HAIR LABS

HAIR LABS Hair Labs is a London research and formulary house studying the biology of hair ageing: greying, shedding, signalling, structure, and restoration.

A grey hair is still a healthy hair. It just lost its colour.That's the part most supplements miss. The cell that grows ...
02/06/2026

A grey hair is still a healthy hair. It just lost its colour.

That's the part most supplements miss. The cell that grows your hair and the cell that colours it are two different cells. Feed the follicle all you like — biotin, keratin, the usual — and the hair still grows. But colour comes from a separate cell, the melanocyte, which is kept topped up by a small reserve of stem cells in the follicle. When that reserve stops being maintained, new hair comes in without pigment. That's greying.

So greying isn't really a hair-growth problem. It's a pigment-cell problem.

The pigment cell still lives inside the follicle, so follicle health matters and we support the whole system — but Anti Grey 1.0 is built around the cell colour actually depends on, not just the one most products feed.

Reference: Nishimura EK, Pigment Cell & Melanoma Research, 2011.

The colour in the hair you see today was decided months ago.Pigment is laid down deep in the follicle, while the hair is...
02/06/2026

The colour in the hair you see today was decided months ago.

Pigment is laid down deep in the follicle, while the hair is still forming. By the time a strand reaches the surface, its colour is set — nothing you put on it, and nothing you do today, changes that particular strand.

So the only honest lever is what the follicle does next. And follicles keep their own clock: months, not mornings. It's why we look at Day 90, not Day 9 — a fair window for biology that simply doesn't hurry.

Anti Grey 1.0 is built for that timescale. If a hair product promises to change your colour by the weekend, it's promising something the follicle can't deliver. We'd rather tell you the truth and earn the ninety days.

Salt and pepper suits you. So does pepper.We're not in the business of telling anyone their hair is a problem. Going gre...
01/06/2026

Salt and pepper suits you. So does pepper.

We're not in the business of telling anyone their hair is a problem. Going grey is a choice. Keeping your colour is a choice. Both are yours.

Hair Labs is the research-led option for one of them — keeping the colour you've still got, for longer. No new grey. We don't promise to undo what's already changed; we work on what's next.

However you wear yours, we think it suits you.

Researched in Kensington. Now launching in the USA.

Every hair is built by two kinds of stem cell.Most people picture a hair as one thing growing out of the scalp. It's act...
30/05/2026

Every hair is built by two kinds of stem cell.

Most people picture a hair as one thing growing out of the scalp. It's actually the output of two separate stem cell populations living side by side at the base of the follicle.

The hair follicle stem cells (an epithelial, keratinocyte lineage) build the structure — the fibre itself. The melanocyte stem cells (descended from the neural crest) make the colour. Different cells, different origins, same niche. And they're coupled: at the start of each new growth phase, both are activated together by WNT signalling, so the strand and its pigment are produced in step rather than by chance.

When you see a hair, you're seeing a collaboration — two cell types, one signal, cycle after cycle.

Rabbani et al., Cell, 2011.

hairlabs.ai

CASE STUDY · Avril, London — sixteen weeks on Anti Grey 1.0 from Hair Labs.Avril's observation at four months: no new gr...
30/05/2026

CASE STUDY · Avril, London — sixteen weeks on Anti Grey 1.0 from Hair Labs.

Avril's observation at four months: no new greys, and hair that feels softer and healthier.

Most products treat greying as one problem with one fix. We don't. Anti Grey 1.0 is formulated against six distinct drivers — signalling, stress, substrate, methylation, structure and oxidation — because what tips one person into greying isn't always what tips the next. The compounds are modelled pairwise across those drivers, in a single daily protocol.

"Four months in, a big change — and I haven't got any new greys. My hair feels so much softer and healthier." — Avril, London

hairlabs.ai

Driver three of six: substrate.Hair colour is manufactured. Pigment is built from a single amino acid — Tyrosine — by on...
30/05/2026

Driver three of six: substrate.

Hair colour is manufactured. Pigment is built from a single amino acid — Tyrosine — by one rate-limiting enzyme called tyrosinase. And tyrosinase itself can't work without Copper held at its active site (Olivares & Solano, Pigment Cell & Melanoma Research, 2009).

That reframes greying. It isn't only a clock running down — it's also a supply chain. Run the production line short on raw material and pigment output drops, even when the cell-recruitment signal and the stress axis are intact.

This is one of six drivers we model: Signalling, Stress, Substrate, Methylation, Structure, Oxidation. Substrate accounts for some greying, not all — which is exactly why we don't treat grey as one thing with one fix.

More at hairlabs.ai.

Greying is not one failure. It is six.Recent research describes a cascade of six interconnected biological drivers at th...
29/05/2026

Greying is not one failure. It is six.

Recent research describes a cascade of six interconnected biological drivers at the hair follicle: signalling failure in the melanocyte stem cell niche, chronic stress-hormone load, substrate and co-factor insufficiency, impaired methylation and metabolic support, structural integrity in the keratin lane, and oxidative pressure as catalase activity declines.

Each driver compounds the others. The shared outcome — the pigment cell stops arriving at the follicle — is the same. The biology behind it is not.

Single-pathway treatments have struggled because the problem is not single-pathway. A serious response begins by naming all six.

Open the Journal — hairlabs.ai/pages/journal

Adrian Lopresti and Stephen Smith reviewed forty-one human trials on Withania somnifera (Journal of Herbal Medicine, 202...
29/05/2026

Adrian Lopresti and Stephen Smith reviewed forty-one human trials on Withania somnifera (Journal of Herbal Medicine, 2021). Across stress, sleep, athletic performance, fertility, cognition, pain, fatigue, and more, the strongest evidence in the literature was for the alleviation of stress and anxiety symptoms.

Why this matters for hair greying. In 2021, Ayelet Rosenberg and colleagues at Columbia (eLife) mapped pigmentation along single hair shafts and found something unexpected: some strands recorded a dark → grey → dark sequence, aligned with periods of stress and recovery. Greying is not a one-way road for every follicle. Where the stem cells are still present and the combined ageing-and-stress load sits close to threshold, pigment can return.

Ashwagandha sits on Driver 02 of the Hair Labs greying map: chronic stress-hormone load — the slower arm of the stress lane.

Open the Journal — hairlabs.ai/pages/journal

Pigment cells don't disappear when hair turns grey. They remain in the follicle bulge — but the signal that recruits the...
28/05/2026

Pigment cells don't disappear when hair turns grey. They remain in the follicle bulge — but the signal that recruits them from that niche weakens.

Keratinocytes secrete Endothelin-1 to call melanocyte stem cells into position. When that signalling pathway fails, the cells stay, but the colour stops arriving.

This is the intervention window — the period before the cell reserve is exhausted. Hair Labs has written Anti Grey 1.0 against this mechanism and five others. The six-driver model, the pairwise apparatus, and the full literature are published on the Research page.

hairlabs.ai/pages/how-it-works

Grey hair is a problem of systems biology. Six interconnected failures at the follicle — signalling, stress load, substr...
27/05/2026

Grey hair is a problem of systems biology. Six interconnected failures at the follicle — signalling, stress load, substrate supply, methylation, fibre structure, and oxidative pressure — and the literature does not converge on a single cause.

To solve a systems problem, you have to systematise the system. Papers on melanocyte stem-cell biology, methylation chemistry, trichology, and follicular redox science were read against the six drivers — not against ingredient categories. More than six hundred candidates were scored on the mechanism they act on. The papers shown here — Nishimura 2005, Zhang 2020, Sun 2023, Iida 2024, Rosenberg 2021, Wood 2009 among them — sit at the centre of that map.

Open the Journal — hairlabs.ai/pages/journal

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