Saguaro Biosciences

06/02/2026

🌵 ✨ Setting up 3D assays for the highest-quality data possible: Get our 3D technical note here ✨ 🌵

3D cell models offer superior biological accuracy, but technical barriers like toxic "live" dyes, poor dye pe*******on, and clearing reagents often destroy important information and introduce bias.

Our latest technical note solves this with a streamlined workflow using ChromaLIVE™ and NucleoLIVE™.

🌟 Simple, mix-and-read protocol: Deep and uniform pe*******on without fixation or clearing reagents.
🌟 Capture temporal changes: Track phenotypic shifts in an unperturbed physiological state.
🌟 Accurate 3D profiling: Robust nuclear staining enables precise 3D single-cell segmentation.
🌟 Scalable outputs: Optimized for high-content systems for scalable and reproducible data.

👉 Download the technical note here: https://zurl.co/XB4z6

05/26/2026

🌵✨Elevating live-cell profiling: Introducing the ChromaLIVE+™ series ✨🌵

Everything you love about ChromaLIVE™ —non-toxic, mix-and-read, and high-fidelity—now with an added layer of information to supercharge your profiling performance.

Building on our core ChromaLIVE™ technology, we are excited to introduce the ChromaLIVE+™ series. We’ve combined the market’s leading live-cell profiling dye with our organelle-specific markers to deliver deeper biological insights—without ever perturbing your cells.

ChromaLIVE+™ enhances overall profiling performance with improved bioactivity detection and increased phenotypic distinctiveness. And we found that ChromaLIVE™ with ER-LIVE™ or with LipoLIVE™ have the biggest impact on that performance!

🚀 ChromaLIVE+ER™
🚀 ChromaLIVE+Lipo™

Learn more at : https://zurl.co/xMSRc or reach out to us at [email protected].

04/23/2026

🌵✨ One Dye, Four Measurements✨🌵

Relying on endpoint snapshots that limit your data quality? It's time to upgrade your assay panel to a more versatile, "all-in-one" approach.

With MortaLIVE™, our non-toxic, live-cell dye, you can reveal drug-specific responses in both 2D and 3D systems that are simply not detectable with traditional end point readouts like CTG, LDH or resazurin staining.

Get 4 measurements with a single-step, mix and read protocol:

🔴 Cytotoxicity 🟢 Viability ⚡ Stress ⏸️ Cytostatic

Want more? combine with NucleoLIVE™ and track

🔶 Cell cycle progression 🔷 Proliferation—giving you 6 critical measurements using just 2 dyes!

👉 See the data in our latest poster: https://zurl.co/CfRK3

📧 Reach out to us at [email protected] or learn more at https://zurl.co/IY8Al

04/21/2026

🌵✨Simplifying and boosting toxicity assessments of Neural organoids with MortaLIVE ✨🌵

We are thrilled to showcase the work of our collaborator at Hopkins Center for Alternatives to Animal Testing (CAAT) on iPSC derived neural organoids.

The work highlighted how MortaLIVE enables,

🌟 Replace multiple viability and morphological assays with a simple, mix-and-read stain, providing the scalability and precision required for neurotoxicity assessments.

🌟 Achieving high-resolution morphological insights and viability quantification from the same sample, without compromising cell health and sample integrity.

🌟 Obtaining the unperturbed and biologically relevant data necessary for to advance toxicology assessments in complex in vitro models.

📑 Access the full poster here: https://zurl.co/Qd96c

A huge thank you to Smirnova and , for presenting this incredible poster at the of Toxicology (SOT) ToxExpo 2026.

04/14/2026

🌵✨Launching LipoLIVE Deep Red✨🌵

We are thrilled to announce a new color for LipoLIVE™, the breakthrough fluorescent probe for real-time visualization of lipid dynamics in living cells.

It maintains the same physiological integrity as LipoLIVE Green, making it the ideal partner for , , and studies.

Why choose LipoLIVE™?

👉 Seamless integration: A one-step, no-wash dye that remains in the culture medium throughout the assay for multi-day, high-content discovery.

👉 True biological fidelity: Monitor processes like lipid synthesis, storage, and mobilization without perturbing cell health—essential for long-term lipid droplet tracking.

👉 Multiplex-ready: Designed to pair perfectly with our ChromaLIVE™ and NucleoLIVE™ for improved live-cell, phenotypic profiling performance.

Reach out to us at [email protected] or learn more at https://zurl.co/Xpc9f

04/02/2026

[English Follows]

Activité d’équipe printanière 🌸🧠

La semaine dernière, notre équipe s’est réunie pour célébrer l’arrivée du printemps avec une activité amusante : le Quiz Room ! Répartis en équipes, nous avons mis nos connaissances (et notre esprit de compétition) à l’épreuve dans une ambiance de jeu télévisé pleine de surprises, de rires… et de quelques vols de points stratégiques 👀🏆

Nous avons ensuite poursuivi la soirée dans un restaurant mexicain pour savourer de délicieux plats 🌮🍹

Un grand merci à toute l’équipe Saguaro pour son énergie et sa bonne humeur. 🌸🌵

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Spring Team Activity 🌸🧠

Last week, our team got together to celebrate the arrival of spring with a fun activity: the Quiz Room! Split into teams, we put our knowledge (and competitive spirit) to the test in a game-show atmosphere full of surprises, laughs… and a few strategic point steals 👀🏆

We then headed to a Mexican restaurant to wrap up the evening with delicious food 🌮🍹

A big thank you to the entire Saguaro team for bringing such energy and positivity. Here’s to a vibrant and successful spring ahead! 🌸🌵

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03/26/2026

Featured in the news this morning! 📍

We’re proud to see Saguaro Biosciences highlighted today for our work in transforming drug discovery with our live cell profiling technologies.

At Saguaro, we believe that the best way to decode cell biology is to watch it happen—live and unperturbed. Today’s feature in La Presse explores how we’re making that vision a reality for labs worldwide.

Proud of our team and thankful for the local support as we continue to grow. We are just getting started! 🚀

To read the article: https://zurl.co/Pqtxg[…]m_source=lpp&utm_medium=referral&utm_campaign=internal+share

Saguaro Biosciences développe des colorants cellulaires non toxiques qui permettent aux chercheurs en médecine d’observer les cellules en temps réel et de générer des données d’une grande richesse pour faciliter et accélérer la mise au point de nouveaux médicaments. Portrait.

03/10/2026

SOT ToxExpo: Why bother using complex in vitro models if you can’t capture high-fidelity data from them? 🤔

Imaging is a key readout for meaningful toxicity data, but current probes (so-called for “live cells”) disturb cells because they are in fact toxic or require washing and fixation. They also do not pe*****te 3D cultures, leaving them inconsistently stained.🚫

From enriched cell health data with simple assays, to the leading technology for profiling drugs/cells/perturbations with images, come see how we make high-fidelity discovery possible with deep, reproducible, and non-toxic imaging. 🧬🔬

Stop by our poster and booth! 🌵

📍 Booth #2304 (Yokogawa will be hosting me at their booth!)
📅 Poster on Tuesday!

Be sure to reach out to book some time together👇
[email protected]

02/24/2026

🌵✨LipoLIVE™ : Get your Launch discount now✨🌵

We are super excited to announce the launch of LipoLIVE™, a breakthrough fluorescent probe for the real-time visualization of lipid dynamics in living cells.

Unlike traditional dyes, it maintains physiological integrity, making it the ideal partner for , , and studies.

Why choose LipoLIVE™?

👉 Seamless Integration: A one-step, no-wash dye that remains in the culture medium throughout the assay for multi-day high-content discovery.

👉 True Biological Fidelity: Monitor lipid synthesis, storage, and mobilization without perturbing cell health.

👉 Robust Performance: Exceptional signal-to-noise ratios and photostability for seamless high-content screening (HCS) workflows.

💥 Special Launch Offer 💥

Get your first tube at 15% off. Buy again within 30 days to get 25% off your second order

📧 Reach out to us at: [email protected] to claim your special launch offer! 🎁

02/17/2026

🌵✨ That’s a wrap on an incredible ! ✨ 🌵

It was fantastic to connect with our clients and partners at (Society for Laboratory Automation and Screening) conference in Boston.

A huge shoutout to Mathien for his presentation on the power of Live-Cell Painting! He showcased data from a 3,000+ compound screen, proving that ChromaLIVE™ captures dynamic, biologically accurate insights that traditional cell painting and brightfield miss.

Special thanks to our collaborators , Pinerio-Llanes, and Simpson for their presentations showcasing Saguaro dyes.

We were proud to present our latest data on:

👉 Revealing mechanisms of cytotoxicity: Using MortaLIVE™ and NucleoLIVE™ to distinguish distinct cell death pathways. (https://zurl.co/GzM7m )
👉 Real-time toxicity assessment: Supporting the regulatory adoption of organoids with kinetic, non-toxic data. (https://zurl.co/Tw3tz )
👉 Boosting cell painting performance: Demonstrating a physiologically relevant alternative to commercial endpoint assays.(https://zurl.co/L8owL )

📧 Missed us at the event? Let's keep the conversation going, reach out to us at [email protected].