26/03/2026
Sagger or sinker?
I am a sinker..we all age and it either sags or sinks but don’t worry there’s plenty of options.
As promised a simple comparison of treatments
(Profhilo structura, Profhilo, sculptura (aka plla)
PLLA (Poly-L-Lactic Acid / Sculptra)
What it is: A bio-stimulator, not a “filler” in the traditional sense. It works by stimulating the body’s own collagen production over several months.
Best for: Patients with significant loss of volume (facial volume depletion), deep wrinkles, or sagging skin wanting a long-term, structural improvement rather than immediate filler.
Results: Visible improvements are gradual but long-lasting, often lasting over 2 years.
Target Areas: Cheeks, temples, and jawline
Polynucleotides (PN)
What it is: Regenerative “salmon DNA” injectables that act as messengers to repair cells, increase elastin/collagen, and reduce inflammation.
Best for: Treating complex or damaged skin, including dark circles (under-eyes), crepey skin on the neck, acne scarring, and rosacea.
Results: A “heal and repair” approach, with results developing gradually over 3-4 sessions.
Target Areas: Under-eyes (eye area specialist), neck, and fine acne scars.
Profhilo
What it is: A “bio-remodelling” product made from ultra-pure hyaluronic acid (HA). It does not add volume, but spreads like honey under the skin to hydrate and firm.
Best for: Patients needing intense hydration, a “glow,” and a lifting effect on skin laxity (sagging).
Results: Fast improvements in skin quality, usually requiring 2 sessions, with results lasting around 6 months.
Target Areas: Face, neck, and décolletage
Profhilo Structura
What it is: The new evolution of Profhilo. It is designed to target the subcutaneous superficial fat layers, rather than just the dermis, to provide, lift, and sculpt, rather than just hydrate.
Best for: Mild sagging or loss of contour in the mid-face/jawline, aiming for a “supported” rather than filled look.
Results: Provides a subtle, natural lift and structural reinforcement, with results appearing within 1-2 months.
Target Areas: Mid-face lift, jawline contouring
