Inflammatory Bowel Disease and Its Possible Geographical Influences

Inflammatory Bowel Disease and Its Possible Geographical Influences Are you living with in the UK? Does where you live influence Crohn's and Colitis? As researcher

As researchers from Lancaster University and gastroenterologists from Guy's & St Thomas' Hospital, we have launched a very large study of how Crohn's disease spreads across the UK. We aim to see if where patients live has any bearing on whether they get Crohn's disease, ulcerative colitis, microscopic colitis, or indeterminate IBD. Our team includes Professor Jeremy Sanderson and Dr. Gaurav Agrawa

l from Guy's and St Thomas' Hospital in London and Professor Roger Pickup, Professor Peter Atkinson, and Dr. Manoj Roy from Lancaster University with Dr. Glenn Rhodes from the UK Center for Ecology and Hydrology. We aim to obtain data on why this disease occurs to produce a simple survey and more than 3,000 people participated in so far. We therefore would really appreciate it if you could help publicise it.

Our second study, published in BMC Public Health, examined whether is associated with environmental characteristics of...
17/06/2026

Our second study, published in BMC Public Health, examined whether is associated with environmental characteristics of UK river catchments. We found a significant association between Crohn’s disease and pasture land, but not , suggesting a potential disease-specific environmental signal. This provides novel UK-wide evidence of a possible environmental exposure pathway that warrants further investigation.



Background Mycobacterium avium subspecies paratuberculosis (MAP) is the bacterial pathogen which causes Johne’s disease (JD) in animals and is reported to be significantly associated with Crohn’s disease (CD) in humans. MAP is the causative bacterial pathogen of Johne’s disease in infected ani...

Our first study, published in PLOS ONE, used data from over 5,400 participants to map (IBD) across the . The study re...
17/06/2026

Our first study, published in PLOS ONE, used data from over 5,400 participants to map (IBD) across the . The study revealed clear geographical patterns and regional differences in and providing a detailed nationwide overview of IBD distribution in the UK.

Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the gastrointestinal (GI) tract, with two main forms: Crohn’s disease (CD) and ulcerative colitis (UC). While CD can affect any part of the digestive system, UC predominately affects the colon and re**um. The incidence an...

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