APS Foundation of America, Inc.

APS Foundation of America, Inc. Founded in 2005, APS Foundation of America, Inc. We are a volunteer-run, community-based 501(c)3 non-profit Public Charity organization. Thank you.

The APSFA is bringing awareness to Antiphospholipid Syndrome (APS), a rare autoimmune clotting disorder that causes young strokes, multiple miscarriages, stillbirths, thrombosis & heart attacks, and much more. (APSFA) is the only United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Syndrome (APS), the primary cause of multiple miscarriages, thrombosis,

young strokes, and heart attacks. We are dedicated to fostering and facilitating joint efforts in education, support, public awareness, research, and patient services. The APSFAโ€™s Medical Advisory Team includes nationally & internationally recognized experts on Antiphospholipid Syndrome.

*Disclaimers*
The Founders, Administrator (s), Assistant(s), Helper(s), Greeter(s) & Staff of this forum are not medical doctors. This forum's Founders, Administrator(s), Assistant(s), Helpers, Greeters & Staff are not medical doctors. APS Foundation of America is not intended to replace standard doctor-patient visits, physical examination, and medical testing. Information given to members is only an opinion. All information should be confirmed with your personal doctor. Always seek a trained physician's advice before seeking any new treatment regarding your medical diagnosis or condition. Any information received from the APS Foundation of America is not intended to diagnose, treat, or cure. This site is for informational purposes only. Additionally, while APS Foundation of America, Inc. frequently updates its content, medical information changes rapidly; therefore, some information may be outdated when you read it.

**If you think you may have a medical emergency, call your doctor or 911 immediately.**

If you use this page, we want you to know that you are solely responsible for your communications, the consequences of posting those communications, and your reliance on any communications found in those areas. APS Foundation of America, Inc., and its licensors are not responsible for the consequences of any communications in the forum, chat room or page. If you give your personal information to a host or other member and later threaten to hurt yourself or others, we reserve the right to contact appropriate authorities; however, no guarantee is made that someone will contact emergency personnel for you. We are not equipped to handle these types of crisis situations. You should contact your local law enforcement agency right away. Members agree to accept personal liability for any medical advice they provide to another member. Furthermore, anyone who accepts and applies medical advice from another member agrees that they are doing so at their own risk and will hold APSFA, its affiliates, employees, and volunteers harmless.

**All posts are moderated 24/7 and are subject to deletion for any reason.**

Medical journal articles do not constitute medical advice. Please share these with your medical care team. Page rules can be found here:http://apsfa.org/new/wp-content/uploads/2022/01/APSFA-Rules.pdf

We are a volunteer-run, community-based 501(c)3 non-profit Public Charity organization. The person who does the majority of the work has multiple autoimmune disorders is on biologics, chemotherapy, and multiple drugs to try to control them and also needs her rest. The rest of the board is just as sick. To be upset we are not available 24/7, 365 when our whole board has this disease and other autoimmunes as well is quite disappointing. We are doing our best as volunteers.

09/05/2026

Credit to Ky Paige ๐ŸŒž The chronic illness trap: Talk about your illness and people think youโ€™re faking, lying, exaggerating, or being too negative.

DONโ€™T talk about your illness and people think youโ€™re magically healed - and they expect far more of you than your ability or capacity level allows.

Let me know if you can relate!

09/05/2026

Credit to

Truth, if they only knew.

09/05/2026

Credit to Alec Bradbury

โ€ผ๏ธ WANT to apologize? Totally fine. But no one should MAKE you feel like you need to apologize for your medical complexities.

Itโ€™s normal to feel like a burden and itโ€™s normal to feel the need to apologize to those who make sacrifices for you. Sometimes apologies can be therapeutic for both parties.

But people need to skip the guilt-tripping, the gaslighting, the microaggressions, and the outright verbal abuse (especially from us providers!) that make you feel the need to apologize. Thatโ€™s toxic and thereโ€™s no place for it.

You deserve better ๐Ÿซถ

๐—–๐—ผ๐˜‚๐—น๐—ฑ ๐˜๐—ต๐—ฒ ๐—น๐—ฒ๐˜ƒ๐—ฒ๐—น ๐—ผ๐—ณ ๐—ฝ๐—ฒ๐—ฟ๐˜€๐—ถ๐˜€๐˜๐—ฒ๐—ป๐˜ ๐—ฎ๐—ป๐˜๐—ถ๐—ฝ๐—ต๐—ผ๐˜€๐—ฝ๐—ต๐—ผ๐—น๐—ถ๐—ฝ๐—ถ๐—ฑ ๐—ฎ๐—ป๐˜๐—ถ๐—ฏ๐—ผ๐—ฑ๐—ถ๐—ฒ๐˜€ ๐—ต๐—ฒ๐—น๐—ฝ ๐˜๐—ฒ๐—น๐—น ๐˜‚๐˜€ ๐—บ๐—ผ๐—ฟ๐—ฒ ๐—ฎ๐—ฏ๐—ผ๐˜‚๐˜ ๐˜€๐˜๐—ฟ๐—ผ๐—ธ๐—ฒ ๐—ฟ๐—ฒ๐—ฐ๐˜‚๐—ฟ๐—ฟ๐—ฒ๐—ป๐—ฐ๐—ฒ?A new study followed...
09/05/2026

๐—–๐—ผ๐˜‚๐—น๐—ฑ ๐˜๐—ต๐—ฒ ๐—น๐—ฒ๐˜ƒ๐—ฒ๐—น ๐—ผ๐—ณ ๐—ฝ๐—ฒ๐—ฟ๐˜€๐—ถ๐˜€๐˜๐—ฒ๐—ป๐˜ ๐—ฎ๐—ป๐˜๐—ถ๐—ฝ๐—ต๐—ผ๐˜€๐—ฝ๐—ต๐—ผ๐—น๐—ถ๐—ฝ๐—ถ๐—ฑ ๐—ฎ๐—ป๐˜๐—ถ๐—ฏ๐—ผ๐—ฑ๐—ถ๐—ฒ๐˜€ ๐—ต๐—ฒ๐—น๐—ฝ ๐˜๐—ฒ๐—น๐—น ๐˜‚๐˜€ ๐—บ๐—ผ๐—ฟ๐—ฒ ๐—ฎ๐—ฏ๐—ผ๐˜‚๐˜ ๐˜€๐˜๐—ฟ๐—ผ๐—ธ๐—ฒ ๐—ฟ๐—ฒ๐—ฐ๐˜‚๐—ฟ๐—ฟ๐—ฒ๐—ป๐—ฐ๐—ฒ?

A new study followed 47 people who had experienced a cryptogenic stroke or TIA and continued to test positive for antiphospholipid antibodies (aPLs) for at least 12 weeks.

Researchers found that recurrent ischaemic stroke was less common in people with weakly positive aPLs than in those with strongly positive aPLs.Treatment patterns also differed: antiplatelet medicines were recommended more often in the weakly positive group, while warfarin was more commonly recommended for those with strongly positive aPLs.

Itโ€™s an interesting finding, but the study was small, retrospective and carried out within one health system. The researchers say larger prospective studies and randomized trials are needed to better understand the best treatment approach.

Read the study: https://pubmed.ncbi.nlm.nih.gov/42668533/

09/05/2026

Syndrome ( ): How it happens in your blood, the warning signs, and what to do about it.

Antiphospholipid Syndrome is an autoimmune disorder that affects your blood's ability to clot properly, increasing the risk of blood clots in veins and arteries. It happens when your immune system mistakenly produces antibodies against phospholipids, which are essential for normal blood clotting. This can lead to complications like deep vein , pulmonary embolism, or even and .

# # # Warning Signs to Watch For: - **Unexplained Clots:** Sudden swelling or pain in your limbs may signal a clot. - **Recurrent Miscarriages:** Women may experience repeated pregnancy losses. - **Fatigue and Headaches:** Persistent fatigue, migraines, or unexplained headaches can be indicators.

# # # What You Can Do: - **Consult a Doctor:** If you notice any symptoms or have a family history, seek medical advice for a proper diagnosis. - **Regular Check-Ups:** Stay on top of your health with regular screenings for clotting issues. - **Manage Risk Factors:** Maintain a healthy lifestyle, stay hydrated, and avoid smoking to reduce your risk.

Stay informed and proactive to keep your blood health in check!

Study Alert:In brief, weโ€™re conducting this study to investigate the pathogenic autoantibodies that drive   Syndrome ( )...
09/05/2026

Study Alert:

In brief, weโ€™re conducting this study to investigate the pathogenic autoantibodies that drive Syndrome ( ). The study aims to understand how these autoantibodies bind to an investigational that specifically only these pathogenic autoantibodies. Participants can enroll and participate from home and will be for their time.

Learn more: https://studies.sanguinebio.com/condition/aps/
Call: (617) 765-1394

09/04/2026

๐Ÿง  ๐—–๐—ฎ๐—ป ๐˜€๐˜๐—ฟ๐—ฒ๐˜€๐˜€ ๐—ฎ๐—ณ๐—ณ๐—ฒ๐—ฐ๐˜ ๐—ฎ๐˜‚๐˜๐—ผ๐—ถ๐—บ๐—บ๐˜‚๐—ป๐—ฒ ๐—ฑ๐—ถ๐˜€๐—ฒ๐—ฎ๐˜€๐—ฒ?

Research suggests that severe or prolonged stress can affect the immune system and has been associated with an increased risk of some autoimmune diseases.

A large study published in JAMA, involving more than 100,000 people with stress-related disorders, found an association between stress-related disorders and the subsequent development of autoimmune disease.

But thereโ€™s an important distinction: an association does not mean that stress directly causes autoimmune disease.

When it comes to antiphospholipid syndrome (APS), we still donโ€™t know exactly why some people develop the condition. Stress has been suggested as one of several possible triggers, but much more research is needed.

๐Ÿ‘‰ Find out more about the possible causes and triggers of APS: https://aps-support.org.uk/about-aps/what-causes-it

๐Ÿ”ฌ Read the JAMA study: https://jamanetwork.com/journals/jama/fullarticle/2685155

09/04/2026

๐Ÿงฌ ๐—–๐—ผ๐˜‚๐—น๐—ฑ ๐—ฑ๐—ถ๐—ณ๐—ณ๐—ฒ๐—ฟ๐—ฒ๐—ป๐˜ ๐—ฝ๐—ฒ๐—ผ๐—ฝ๐—น๐—ฒ ๐˜„๐—ถ๐˜๐—ต ๐—”๐—ฃ๐—ฆ ๐—ต๐—ฎ๐˜ƒ๐—ฒ ๐—ฑ๐—ถ๐—ณ๐—ณ๐—ฒ๐—ฟ๐—ฒ๐—ป๐˜ ๐˜‚๐—ป๐—ฑ๐—ฒ๐—ฟ๐—น๐˜†๐—ถ๐—ป๐—ด ๐—บ๐—ผ๐—น๐—ฒ๐—ฐ๐˜‚๐—น๐—ฎ๐—ฟ ๐—ฝ๐—ฎ๐˜๐˜๐—ฒ๐—ฟ๐—ป๐˜€?

New research has explored the immune pathways involved in antiphospholipid syndrome (APS), identifying two areas of particular interest: type I interferon signalling and changes in the behaviour of certain B cells.

The researchers suggest these molecular differences could one day help scientists better understand why APS varies so much from person to person โ€” and potentially support more targeted approaches to treatment in the future.

Importantly, this was a computational research study, not a clinical trial, and the potential treatment targets identified still need laboratory and clinical testing.

Itโ€™s an interesting step towards understanding the biology behind APS in greater detail.

๐Ÿ”— Read the study: https://pubmed.ncbi.nlm.nih.gov/42647509/

Prevalence and outcomes of antiphospholipid syndrome after unprovoked venous thromboembolism: a multicenter real-world d...
09/04/2026

Prevalence and outcomes of antiphospholipid syndrome after unprovoked venous thromboembolism: a multicenter real-world data analysis

Guidance for antiphospholipid antibody (aPL) testing after unprovoked venous thromboembolism (VTE) is inconsistent. Real-world data on the prevalence and outcomes of antiphospholipid syndrome (APS) in those presenting with unprovoked VTE are limited.

The prevalence of APS following unprovoked VTE is notable, and selective testing identified fewer APS cases in practice. Identifying aPLs in patients with unprovoked VTE may inform discussions regarding anticoagulation duration and choice, although optimal testing strategies require further prospective evaluation.

Read More Here: https://www.jthjournal.org/article/S1538-7836(26)00288-6/fulltext

September is recognized as Pain Awareness Month, a crucial time to shine a light on the challenges faced by millions dea...
09/03/2026

September is recognized as Pain Awareness Month, a crucial time to shine a light on the challenges faced by millions dealing with chronic pain. This month serves as a reminder to educate ourselves and others about the complexities of pain, its impact on daily life, and the importance of empathy towards those who suffer. Itโ€™s also about advocating for better treatment options, research, and support systems.

Letโ€™s take this opportunity to share stories, foster understanding, and encourage open conversations around pain management. Whether youโ€™re affected personally or know someone who is, your voice matters. From discussing coping strategies to highlighting the emotional and psychological aspects of pain, every discussion helps create a more supportive community. Together, we can raise awareness, promote healing, and work towards innovative solutions to enhance the quality of life for those living with pain.

Share your experiences and letโ€™s empower one another this September!

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La Crosse, WI

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