04/13/2026
There’s a lot of misinformation circulating about progesterone—and it’s time to ground ourselves in evidence, not fear.
Progesterone plays an important role in hormone therapy, especially for people with a uterus using estrogen. Decades of research show that adding progesterone helps protect the endometrium from hyperplasia and cancer. That’s not opinion—that’s well-established, evidence-based care supported by large clinical studies and long-term data.
At the same time, not all progesterone is the same, and not all uses are backed by science. Some claims being circulated today rely on small, poorly designed studies—or are taken out of context to push narratives that don’t reflect real clinical evidence.
We’re seeing how quickly nuanced medical topics get distorted into harmful narratives—especially when it comes to reproductive and hormonal health. Sound familiar?
Whether it’s menopause care or abortion care, the pattern is the same: misinformation spreads fast, and people deserve better.
Let’s be clear:
Evidence-based care matters
Study quality matters
Nuance matters
People deserve accurate information and autonomy
If you want a clear, evidence-based breakdown, I highly recommend reading this article from Vajenda ("Progesterone in MHT for Protection Against Endometrial Cancer")—it does an excellent job unpacking the science and the myths.
We trust people with the truth—not politics, not stigma, not pseudoscience.