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Could Omega-3 + Low-Dose Aspirin Rival Antibiotics in Severe Periodontitis?A new randomized, multicenter, double-blind c...
28/08/2026

Could Omega-3 + Low-Dose Aspirin Rival Antibiotics in Severe Periodontitis?

A new randomized, multicenter, double-blind clinical trial suggests a potentially important approach to Stage III–IV periodontitis: targeting inflammation rather than relying solely on antibiotics.

All 109 participants received subgingival instrumentation and were then assigned to placebo or adjunctive treatment with antibiotics, Omega-3 + low-dose aspirin (ASA), or a combination of both.

📊 The key finding: After 1 year, 58.6% of patients receiving antibiotics reached the defined treatment endpoint. Remarkably, 57.7% of patients receiving Omega-3 + low-dose aspirin reached the same endpoint. With instrumentation + placebo alone, the figure was only 23.1%.

The Omega-3/ASA regimen used in the study was 3 g Omega-3 daily + 100 mg ASA daily for 6 months. The antibiotic group received 500 mg amoxicillin + 400 mg metronidazole three times daily for 14 days.
⚠️ Important: This does not mean patients should replace prescribed antibiotics or start taking aspirin and high-dose Omega-3 on their own. The researchers suggest the approach could potentially become an alternative for selected patients who cannot take antibiotics, but further studies are required before it can be considered a routine substitute. Aspirin also carries clinically relevant risks and contraindications.

Bottom line: Periodontal therapy may increasingly be about more than controlling bacteria — controlling and resolving inflammation could become an equally important therapeutic target.

📚 Santos NC Castro dos et al. (2026). DOI: 10.1002/jper.70081

GLP-1 medications such as Ozempic and Wegovy have transformed weight management — but researchers are still learning wha...
26/08/2026

GLP-1 medications such as Ozempic and Wegovy have transformed weight management — but researchers are still learning what long-term, rapid weight loss may mean for the rest of the body.

A large retrospective study involving nearly 150,000 patients reported an association between GLP-1 medication use and several musculoskeletal conditions over a five-year period.

The researchers reported approximately:

+30% higher risk of osteoporosis
+12% higher risk of gout
and an increased incidence of osteomalacia, a condition involving impaired bone mineralization.

So what could this mean for dentistry?

Teeth don’t exist independently from the rest of the body. They are anchored in the alveolar bone, and maintaining healthy bone metabolism is an important part of maintaining periodontal support.

Periodontitis itself is a complex inflammatory disease caused primarily by a dysbiotic bacterial biofilm and the body’s inflammatory response. This study does NOT show that Ozempic causes periodontitis or tooth loss.

But it raises an interesting clinical question:

If systemic bone health, nutritional status or muscle mass are adversely affected during substantial weight loss, could this also matter for patients who already have compromised periodontal tissues or other risk factors for bone loss?

Rapid weight reduction can also make adequate intake of protein, calcium, vitamin D and other micronutrients more important — particularly when appetite is substantially reduced.

For dentists, this is another reason to look beyond the teeth.

Ask about medications.
Ask about major weight changes.
Look at periodontal health.
Consider nutrition and systemic risk factors.
And remember that oral health is connected to whole-body health.

⚠️ Important: Association does not equal causation. The available observational data cannot establish that GLP-1 drugs directly cause osteoporosis, periodontal disease or tooth loss. Other research on GLP-1 drugs and fracture/bone outcomes has produced mixed results.

Source: Large retrospective cohort study presented at the American Academy of Orthopaedic Surgeons (AAOS) Annual Meeting 2026, involving nearly 150,000 patients.

🚨 YOUR MOUTH COULD REVEAL A SEXUALLY TRANSMITTED INFECTION.Yes — you read that right.When most people think of chlamydia...
25/08/2026

🚨 YOUR MOUTH COULD REVEAL A SEXUALLY TRANSMITTED INFECTION.

Yes — you read that right.

When most people think of chlamydia, gonorrhea, syphilis, herpes, HPV or HIV, they probably don’t think of their dentist.

But they should.

Certain sexually transmitted infections can cause visible changes inside the mouth — including ulcerations, warts, oral candidiasis and characteristic mucosal lesions.

And this is not some obscure dental theory.

The FDI World Dental Federation has highlighted the oral manifestations of sexually transmitted infections and the role dental professionals may play in recognizing suspicious signs and referring patients for further evaluation.

Think about that for a second:

👉 A routine look inside your mouth could reveal a clue that deserves investigation elsewhere in your body.

That does not mean a dentist can diagnose an STI simply by looking at your mouth. Many oral changes have completely different causes.

But it does mean something incredibly important:

YOUR MOUTH TALKS.

And if you know how to listen, it can tell you much more than whether you have a cavity.

This is exactly why I believe we need to stop treating teeth as isolated pieces of enamel.

Your mouth is part of your body.
Your oral tissues are part of your health.
And prevention starts with paying attention.

🦷 This bigger perspective on oral health is also at the heart of my book Anti-Tooth-Aging: understanding your mouth, protecting your teeth for the long term and recognizing why oral health deserves far more attention than simply brushing twice a day.

Your dentist may see things you would never notice yourself.

That alone is a pretty powerful reason not to skip your next check-up.

Save this. Share it. And next time you look in the mirror, remember:

Your mouth may be telling you more than you think.

NAD⁺: What the Evidence Actually Shows (sorry for everyone who thinks that he/she/it will get younger by using NAD+) NR ...
22/08/2026

NAD⁺: What the Evidence Actually Shows (sorry for everyone who thinks that he/she/it will get younger by using NAD+)

NR and NMN reliably increase NAD⁺ biomarkers — in some studies, blood NAD⁺ rises by around 50%.

But higher NAD⁺ does not currently mean proven better health.

A 2026 systematic review covering 33 human studies, including 28 randomized trials, found that while NR and NMN consistently raise NAD-related biomarkers, actual health benefits remain inconsistent or often absent — including effects on metabolism, cardiovascular function, physical performance, and other healthspan outcomes.

Bottom line: Higher NAD⁺ is proven. A meaningful anti-aging or health benefit in healthy humans is not - even though celebrities try to sell it that way. It’s just not the reality.

⚠️Side-Effects: At doses around 300 mg/day, no consistent serious adverse effects have emerged. Reported effects can include mild nausea, stomach/GI discomfort, headache, fatigue, or flushing, but these have not consistently occurred more often than with placebo.
The bigger uncertainty is long-term use. We do not yet have strong safety data for healthy people taking NR every day for many years. NR also increases breakdown products such as nicotinamide and methylated metabolites, but the clinical significance of this with long-term supplementation remains unclear.

Start eating healthy food and move your ass - that’s a proven Anti-Aging therapy with a strong evidence.

29/07/2026

Every now and then, I still perform simple aesthetic restorations for children when needed—always with the same precision and quality.

21/07/2026

An amazing case! Solving a really severe crowding without any extractions! This is how Aligner cases can look like today! No club!

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