03/06/2026
Exercise may be one of the most powerful tools we have for healthy aging.
New research is looking at a protein called Klotho, often called the “anti-aging protein.” Klotho is found in organs such as the kidneys, brain, pancreas, and skin, and it appears to be involved in several important aging-related processes, including mitochondrial function, cellular health, and inflammation.
A 2026 review looked at 41 clinical trials involving 2,765 people aged 18 to 85 and found that exercise increased circulating soluble Klotho levels.
This included short-term exercise, medium-duration exercise, and longer-term exercise programs.
The most powerful message?
Consistent exercise over 12 weeks or more appeared to support Klotho levels across aerobic training, resistance training, and combined exercise programs.
This is another reminder that exercise is not just about weight loss.
It is a biological signal that tells your body to adapt, repair, strengthen, and become more resilient.
For healthy aging, focus on:
• Walking regularly
• Strength training 2–4 times per week
• Aerobic fitness
• Mobility
• Quality sleep
• Protein-rich, colourful meals
• Stress management
• Social connection
You do not need to train like an athlete to age well.
This included short-term, medium-duration, and long-term exercise programs.
But you do need to move consistently.