18/08/2026
Eosinophilic Otitis Media (EOM):
Why it matters: it looks like ordinary "resistant glue ear" but behaves completely differently — and misdiagnosis risks sudden, irreversible hearing loss.
What it is:A refractory otitis media caused by eosinophil-dominant middle ear fluid, driven by type 2 (allergic-pattern) inflammation rather than infection
Who gets it: More common in women; mean age of presentation is around 53 years — think of it in an older patient with "glue ear that won't quit"
Classic triad clue:Strongly associated with bronchial asthma (95% of patients) and nasal polyposis (71% of patients) — chronic rhinosinusitis in these patients also tends to be treatment-resistant
The trap:Standard treatments fail — ventilation tubes work in only 2% of cases, and antibiotic drops/myringoplasty have high failure rates
Danger sign:Higher risk of sensorineural hearing loss (gradual or sudden) than typical otitis media with effusion (OME) — don't dismiss it as "just glue ear"
Must exclude:Eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg–Strauss disease) — a vasculitis that can look identical early on
Best treatment: Intratympanic steroids (triamcinolone beats topical betamethasone) — success rate ~45%; systemic steroids ~26% success; biologics (omalizumab, mepolizumab, benralizumab, dupilumab) show the best results at 44–86% success