26/06/2026
Bipolar depression remains one of the most challenging conditions to treat, particularly when traditional antidepressants are ineffective or carry risks of mood destabilization. Emerging research has highlighted ketamine as a promising option for treatment-resistant bipolar depression, with evidence suggesting rapid improvements in depressive symptoms and suicidality in some patients.
In Dr. Gail Serruya’s blog, we explore the current research on ketamine in bipolar depression, its mechanism of action, important safety considerations, including the need to avoid use during manic or mixed states, and how it may fit into a carefully monitored treatment plan alongside mood stabilizers and clinical oversight.
At Voyage Healing, we focus on advancing bipolar depression care through integrative, evidence-informed approaches that prioritize safety, precision, and individualized treatment planning.
Read the full article on our website to learn more