Therapeutic Approaches to Common Oral Diseases

Therapeutic Approaches to Common Oral Diseases Continuing Dental Education

The way you prepare fresh garlic has a significant impact on its health benefits. If you immediately place freshly chopp...
15/04/2026

The way you prepare fresh garlic has a significant impact on its health benefits. If you immediately place freshly chopped garlic into hot oil or hot foods, the heat destroys its ability to produce allicin, an important cancer-fighting compound.

To maximize its anticancer properties, you should simply chop the garlic and let it sit for 10 minutes before cooking it. During this resting period, the garlic generates copious amounts of allicin, and once this compound forms, it is no longer destroyed by later cooking.

31/03/2026

The Evolution of Recurrent Aphthous Stomatitis Management
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Research findings indicate that topical corticosteroids, hyaluronic acid, and low-level laser therapy are the most reliable options for reducing immediate pain and accelerating the healing of mouth ulcers. While herbal remedies like aloe vera and honey show promise for short-term relief, systemic medications such as colchicine or thalidomide are reserved strictly for severe cases due to their potential side effects.

While many treatments manage symptoms effectively, high-quality evidence regarding the prevention of future recurrences remains limited.

“Is 3.6-mL volume of an anesthetic agent more effective than 1.8-mL volume in providing anesthesia for mandibular molars...
23/03/2026

“Is 3.6-mL volume of an anesthetic agent more effective than 1.8-mL volume in providing anesthesia for mandibular molars?”

For patients with irreversible pulpitis , research indicates that increasing the volume of the anesthetic agent from 1.8 mL to 3.6 mL significantly improves the success rate of an inferior alveolar nerve block (IANB).

While 1.8 mL is a standard dose, studies on teeth with irreversible pulpitis have shown the following regarding the two volumes:

Success Rates: The success rate of 1.8 mL has been reported to be as low as 14.8% to 27.5%. Doubling that volume to 3.6 mL increased success rates to a range of 39.3% to 77.5%.

Effectiveness: A meta-analysis of these findings determined that 3.6 mL is 2.45 times more likely to result in successful anesthesia than 1.8 mL in these cases.

Biological Basis: The theory for this improvement is that a larger volume fills the pterygomandibular space more thoroughly, exposing a greater length of the nerve trunk to the anesthetic agent. This is particularly important for inflamed pulps, where nerves often have altered resting potentials and a reduced threshold for excitability.

Important Considerations for Clinical Practice:

Despite the improved performance of the 3.6-mL dose, the sources highlight that the overall success rate for achieving profound anesthesia in these teeth remains low. Even with larger volumes, the "hot tooth" is notoriously difficult to anesthetize, and supplemental anesthetic techniques—such as buccal infiltrations, intraligamental injections, or intraosseous injections—are frequently required to ensure a completely pain-free endodontic procedure.

Additionally, these findings specifically apply to mandibular molars; the sources suggest caution when generalizing these volume requirements to other teeth or using anesthetic agents other than lidocaine and articaine.

Source: https://lnkd.in/gU-2TJ_A

Sodium lauryl sulfate (SLS)–free dentifrice reduces symptoms of recurrent aphthous stomatitis (RAS).SLS is a surfactant ...
12/11/2025

Sodium lauryl sulfate (SLS)–free dentifrice reduces symptoms of recurrent aphthous stomatitis (RAS).

SLS is a surfactant that can irritate mucosa and strip protective mucous layers, which may predispose susceptible patients to mucosal breakdown and aphthae; removal of this irritant is biologically plausible as a preventive measure.

Systematic review concluded that replacing an SLS-containing toothpaste with an SLS-free alternative is associated with improvements in ulcer pain, healing time, and — in some studies — reduced ulcer frequency.

DOI: 10.1111/jop.12845

Salt water mouthwash, at certain concentrations, is an effective and well-tolerated alternative to 0.1% Chlorhexidine. *...
28/10/2025

Salt water mouthwash, at certain concentrations, is an effective and well-tolerated alternative to 0.1% Chlorhexidine.

* Most Effective & Comparable Option: The 5.8% saline solution has an antibacterial efficacy similar to the commonly prescribed 0.1% Chlorhexidine.

Both of these solutions reduced the oral flora significantly for 5 hours.

* Good Short-Term Option: Homemade 2% saline (the most common and best-tolerated) can be prescribed for short-term indications as its antibacterial action lasts for 3 hours.

Green Tea and Oral Lichen Planus_________________________________Oral lichen planus (OLP) is a common T-cell-mediated in...
09/06/2023

Green Tea and Oral Lichen Planus
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Oral lichen planus (OLP) is a common T-cell-mediated inflammatory autoimmune disease with the features of disease chronicity, adult onset, female predilection and depressed immune suppressor activity.

Study results demonstrate that green tea can inhibit antigen presentation, T-cell activation, proliferation and migration, keratinocyte apoptosis, nuclear factor-kappaB activation and MMP-9 activation in the pathogenesis of oral lichen planus.

Epigallocatechin-3-gallate (EGCG) of green tea possesses anti-inflammatory and chemopreventive properties.

Hence green tea, especially EGCG, is likely to be a suitable therapeutic candidate for OLP. Green tea might be also a possible agent for preventing malignancies in OLP.

Zhang, J., & Zhou, G. (2012). Green tea consumption: an alternative approach to managing oral lichen planus. Inflammation Research, 61(6), 535–539. https://doi.org/10.1007/s00011-012-0440-z

Candida superinfection occurs in approximately one-third of patients with oral lichen planus (OLP) or oral lichenoid rea...
09/05/2023

Candida superinfection occurs in approximately one-third of patients with oral lichen planus (OLP) or oral lichenoid reactions (OLR) undergoing corticosteroid therapy. Patients with OLP/OLR should be closely monitored in the first 2 months (60 days) after steroid prescription.

Toothpaste containing extra virgin olive oil, xylitol, and betaine may improve gingival health; however, more studies ar...
04/05/2023

Toothpaste containing extra virgin olive oil, xylitol, and betaine may improve gingival health; however, more studies are needed.

Oleocanthal is a phenolic compound obtained in just-pressed extra virgin olive oil (EVOO), and its structure was found in an in vitro study to be similar to that of ibuprofen (non-steroidal anti-inflammatory drug). Oleocanthal has a greater capacity to inhibit both cyclooxygenases (COX-1 and COX-2) in comparison to ibuprofen at the same concentrations.

The test toothpaste also contains xylitol, which has been found to inhibit the synthesis of TNF-α and IL-1β induced by lipopolysaccharides from Porphyromonas gingivalis through NF-κB pathway activation.

The EVOO phenols and xylitol in the test toothpaste may therefore have combined effects on gingival bleeding.

PMID: 37072503

Few facts of herpes labialis___________________________** Herpes labialis is caused by the herpes simplex virus type 1 (...
26/04/2023

Few facts of herpes labialis
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** Herpes labialis is caused by the herpes simplex virus type 1 (HSV-1) and is a very common infection. It is estimated that up to 80% of people will have been exposed to the virus at some point in their lives.

** The virus is highly contagious and is transmitted through direct contact with an active lesion or through contact with saliva or ge***al secretions of an infected person.

** Symptoms of herpes labialis typically include tingling, burning, or itching sensations on or around the lips, followed by the appearance of small, fluid-filled blisters that can be painful and may take several days to heal.

** There is no cure for herpes labialis, but antiviral medications such as acyclovir, valacyclovir, and famciclovir can help to reduce the duration and severity of symptoms.

** Recurrent outbreaks of herpes labialis are common, with some people experiencing multiple episodes per year. Outbreaks can be triggered by factors such as stress, illness, sun exposure, and hormonal changes.

** It is possible to transmit the virus to others even when there are no visible symptoms present, a condition known as asymptomatic shedding. Therefore, people with herpes labialis should take precautions to avoid spreading the virus, such as avoiding close contact with others during outbreaks, using condoms during sexual activity, and refraining from sharing personal items such as towels and utensils.

** While herpes labialis is generally considered to be a mild infection, it can cause serious complications in people with weakened immune systems, such as those with HIV/AIDS or undergoing chemotherapy. In rare cases, the virus can also cause encephalitis, a serious inflammation of the brain.

Few facts about aphthous stomatitis:____________________________________** Aphthous stomatitis, commonly known as canker...
25/04/2023

Few facts about aphthous stomatitis:
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** Aphthous stomatitis, commonly known as canker sores, is a prevalent condition affecting around 20% of the population.

** The exact etiology of aphthous stomatitis is still unknown; however, it's believed to be related to genetic, immune system, and environmental factors.

** The clinical manifestation of aphthous stomatitis includes small, painful, round or oval-shaped ulcers with a white or yellow center and red border, typically located inside the mouth, such as the tongue, lips, and cheeks.

** Aphthous stomatitis is not contagious.

** Certain foods, stress, hormonal changes, and trauma to the mouth may trigger aphthous stomatitis.

** The initial management of aphthous stomatitis involves symptomatic treatment with over-the-counter pain relievers, topical anesthetics, and oral rinses.

** In severe cases, prescription medications such as corticosteroids or immunomodulators may be necessary.

** There is no definitive cure for aphthous stomatitis, but symptoms typically improve on their own within a few days to a couple of weeks.

** Aphthous stomatitis is not associated with an increased risk of oral cancer.

** Good oral hygiene, avoiding trigger foods, and stress management can help reduce the frequency and severity of outbreaks in people with frequent or severe aphthous stomatitis.

**Vitamin B12 deficiency may be linked with aphthous stomatitis, and supplementation may help reduce the frequency and severity of outbreaks.

** Probiotics are being studied as a potential preventive or therapeutic option for aphthous stomatitis.

** In rare cases, aphthous stomatitis may be a manifestation of underlying systemic diseases, such as Crohn's disease or celiac disease.

** If you experience frequent or severe canker sores, it's recommended to consult with a healthcare professional to rule out underlying medical conditions and explore treatment options.

** Proper management of aphthous stomatitis can improve quality of life and reduce the impact of symptoms on daily activities.

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