13/06/2020
Our new tool to visualise mutations that arise from copying damaged DNA has been published in Biomolecules https://www.mdpi.com/2218-273X/10/6/902. The paper reports results of the PhD project of Marta Rodriguez
The sustainment of replication and transcription of damaged DNA is essential for cell survival under genotoxic stress; however, the damage tolerance of these key cellular functions comes at the expense of fidelity. Thus, translesion DNA synthesis (TLS) over damaged nucleotides is a major source of p...