09/25/2026
This is the most recent news on Frontiers in Genetics ( courtsey Dr David perlmutter)
Dr Adiv Johnson and Dr David Sinclair have systematically reviewed 41 human interventional studies which measured the effects of various treatments on next generation epigenetic aging clocks knows as DNA methylation patterns which can estimate the persons biological age .
This is a next generation clock esp trained to predict outcomes including mortality risks , disease risks , inflammation and overall health .
The results are as follows /
(1) Regular endurance exercise - consistently favorable
(2) plant rich diet - favorable
(3) caloric restriction - favorable
(4) omega -3 fatty acid - favorable
(5) multivitamin - modest benefit
(6) semaglutide ( GLP-1 ) - strongest positive findings .
Statins , metformin , ketamine , Rapamycin , Nicotinamide riboside , senolytics etc had minimal or no effect at all .
These are the same recommendations for improving metabolic health .
so let us work on these
