14/08/2026
Before the redness. Before the peeling. Before the pain.
What happens when the first signs of Hand-Foot Syndrome are sensations rather than visible skin changes?
Tingling, burning or increased sensitivity may be easy to dismiss. But during cancer treatment, recognising these changes early can be an important part of supportive care.
As HFS progresses, its impact can extend beyond the skin—affecting mobility, hand function and everyday activities.
The goal isn't to wait for symptoms to become severe. It's to recognise the change early and respond appropriately.
Recognise early. Act early. Support better.
References:
Sferrazza D, et al. Support Care Cancer. 2026;34(6):580. Lacouture ME, et al. Ann Oncol. 2021;32(2):157–170. Piquero-Casals J, et al. Dermatol Ther (Heidelb). 2021;11(6):1905–1915.
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