06/13/2026
Screening for leaky gut and dysbiosis is done in office at the Natural Medicine Institute. Follow up additional lab testing can pin point the underlying cause.
I have this conversation with patients regularly. They come in frustrated, having been told their colonoscopy was normal, their endoscopy was normal, their standard blood work was fine. And yet they are dealing with bloating, irregular bowel habits, food sensitivities, fatigue, and brain fog that nobody can explain.
The disconnect is a testing gap, not a diagnostic mystery.
A colonoscopy is a structural examination. It is looking for cancer, polyps, and visible inflammatory bowel disease. It is an important test for those purposes. What it cannot do is evaluate the functional and microbial environment of the gut, which is where most of the chronic digestive dysfunction I see in practice actually lives.
The GI-MAP stool analysis is the test I use when I want to understand what is actually happening in a patient's gut. It looks at bacterial pathogens, opportunistic bacteria, parasites, fungi including Candida, H. pylori, markers of intestinal inflammation like calprotectin and zonulin, and digestive enzyme output. These are the factors that drive symptoms like bloating, constipation, loose stools, food reactivity, and the systemic issues that flow downstream from a compromised gut including mood disruption, skin conditions, and hormonal imbalance.
The standard gastroenterology workup is designed to rule out serious disease. The functional medicine workup is designed to understand how the gut is actually functioning. Those are two different questions, and most patients only ever get an answer to the first one.
Want to know what is actually going on in your gut? Get my Free Balance Toolkit — comment BALANCE.
Research: Camilleri M. "Leaky gut: mechanisms, measurement and clinical implications in humans." Gut. 2019;68(8):1516-1526. https://doi.org/10.1136/gutjnl-2019-318427