26/08/2026
Accelerating drug discovery with new real-time cell imaging method ๐ฌ๐ก
The Vendrell lab has developed a new method that allows for fluorescent probes to light up when bound to targets of interest on the cell surface. They found the drug avasimibe affects immune cell behaviour important in cancer, multiple sclerosis and rheumatoid arthritis.
Summary ๐: https://edin.ac/4hJIZsz
Full paper ๐๏ธ: https://www.nature.com/articles/s41557-026-02228-0
Image: Microscopy images showing lead fluorogenic peptide (red) binds to PD-1 cell-surface receptor on T-cells when activated (right), but not when T cells are inactive (left).