Al-Xariiri Pharmacy

31/05/2026

A major new scientific review found that ni****ne based e-ci******es are carcinogenic to humans, driving up risks for oral and lung cancers.

A comprehensive global review published in the journal Carcinogenesis has delivered a stark warning about the long-term safety of electronic ci******es.

Led by cancer researchers at UNSW Sydney, the study assessed clinical data, animal experiments, and laboratory research to determine the direct health impacts of va**ng independent of traditional to***co.

The findings indicate that e-cigarette aerosols contain potentially carcinogenic compounds—such as formaldehyde, acetaldehyde, and heavy metals like nickel and lead—which cause DNA damage, oxidative stress, and chronic inflammation. These physiological changes occur directly in oral and respiratory tissues, leading researchers to conclude that ni****ne-based vapes are likely to cause both lung and oral cancers.

Public health experts, including former Baltimore Health Commissioner Dr. Leana Wen, urge the public to recognize that 'safer than smoking' does not mean safe. Although e-ci******es avoid the combustion-related toxins of traditional to***co, ni****ne itself remains highly addictive and can promote tumor growth and blood vessel formation. With e-ci******es yet to be approved by the FDA as smoking cessation tools, experts warn that dual use is highly common and that many people switch systems without breaking their ni****ne dependency. Because va**ng has only been popular for roughly two decades, definitive long-term epidemiological data on human cancer rates will take decades to fully mature, but the immediate biological cellular damage is already clear.

source: Hetter, K. (2026). Va**ng is often touted as less toxic than smoking. But new research raises concerns about cancer risk.CNN.

29/04/2026

*Sugar and processed foods are highly inflammatory. They can lead to insulin resistance which can enhance probability of developing metabolic syndrome. ⁣As it’s a stimulator of inflammation it can therefore cause an increase in severity of thyroid diseases. ⁣ ⁣

*Stress causes a chronic release of cortisol which causes immune system problems, and increase in inflammation.
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*Gluten inflames the gut and elicits an immune response.
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*Unfermented soy in form of soy milk, tofu, soybeans, edamame, soy cheese etc, are rich in anti nutrients. ⁣Anti nutrients are thyroid disruptors and predispose to cancer, among other risks like fatty liver diseases and infertility. ⁣
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*The Gut controls over 80 percent of the immune system, if anything goes wrong, an imbalance occurs. Gut Problems are highly connected to immune system and inflammation. Gut problems occurs through any of the triggers listed. If the gut microbiome is impaired, the whole body can suffer from it. ⁣
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22/04/2026

30/03/2026

You may have heard that if you have Hashimoto’s, it’s important to eat enough protein. Eating plenty of protein can help keep your blood sugar stable, help support energy levels and mood, and support a healthy weight.

Of course, we should be getting most of our protein from whole food sources, but those with Hashimoto’s may be sensitive to certain types of protein like dairy, whey, eggs, beans, or legumes.

This can make getting enough protein challenging. That’s where protein powders come in! They can truly be such a great supplemental way to get an extra serving of protein in your day, in a really convenient way.

But not all protein powders are created equal – many contain fillers, artificial sweeteners, and other ingredients that those with Hashimoto’s may not tolerate.

20/03/2026

19/03/2026

Did you know that these conditions are different and may require different treatments?⁠
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The thyroid gland is an incredibly important organ and influences things like your heart rate, digestion, mood, menstrual cycle, and energy levels—essentially various factors of your metabolism.⁠
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Thyroid problems are very common. There are 2 specific conditions that are quite commonly under diagnosed, you may have one or the other or even both together.

However, they do require different treatments.⁠
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👉Hypothyroidism simply refers to a state of low thyroid function in the body. This state is almost always the result of decreased thyroid hormone production. When this happens, you can experience symptoms like fatigue, cold intolerance, constipation, muscle weakness, hair loss, brain fog and poor concentration, a “slow metabolism” with weight gain and other hormonal issues.⁠
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👉Hashimotos is an auto-immune disease and may be associated with episodes of hyperthyroidism, normal thyroid function, and hypothyroidism. Hashimotos is when the immune system produces antibodies that attack the tissues of the thyroid gland. These antibodies cause inflammation and destruction to the thyroid gland creating a much more serious and chronic thyroid condition, than hypothyroidism.

19/03/2026

Researchers are increasingly investigating sildenafil (Vi**ra) as a possible treatment for Alzheimer’s disease. Large observational studies have found that people taking sildenafil were significantly less likely to develop Alzheimer’s, with one analysis suggesting up to a ~70% lower risk compared with non-users.
Scientists think the drug may help by improving blood flow in the brain and affecting cellular pathways linked to memory and neuron health, but researchers stress that the results so far show correlation, not proof of causation, and clinical trials are still needed.

19/03/2026

Izabella, a Thriod Pharmacist said, Early on in my Hashimoto’s journey, I experienced a lot of digestive symptoms and discomfort, most of which I didn’t initially link to hypothyroidism or my autoimmune condition.

What I didn’t understand at the time was how closely gut health is tied to thyroid and immune system health!

The gut microbiome describes the trillions of bacteria and the substances they produce, found primarily in the large intestine.

The gut microbiome supports the gut’s protective mucus barrier lining. This barrier allows vital nutrients from our digested food to be absorbed into the bloodstream, while simultaneously blocking the entry of bacteria and toxins.

When things go awry, this mucus barrier can break down, increasing intestinal permeability and resulting in “leaky gut.” Partially digested food, bacteria, and other toxins are then able to pass through the damaged barrier and are freely absorbed into the bloodstream, activating the immune system.

Researchers have connected intestinal permeability to every case of autoimmune disease, including Hashimoto’s, and it also sometimes plays a role in IBS. Studies have found that people with IBS are likely to have increased intestinal permeability, with certain types of IBS being more prone to it.

Source:Thriod Pharmacist .

14/03/2026

The 200-million-strong population of type-2 diabetics in China carries a treatment burden that is as much behavioral as physiological: multiple daily blood glucose checks, insulin injections, or oral medications requiring strict adherence. 💉 Bioengineers at Peking University have taken inspiration from the 3,000-year-old practice of acupuncture — the application of fine needles at specific meridian points — to design a skin-worn nanopatch with arrays of 500-micrometer solid microneedles that passively regulate glucose by stimulating insulin-releasing nerve pathways while simultaneously delivering a micro-dose of exendin-4 (a GLP-1 analogue) through the skin at a rate proportional to interstitial glucose concentration.

Published in Nature Biomedical Engineering (2025), the glucose-responsive nanopatch uses phenylboronic acid-modified microneedles that physically swell in proportion to ambient glucose levels, increasing drug permeation rate as glucose rises and self-limiting delivery as levels normalize — creating a closed-loop pharmacological system requiring no electronics. In a 90-patient crossover trial against oral metformin, the nanopatch produced superior time-in-range metrics (89% vs 71%), lower HbA1c reduction (-1.8% vs -1.1%), and dramatically improved patient-reported quality of life. 🔬 Participants replaced twelve daily interventions with a single patch change every 72 hours.

The acupuncture-point rationale is more than marketing. The specific meridian points used — ST36, SP6, and KI3 — are innervated by peripheral nerve branches that project to the hypothalamus and vagal nuclei regulating glucose homeostasis. Neuro-stimulation from the microneedles modulates insulinotropic signals independent of the pharmacological payload, producing a synergistic effect the team quantified as responsible for approximately 30% of the observed glucose reduction.

Manufacturing scale-up has begun with a Chinese pharmaceutical partner. 🌐 The combination of traditional medical knowledge and nanotechnology represents a genuinely novel translational pathway — and raises the question of how many other ancient therapeutic intuitions might be encoding pharmacological truths we've yet to rigorously test.

Source: Peking University, Nature Biomedical Engineering, 2025

14/03/2026

This microscopic 'genetic pirate' is rewriting the rules of evolution.

It steals functional DNA from the plants and bacteria it eats.

Microscopic bdelloid rotifers are challenging our traditional understanding of genetics by acting as biological scavengers. These tiny aquatic creatures possess a genome where nearly 10% of their active genes originate from foreign sources, including bacteria, fungi, and plants. By utilizing specialized 'chainsaw' mouthparts to grind up their food, they release genetic material that eventually integrates into their own DNA. This extraordinary process, known as horizontal gene transfer, allows them to acquire complex functional traits—such as the ability to produce antibiotics—directly from the organisms they consume.

The secret to this genetic theft lies in the rotifer’s remarkable resilience to extreme dehydration. When these organisms undergo desiccation, their chromosomes fracture into pieces. Upon rehydration, their highly efficient DNA repair mechanisms kick into gear, stitching their genetic code back together while inadvertently weaving in fragments of foreign DNA present in their cells. This unique evolutionary adaptation not only facilitates rapid genetic diversification but also equips the rotifers with the metabolic tools necessary to thrive in volatile environments that would be fatal to most other animals.

source: National Institutes of Health. (2021). Horizontal Gene Transfer and DNA Repair in Bdelloid Rotifers. National Center for Biotechnology Information.