04/30/2026
https://www.facebook.com/share/p/14aMShhPCrW/
Carbon dioxide heals wounds.
In a trial with people who had chronic diabetic wounds, 2/3 wounds healed with CO2 gas. In the control group, exposed to air instead of CO2, none healed.
The procedure was to wrap the wounded area in plastic, pump out the air, and pump pure CO2 gas into the sealed bag. It lasted 45 minutes per session.
“The results of our research confirmed that transcutaneous application of gaseous COz significantly improved the healing of chronic wounds in diabetic patients. Wounds in study group patients that received CO2 therapy healed significantly faster compared with the control group (Table 2). After CO2 therapy, 66% of the wounds healed completely compared with 0% in the placebo group.”
CO2 is produced in mitochondria during respiration and is often referred to as a waste product of energy production, but its perfusion into tissues has significant health benefits. Blood CO2 is tightly regulated and is not a great indicator here.
The oxidation of glucose under the influence of thyroid hormone T3 is required for optimal mitochondrial CO2 production, affecting rate and quantity. This is why diabetes and hypothyroidism are associated with poor wound healing.
“A substantial body of research links hypothyroidism to impaired wound healing, with one of the most critical mechanisms being disruption of angiogenesis. Angiogenesis is essential during the proliferative phase of wound repair, as it ensures adequate oxygen delivery, nutrient transport, and recruitment of cells required for tissue regeneration. In hypothyroidism, this process is significantly impaired, consistent with the generalized metabolic slowdown seen in the condition.”
CO2 is readily absorbed through the skin, and so the effect of transcutaneous application is similar to that of optimal metabolism.
Ref:
The effect of transcutaneous application of gaseous CO2 on diabetic chronic wound healing-A double-blind randomized clinical trial
Effects of Thyroid Dysfunction on Angiogenesis During Wound Healing and Skin Repair: A Systematic Review
[Image] A Novel System for Transcutaneous Application of Carbon Dioxide Causing an “Artificial Bohr Effect” in the Human Body
