05/04/2026
ften discuss equine feed-through joint supplements with clients.
For a little perspective, here’s research on a widely used and very popular oral joint supplement showing no meaningful improvements in gait, inflammation, or cartilage biomarkers in horses compared to a placebo.
It’s also worth noting that, more broadly, research in horses has been inconsistent at best, with common ingredients like glucosamine and chondroitin showing limited bioavailability and little reliable evidence of efficacy at typical feeding rates.
Here’s the link:
https://www.facebook.com/share/p/14Z9iSX5mPM/
𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐔𝐩𝐝𝐚𝐭𝐞: 𝐀𝐫𝐞 𝐨𝐫𝐚𝐥 𝐣𝐨𝐢𝐧𝐭 𝐬𝐮𝐩𝐩𝐥𝐞𝐦𝐞𝐧𝐭𝐬 𝐚𝐜𝐭𝐮𝐚𝐥𝐥𝐲 𝐞𝐟𝐟𝐞𝐜𝐭𝐢𝐯𝐞 𝐟𝐨𝐫 𝐡𝐨𝐫𝐬𝐞𝐬? 🦴🐴
Equine osteoarthritis is one of the most common chronic conditions affecting horses (Baccarin et al., 2022). So naturally, we’re always looking for ways to manage it, especially in our equine athletes and aging horses who experience higher joint strain.
One of the most common questions I get during consults is about oral joint supplements. They’re appealing for good reason: non-invasive, easy to feed, and widely available. But they’re also expensive and the science behind them has been mixed.
In fact, one study found 48% of horse owners felt there wasn’t enough research to support joint supplement efficacy, yet 90% were still willing to use them for prevention or treatment (Swirsley et al., 2017). That gap likely comes from the mindset “They might not help, but they won’t hurt.”
And that’s understandable when you’re dealing with a condition as common and impactful as osteoarthritis, doing something feels better than doing nothing.
But here’s the good news 👇
Researchers at Michigan State University have been working to give us clearer answers, and a newly published study is helping move the conversation forward (Harbowy et al., 2026). Article linked in comments!
➡️ Let’s break down what this new research actually tells us…
🔬 𝐌𝐚𝐭𝐞𝐫𝐢𝐚𝐥𝐬 𝐚𝐧𝐝 𝐌𝐞𝐭𝐡𝐨𝐝𝐬 (𝐚𝐧𝐝 𝐰𝐡𝐲 𝐢𝐭 𝐦𝐚𝐭𝐭𝐞𝐫𝐬!)
Researchers at Michigan State University evaluated 40 horses with chronic lameness (AAEP 2–4) associated with osteoarthritis.
Horses were carefully balanced by age, body condition, weight, and anticipated workload, then assigned to:
• A joint supplement group (Cosequin ASU)
• A control group (placebo; all-purpose flour)
To strengthen the study, each of these groups were further divided into two sub-groups and assigned different colors and scented additives to keep the treatments blinded and also create the perception there were four treatments to rule out any bias.
This is a strong experimental design addressing common issues seen in supplement research such as small sample sizes, lack of controls, and bias. This is important because the quality of the design determines how well we can interpret and ultimately trust the results.
𝐑𝐞𝐬𝐮𝐥𝐭𝐬
Horses were evaluated every other week over 6 weeks and numerous variables were considered at each timepoint:
Lameness Grade: Treatment did not impact lameness grade (P>0.05) but all horses showed improvements between day 0 and 28 (P=0.045).
Forelimb Vector Sum: Horses on the oral joint supplement had greater forelimb asymmetry than those in the control group (P=0.042).
Pelvic Height: Treatment did not impact minimum or maximum pelvic height.
Stride Length: The stride length at the walk and trot did not differ between treatments.
𝐃𝐢𝐬𝐜𝐮𝐬𝐬𝐢𝐨𝐧
𝑾𝒉𝒂𝒕 𝒅𝒐𝒆𝒔 𝒕𝒉𝒊𝒔 𝒎𝒆𝒂𝒏?
Overall, the oral joint supplement did not contribute to any positive changes in horses with osteoarthritis. These findings are not surprising and do align with previous research. While in vitro (cell culture) studies showed promise, studies completed in vivo (in the horse) had unclear clinical implications.
𝑾𝒉𝒚 𝒅𝒐𝒆𝒔 𝒕𝒉𝒊𝒔 𝒎𝒂𝒕𝒕𝒆𝒓?
Joint supplements are a huge supplement category and historically have contributed to 34% of supplement sales (Oke et al., 2010). This is likely because equine osteoarthritis is the leading cause of lameness in horses (McIlwraith et al. 2012). This degenerative joint disease has been shown to affect an estimated 50% of horses over the age of 15 and up to 90% of horses 30 years and older (van Weeren et al., 2016).
𝐌𝐲 𝐓𝐚𝐤𝐞𝐚𝐰𝐚𝐲𝐬
Overall, the evidence suggests that joint supplements may not be a worthwhile investment. Instead, focus on:
🥗 Balancing the diet to ensure nutrient requirements are met and the horse maintains a healthy weight.
🏡 Ensuring housing emphasizes adequate turnout time instead of prolonged stall confinement
🐎 Building exercise programs that include warm-up and cool down-periods and focus on consistent low impact movement, strengthening exercises, cross training, and proper conditioning
𝐁𝐨𝐭𝐭𝐨𝐦 𝐋𝐢𝐧𝐞: While feeding a joint supplement may be easy, a well-rounded and holistic management approach is more likely to support your horse’s joint health in the long run.
* I’ll add that, yes, this study evaluated a single supplement. However, many joint supplements on the market contain similar ingredients, often at even lower inclusion rates. While I’ll continue digging into the literature, there currently isn’t strong, consistent evidence identifying a specific ingredient or combination that reliably improves osteoarthritis outcomes in horses. And realistically, if a clearly effective option existed, it would be widely recognized and supported by the research at this point.
But now I am curious - Do you currently feed a joint supplement and will this impact your decision to use one in the future?
Cheers,
Dr. DeBoer
Baccarin, RYA, Seidel SRT, Michelacci YM, Tokawa PKA, Oliveira TM. Osteoarthritis: A common disease that should be avoided in the athletic horse’s life. Anim. Front. 2022;12:25–36.
Swirsley N, Spooner HS, Hoffman RM. Supplement use and perceptions: a study of US horse owners. Journal of equine veterinary science. 2017 Dec 1;59:34-39.
Harbowy RM, Robison CI, Tillman I, Manfredi JM, Nielsen BD. Efficacy of an oral chondroprotective joint supplement on stride length and gait symmetry in aged geldings with chronic lameness. Animals. 2026;6(8):1230.
Oke S, McIlwraith CW. Review of the economic impact of osteoarthritis and oral joint supplement use in horses. AAEP Proc. 2010;56:12-16.
McIlwraith CW, Frisbie DD, Kawcak CE. The horse as a model of naturally occurring osteoarthritis. Bone Joint Res. 2012;1(11):297–309.
van Weeren PR, Back W. Musculoskeletal disease in aged horses and its management. Vet. Clin. N. Am. Equine Pract. 2016;32:229-247.