06/28/2025
Sovaldi (sofosbuvir) is a direct-acting antiviral medication that works by blocking the hepatitis C virus (HCV) from multiplying in your body. By targeting a key viral enzyme, Sovaldi helps reduce the viral load to undetectable levels, giving your immune system a chance to clear the infection.
This prescription drug is used—always in combination with other antivirals such as ribavirin, with or without peginterferon alfa—to treat chronic hepatitis C in adults and children aged three years and older. It’s effective against specific HCV genotypes (1, 2, 3, and 4) and may also be prescribed for patients coinfected with HIV or those awaiting a liver transplant due to HCV-related disease.
Thanks to its targeted action and shorter treatment durations, Sovaldi has transformed the outlook for many people living with hepatitis C.