05/21/2026
GLPs are not going away anytime soon, matter of fact, the market is about to expand so much that I think it is so important for all people to understand how the conversations are shifting. There are many people on social media who don't understand the differences between degrees of muscle losses. What I mean by this is, everyone thinks that just because you are on a weight loss medication like a GLP-1 the weight loss will be "bad", or "complete muscle or bone loss".
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I can’t stress this enough to everyone. Understand that ANY weight loss, induces some degree of muscle loss-doesn't matter if that weight loss was through lifestyle (w/o meds), surgical, or pharma, this is not new to the medical world. Unfortunately, we are just now catching up, and it has just become more popular to talk about because of GLPs.
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The real question we should be looking at is how are we assessing the "muscle composition" when losing weight? AGAIN-Doesn't matter how you are losing weight. Please reread that, because again if you are still in a calorie deficit, NOT on a GLP1, how are you 100% positive you are certain that you know the overall composition of your body?
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Some of the standout questions to ask yourself when losing weight:
• How much weight have I lost over time-is it more than 5-10% of your body weight in a 6-12 month period?
• If you have had extreme weight loss how are you measuring it outside of a scale?-Have you had a DEXA scan, BIA measurements, recent MRIs, etc.
• Do you and your doctors understand the differences between fat-free mass and muscle?
• Do you understand that Obesity impacts muscle quality through fat accumulation, inflammation and impaired metabolic function?
• Do you understand that muscle function matters more than mass alone? (e.g handgrip strength, jump tests, loaded stair climb, etc vs. just bench pressing or doing bar loaded squats)
• Do you understand that mobility is also important when losing weight and maintaining muscle?
• Do you understand that preserving muscle in obese people for weight loss may differentiate by how well the muscle is already preserved and its physical function?
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I understand there are some very "sciencey" terms here. But to summarize what I am saying, it is best for anyone who is losing weight significantly over time, no matter how they are doing it, to dive deeper into evaluating the compositional and functional changes of their weight. Talk to your doctors who understand DEXA scans, work with obesity clinics and know how to compare previous readings. Not everyone is created equal in this journey! 🫶🏽