21/04/2026
Trigger warning: briefly mentions su***de ideation and self-harming
Random but vitally important public service announcement:
I have just been doing some research for something I am writing, and found various scientific articles pertaining to an issue that not everyone will be aware of - although I am very aware of it, as I suffered from it myself.
Question one: are you aware of a condition called PMDD? [Pre-menstrual dysphoric disorder]
It is a serious form of cyclical depression, related to a woman's menstrual cycle. It is like PMS [pre-menstrual syndrome] 'on steroids', and has an incredibly debilitating affect on a woman's ability to function normally in her day-to-day life for that time in her cycle when estrogen is lowest, and can lead to severe mental health problems, su***de ideation, and self-harming.
Question two: do you have a female friend or family member or partner, who is medically diagnosed ADHD ?
Question three: did you know that the percentage of women assigned female at birth who have been diagnosed with ADHD, who ALSO have PMDD, is 45% - nearly one in two. (source: doi: 10.1007/s00737-011-0232-4 )
For perspective: the incidence of PMDD in American women was between 3-8% according to a study taken in 2003. (source: doi: 10.1016/s0306-4530(03)00098-2 )
Quite the difference, yes? from less than 8/100 to nearly 1/2
So: your ADHD female friend/partner/relative is statistically at risk from suffering a severe form of cyclical depression, related to her menstrual hormones. Look out for symptoms of worsening depression, especially if she is using a form of contraceptive that does not contain estrogen, as estrogen is protective of both dopamine and serotonin levels. This is why the condition worsens during the menstrual cycle when those levels are no longer protected.
And: If you are a female, suffering from a severe form of depression that seems to get dramatically worse during your cycle, talk to your doctor about PMDD.
Feel free to share xx