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APS Support UK - for people with antiphospholipid syndrome

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APS Support UK - for people with antiphospholipid syndrome

APS Support UK is a national UK charity dedicated to anyone affected by antiphospholipid syndrome

Antiphospholipid syndrome (APS) is an autoimmune condition in which there is an increased tendency for the blood to clot. The clotting can affect any organ in the body and the consequences can include potentially fatal conditions such as heart attacks, strokes, pulmonary emboli and DVTs. In pregnancy, APS is the most common treatable form of recurrent miscarriage, it can also cause infertility and

stillbirths. APS Support UK (the trading name of the Hughes Syndrome Foundation) became a registered charity in 2001. We aim to support anyone affected by the condition; to raise awareness of the disease both among the general public and the medical community; and to raise funds to provide information, education and further medical research.

04/09/2026

🧠 𝗖𝗼𝘂𝗹𝗱 𝘁𝗵𝗲 𝗹𝗲𝘃𝗲𝗹 𝗼𝗳 𝗽𝗲𝗿𝘀𝗶𝘀𝘁𝗲𝗻𝘁 𝗮𝗻𝘁𝗶𝗽𝗵𝗼𝘀𝗽𝗵𝗼𝗹𝗶𝗽𝗶𝗱 𝗮𝗻𝘁𝗶𝗯𝗼𝗱𝗶𝗲𝘀 𝗵𝗲𝗹𝗽 𝘁𝗲𝗹𝗹 𝘂𝘀 𝗺𝗼𝗿𝗲 𝗮𝗯𝗼𝘂𝘁 𝘀𝘁𝗿𝗼𝗸𝗲 𝗿𝗲𝗰𝘂𝗿𝗿𝗲𝗻𝗰𝗲?

A new study followed 47 people who had experienced a cryptogenic stroke or TIA and continued to test positive for antiphospholipid antibodies (aPLs) for at least 12 weeks.

Researchers found that recurrent ischaemic stroke was less common in people with weakly positive aPLs than in those with strongly positive aPLs.

Treatment patterns also differed: antiplatelet medicines were recommended more often in the weakly positive group, while warfarin was more commonly recommended for those with strongly positive aPLs.

It’s an interesting finding, but the study was small, retrospective and carried out within one health system. The researchers say larger prospective studies and randomised trials are needed to better understand the best treatment approach.

🔗 Read the study: https://pubmed.ncbi.nlm.nih.gov/42668533/

03/09/2026

𝗧𝗵𝗶𝗻𝗸𝗶𝗻𝗴 𝗮𝗯𝗼𝘂𝘁 𝘁𝗮𝗸𝗶𝗻𝗴 𝗽𝗮𝗿𝘁 𝗶𝗻 𝗦𝗼𝗯𝗲𝗿 𝗦𝗲𝗽𝘁𝗲𝗺𝗯𝗲𝗿? 🍹🚫

Why not turn your challenge into a fundraiser for APS Support UK at the same time?

Going alcohol-free for the month can be a great personal challenge — and by asking friends, family and colleagues to sponsor you, you can also help us raise awareness of antiphospholipid syndrome (APS) and support our work.

You can set up your own fundraising page through our JustGiving page, and we can also provide sponsorship forms and leaflets if needed.

Find out more and get started here:
https://aps-support.org.uk/get-involved/help-us-fundraise/sober-september

02/09/2026

🔬 𝗡𝗲𝘄 𝗨𝗞 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗶𝗻𝘁𝗼 𝗔𝗣𝗦 𝘁𝗲𝘀𝘁𝗶𝗻𝗴 𝗮𝗳𝘁𝗲𝗿 𝗮𝗻 𝘂𝗻𝗲𝘅𝗽𝗹𝗮𝗶𝗻𝗲𝗱 𝗯𝗹𝗼𝗼𝗱 𝗰𝗹𝗼𝘁

A new multicentre study has looked at how antiphospholipid syndrome (APS) is identified following an unprovoked venous thromboembolism (VTE) — a DVT or pulmonary embolism occurring without a major provoking factor.

Researchers analysed 897 patients across five UK thrombosis centres.

APS was diagnosed in 11.7% of the overall cohort. At the centre where everyone was tested for antiphospholipid antibodies, APS was identified in 15.8% of patients, compared with 5.8% across the centres using selective testing.

The researchers also found that individual clinical features used to help decide who should be tested were poor predictors of APS.

The findings raise important questions about how best to identify APS following an unprovoked blood clot. However, the authors stress that further prospective research is needed before the optimal testing strategy can be established.

🔗 Read the full study: https://linkinghub.elsevier.com/retrieve/pii/S1538783626002886

01/09/2026

A new systematic review has looked at how well the 𝟮𝟬𝟮𝟯 𝗔𝗖𝗥/𝗘𝗨𝗟𝗔𝗥 𝗰𝗹𝗮𝘀𝘀𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗰𝗿𝗶𝘁𝗲𝗿𝗶𝗮 𝗳𝗼𝗿 𝗮𝗻𝘁𝗶𝗽𝗵𝗼𝘀𝗽𝗵𝗼𝗹𝗶𝗽𝗶𝗱 𝘀𝘆𝗻𝗱𝗿𝗼𝗺𝗲 (𝗔𝗣𝗦) perform across different groups of people with APS.

Researchers reviewed 24 studies, covering 25 datasets. Overall, the criteria showed very high specificity (99%), but sensitivity varied depending on the type of APS.

Sensitivity was particularly lower in obstetric APS than in thrombotic APS. Obstetric APS and isolated IgM antiphospholipid antibody positivity were also among the main reasons some people were not classified by the newer criteria.

Importantly, the 2023 ACR/EULAR criteria were developed for research classification — not for diagnosing an individual patient. The findings reinforce why classification criteria and clinical diagnosis should not be treated as the same thing.

🔗 Read the study: https://pubmed.ncbi.nlm.nih.gov/42615990/

27/08/2026

🧬 𝗖𝗼𝘂𝗹𝗱 𝗱𝗶𝗳𝗳𝗲𝗿𝗲𝗻𝘁 𝗽𝗲𝗼𝗽𝗹𝗲 𝘄𝗶𝘁𝗵 𝗔𝗣𝗦 𝗵𝗮𝘃𝗲 𝗱𝗶𝗳𝗳𝗲𝗿𝗲𝗻𝘁 𝘂𝗻𝗱𝗲𝗿𝗹𝘆𝗶𝗻𝗴 𝗺𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗽𝗮𝘁𝘁𝗲𝗿𝗻𝘀?

New research has explored the immune pathways involved in antiphospholipid syndrome (APS), identifying two areas of particular interest: type I interferon signalling and changes in the behaviour of certain B cells.

The researchers suggest these molecular differences could one day help scientists better understand why APS varies so much from person to person — and potentially support more targeted approaches to treatment in the future.

Importantly, this was a computational research study, not a clinical trial, and the potential treatment targets identified still need laboratory and clinical testing.

It’s an interesting step towards understanding the biology behind APS in greater detail.

🔗 Read the study: https://pubmed.ncbi.nlm.nih.gov/42647509/

26/08/2026

👕 𝗖𝗹𝗲𝗮𝗿𝗶𝗻𝗴 𝗼𝘂𝘁 𝘆𝗼𝘂𝗿 𝘄𝗮𝗿𝗱𝗿𝗼𝗯𝗲? 𝗬𝗼𝘂𝗿 𝗽𝗿𝗲-𝗹𝗼𝘃𝗲𝗱 𝗰𝗹𝗼𝘁𝗵𝗲𝘀 𝗰𝗼𝘂𝗹𝗱 𝗵𝗲𝗹𝗽 𝘀𝘂𝗽𝗽𝗼𝗿𝘁 𝗔𝗣𝗦 𝗦𝘂𝗽𝗽𝗼𝗿𝘁 𝗨𝗞. 💙

Through Thrift+, you can send in unwanted clothing to be resold and choose to support APS Support UK through the PayPal Giving Fund.

It’s a simple way to give your clothes a second life while helping us continue our work supporting people affected by antiphospholipid syndrome (APS).

Find out more and start your clear-out here: thrift.plus/clearout

24/08/2026

🧬 𝗔𝘂𝘁𝗼𝗶𝗺𝗺𝘂𝗻𝗲 𝗰𝗼𝗻𝗱𝗶𝘁𝗶𝗼𝗻𝘀 𝗱𝗼𝗻’𝘁 𝗮𝗹𝘄𝗮𝘆𝘀 𝗼𝗰𝗰𝘂𝗿 𝗶𝗻 𝗶𝘀𝗼𝗹𝗮𝘁𝗶𝗼𝗻.

A recent case report describes a 40-year-old woman who was diagnosed with four different autoimmune diseases affecting her digestive system, liver and bile ducts.

While this particular case does not involve antiphospholipid syndrome (APS), some people with APS also live with other autoimmune conditions.

Lupus is particularly closely associated with APS, while links have also been reported with conditions including rheumatoid arthritis, coeliac disease, Sjögren’s syndrome and autoimmune thyroid disease.

Read the article here: https://www.gazetaexpress.com/en/Rare-medical-case%3A-40-year-old-woman-diagnosed-with-four-autoimmune-diseases/

Find out more about conditions related to APS on our website:
https://aps-support.org.uk/about-aps/related-conditions

21/08/2026

🏃‍♂️ 𝗥𝗶𝗰𝗵𝗮𝗿𝗱 𝗶𝘀 𝘁𝗮𝗸𝗶𝗻𝗴 𝗼𝗻 𝗵𝗶𝘀 𝗳𝗶𝗿𝘀𝘁 𝗵𝗮𝗹𝗳 𝗺𝗮𝗿𝗮𝘁𝗵𝗼𝗻 𝗳𝗼𝗿 𝗔𝗣𝗦 𝗦𝘂𝗽𝗽𝗼𝗿𝘁 𝗨𝗞! 💙

On 27 September, Richard will be running the Robin Hood Half Marathon to raise awareness of antiphospholipid syndrome (APS) and support our work.

After Sonia was diagnosed with APS following a DVT, Richard and Sonia experienced first-hand just how life-changing this little-known autoimmune condition can be.

Last year, their incredible fundraising raised £𝟭,𝟬𝟮𝟮 — and Richard is hoping our community can help him do it again! 🙌

A huge thank you, Richard, for taking on this challenge and helping to raise vital awareness of APS.

💙 If you can, please donate to Richard’s fundraiser: https://www.justgiving.com/page/rich-3

And if you’re unable to donate, sharing this post can make a real difference too. Please help us cheer Richard on and spread the word! 👏

20/08/2026

🚨 𝗛𝗘𝗟𝗣 𝗔𝗣𝗦 𝗦𝗨𝗣𝗣𝗢𝗥𝗧 𝗨𝗞 𝗪𝗜𝗡 £𝟱,𝟬𝟬𝟬! 💙

There’s a really easy way you can support APS Support UK this week — and it won’t cost you anything extra.

Sign up to support APS Support UK on easyfundraising by Sunday 23rd August and you’ll give us a FREE entry into their £5,000 Donation Day giveaway, sponsored by TUI! 🎉

✨ Every new supporter = another entry for APS Support UK
✨ It’s completely FREE to join
✨ Once you’re signed up, you can raise free donations for us simply by shopping online

So, if you’ve been meaning to join easyfundraising, now is the perfect time!

👉 Sign up here: https://join.easyfundraising.org.uk/aps-support-uk/x011qc/s2s/E7OVWoL0/PMC01/facebook/

💙 Already signed up? Please share this post! The more new supporters who join before Sunday, the more chances we have to win that £5,000.

Thank you for helping us make every shop count! 🛍️💙

19/08/2026

New research highlighted by the Pembrokeshire Herald has drawn attention to the long waits some people in Wales face before receiving a diagnosis for autoimmune and rheumatological conditions.

The Welsh sample reportedly waited 𝗮𝗿𝗼𝘂𝗻𝗱 𝟭𝟭 𝘆𝗲𝗮𝗿𝘀 𝗼𝗻 𝗮𝘃𝗲𝗿𝗮𝗴𝗲 𝗳𝗿𝗼𝗺 𝗳𝗶𝗿𝘀𝘁 𝘀𝘆𝗺𝗽𝘁𝗼𝗺𝘀 𝘁𝗼 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝗶𝘀, with researchers also highlighting barriers including access to specialist services and diagnostic testing.

While APS is not specifically discussed in the article, the findings underline the wider importance of earlier recognition, timely diagnosis and access to specialist care for people living with autoimmune conditions.

Read the article here: https://pembrokeshire-herald.com/136625/patients-in-wales-waiting-years-for-autoimmune-diagnosis/

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Monday	9am - 5pm
Tuesday	9am - 5pm
Wednesday	9am - 5pm
Thursday	9am - 5pm
Friday	9am - 5pm

Website

http://www.aps-support.org.uk/

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