support should include:
Medical follow-up care
Mental health services
Community reintegration support
Counselling services
Reproductive health services
Male survivors should receive counselling regarding safer sexual practices, as Ebola virus may persist in semen for extended periods after recovery.
PUBLIC HEALTH RESPONSE
Successful Ebola outbreak response requires coordinated action among government agencies, healthcare workers, partners, communities, and international organizations.
Critical response activities include:
Surveillance and early warning systems
Rapid case detection and investigation
Laboratory confirmation
Contact tracing
Case management
Risk communication and community engagement
Safe and dignified burials
Logistics and supply chain management
Healthcare worker training
Vaccination where indicated
CONCLUSION
Ebola Disease remains a significant public health threat due to its high mortality rate and potential for rapid spread. However, timely detection, prompt reporting, effective infection prevention measures, community engagement, and quality clinical care can significantly reduce transmission and save lives.
Early reporting, early isolation, and early treatment save lives.
For Any Suspected Ebola Case:
Immediately notify the Disease Surveillance and Notification Officer (DSNO), State Epidemiologist, or the nearest health authority for prompt investigation and response, or call the following numbers:
State Epidemiologist
0803 872 2244
State DSNO
0803 792 1118
AKISEMSAS: 08000022322
08000022422