19/10/2026
The liver seems to get all the credit for what is definitely a group assignment.
Yes, your liver is incredibly important but detoxification and elimination involve multiple systems including the gastrointestinal tract, kidneys and lymphatic system.
The gut-liver relationship is super interesting.
When you eat, drink or take medication, compounds absorbed through the intestinal wall enter the bloodstream. Much of this blood travels through the hepatic portal vein directly to the liver before returning to the general circulation.
This means the liver receives many compounds absorbed from the digestive tract and can then process, modify, store or prepare them for elimination.
Some compounds processed by the liver enter bile, which is released into the digestive tract. Meanwhile, your intestinal microbiome interacts with bile acids and influences what happens to them next.
Gut bacteria also produce metabolites that can cross the intestinal barrier and travel through the portal vein to the liver. This is part of the gut–liver axis: the gut influences what reaches the liver, while the liver sends certain compounds back to the gut through bile.
Dietary fibre can modify the gut environment, support microbial fermentation, influence stool transit and, depending on the type of fibre, affect bile acid excretion.
Which means one of the least sexy questions I ask in clinic is also one of the most useful:
How often are you opening your bowels?
Supporting detoxification isn't just about processing things, we also need an exit strategy.
www.healthonthehill.com.au