28/05/2026
New episode is live! Surgery vs. Biologics for Nasal Polyps: What Doctors Know Now w/ Dr. Tassos Hantzakos & Dr. Dipa Sheth Check it out- https://www.drdeepa-tlc.org/blog/hantzakos-sheth
When it comes to treating chronic sinus disease with nasal polypsâŚwhatâs the best approach, surgery or biologics?
Well, the answer is itâs usually not either-or anymore.
When patients are trying to manage these challenging conditions, some people opt for one or the other. But more physicians are finding that surgery and biologics arenât different paths. They are actually treatment protocols that complement each other.
Surgery may remove the growths, but it doesnât necessarily stop the process of creating them in the first place. Biologics may suppress the inflammatory pathways driving recurrence, but they donât physically restore blocked sinus anatomy or remove bulky disease.
Weâre entering a new phase of care where the question is no longer âsurgery or biologics?â but how both can work together as part of a personalized strategy.
Instead of treating every patient the same way, physicians are now looking deeper at the inflammatory pathways driving disease, recurrence risk, quality of life, and even how different biologics target different parts of the immune cascade.
The shift is moving chronic sinus care away from a one-size-fits-all model and toward precision medicine thatâs designed around the individual patient.
In this episode, Iâm joined by Dr. Tassos Hantzakos, staff physician in otolaryngology and residency program director at Cleveland Clinic Abu Dhabi, and Dr. Deepa Sheth, allergy and immunology specialist.
Together, we break down how the treatment landscape for chronic rhinosinusitis with nasal polyps is evolving, why collaboration between ENT and allergy specialists is becoming essential, and how biologics are reshaping the future of inflammatory airway disease management.
