Dr.Solomon K John

Dr.Solomon K John Senior consultant in Hepato-Pancreato-Biliary, Gastro-Intestinal,Multi-Organ Transplant & keyhole s

Online consultation can be done on prior email or sms or WhatsApp appointments- Call or WhatsApp on 9526410055, if from abroad call or WhatsApp 00919526410055. Email: [email protected], Twitter: Solomon John@solomon40898089 ; Instagram Solomon 'Sunil' John
Hospital Appointments: Welcare Hospital, EMC Kochi, Apollo Adlux Hospital, Kochi & Lakeshore Hospital on Request. Comprehensive care of w

ide range of complex gastro and liver related disease, providing surgical and medical care of high standards.

https://khaleejtimesonline.com/en/nmc-royal-hospital-sharjah-diagnoses-hidden-surgical-condition-behind-severe-vomiting-...
12/04/2026

https://khaleejtimesonline.com/en/nmc-royal-hospital-sharjah-diagnoses-hidden-surgical-condition-behind-severe-vomiting-after-semaglutide/

scheduled follow-up.
Commenting on the case, Dr Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, said:“This case is a timely reminder that not every gastrointestinal symptom in patients taking GLP-1 receptor agonists should be assumed to be a routine medication side effect. When vomiting, weight loss, or upper gastrointestinal symptoms are severe or persistent, clinicians should investigate further to rule out an underlying structural problem. In this case, thorough evaluation and timely surgery allowed us to identify the true cause, avoid unnecessary radical resection, and provide the patient with the right treatment.”
This rare case also reflects an increasingly relevant issue in modern clinical practice. As GLP-1 receptor agonists such as semaglutide become more widely used in the management of both diabetes and obesity, physicians may encounter situations where these medications appear to intensify previously silent gastrointestinal conditions. Because GLP-1 therapies naturally delay gastric emptying, they may worsen symptoms in patients with an undiagnosed fixed anatomical obstruction, bringing an underlying disorder to clinical attention.
Doctors say the broader lesson is clear: persistent vomiting, severe digestive symptoms, or unexplained weight loss in patients taking these medications should not automatically be dismissed as expected side effects without proper investigation. Early diagnosis can uncover hidden disease, prevent malnutrition and complications, and ensure patients receive the most appropriate treatment at the right time.
The successful management of this case at NMC Royal Hospital Sharjah highlights the importance of a multidisciplinary approach, involving surgeons, gastroenterologists, radiologists and endocrinologists in evaluating complex presentations and guiding safe, individualized treatment decisions.

https://menafn.com/arabic/1110914503/%D9%85%D8%B3%D8%AA%D8%B4%D9%81%D9%89-%D8%A5%D9%86-%D8%A5%D9%85-%D8%B3%D9%8A-%D8%B1%...
03/04/2026

https://menafn.com/arabic/1110914503/%D9%85%D8%B3%D8%AA%D8%B4%D9%81%D9%89-%D8%A5%D9%86-%D8%A5%D9%85-%D8%B3%D9%8A-%D8%B1%D9%88%D9%8A%D8%A7%D9%84-%D8%A7%D9%84%D8%B4%D8%A7%D8%B1%D9%82%D8%A9-%D9%8A%D9%86%D8%AC%D8%AD-%D9%81%D9%8A-%D8%AA%D8%B4%D8%AE%D9%8A%D8%B5-%D8%AD%D8%A7%D9%84%D8%A9-%D9%86%D8%A7%D8%AF%D8%B1%D8%A9-%D9%88%D8%A5%D9%86%D9%87%D8%A7%D8%A1-%D9%85%D8%B9%D8%A7%D9%86%D8%A7%D8%A9-%D9%85%D8%B1%D9%8A%D8%B6-%D9%85%D9%86-%D8%A3%D8%B9%D8%B1%D8%A7%D8%B6-%D9%87%D8%B6%D9%85%D9%8A%D8%A9-%D8%B4%D8%AF%D9%8A%D8%AF%D8%A9

Sharjah: A medical team at NMC Royal Hospital Sharjah successfully diagnosed a rare congenital condition in a 55-year-old patient after he suffered for a long time from severe digestive symptoms and significant weight loss. This case underscores the importance of further medical investigations when symptoms persist or worsen, rather than simply assuming they are expected side effects of certain medications.
The patient, who suffers from type 2 diabetes, visited the hospital due to increasing digestive symptoms that became more pronounced after using semaglutide, a newer medication used to control blood sugar levels and aid weight loss. Although this type of treatment can be associated with some known digestive disturbances, the severity and persistence of the symptoms necessitated a comprehensive diagnostic evaluation to search for an underlying cause.
The test results revealed that the patient had a partial annular pancreas, a rare congenital condition in which pancreatic tissue partially surrounds the duodenum, causing narrowing of the second part of the pancreas and obstruction of the gastric outlet, thus preventing the normal passage of food. Tests also revealed the presence of gallstones accompanied by symptoms.
The diagnostic process included a range of advanced tests, such as CT scans, MRI, endoscopic ultrasound, duodenal biopsy, and repeated tumor marker tests, to rule out any suspicion of malignancy, especially given the weight loss and the nature of the symptoms. All results confirmed the absence of any evidence of cancer.
Dr. Solomon John, a consultant surgeon at NMC Royal Hospital Sharjah, oversaw the case. Surgical intervention was deemed necessary due to the persistence of symptoms and their direct impact on the patient's health and quality of life.
During the procedure, a dilation of the first part of the duodenum was observed, followed by a marked narrowing of the second part, which was surrounded by pancreatic tissue, consistent with a diagnosis of annular pancreas. To ensure the selection of the most appropriate surgical approach, an intraoperative frozen biopsy was performed, which confirmed the tissue's benign nature, allowing the medical team to avoid unnecessary major surgery.
Accordingly, the team performed a Roux-en-Y gastrostomy with a jejunostomy to bypass the obstruction, along with a cholecystectomy due to symptomatic gallstones. Subsequent histological examination confirmed the presence of benign pancreatic tissue with chronic fibrosis.
The patient's condition improved well post-operatively, with a stable and uncomplicated recovery period. He gradually regained his ability to eat before being discharged from the hospital with a follow-up medical program.
Dr. Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, said:
“This case highlights the importance of not hastily interpreting severe or persistent gastrointestinal symptoms as solely medication side effects, especially when the symptoms are unusual in their severity or duration. A thorough assessment and appropriate surgical intervention helped us identify the true cause of the condition, provide suitable treatment, and avoid unnecessary radical surgery.”
This case highlights the importance of paying close attention to persistent gastrointestinal symptoms in patients using GLP-1 receptor agonists such as semaglutide, especially given their increasing use in treating diabetes and obesity. These medications slow gastric emptying, which can sometimes reveal underlying organic problems or exacerbate existing symptoms in patients with undiagnosed gastrointestinal strictures or obstructions.
The case also underscores the importance of a multidisciplinary approach, involving collaboration between surgical, gastroenterological, radiological, and endocrinological teams, to achieve accurate diagnosis and develop the most appropriate treatment plan for each individual case.

https://mid-east.info/nmc-royal-hospital-sharjah-diagnoses-hidden-surgical-condition-behind-severe-vomiting-after-semagl...
03/04/2026

https://mid-east.info/nmc-royal-hospital-sharjah-diagnoses-hidden-surgical-condition-behind-severe-vomiting-after-semaglutide/

Sharjah: Doctors at NMC Royal Hospital Sharjah have successfully diagnosed and treated a rare congenital surgical condition in a 55-year-old man whose severe vomiting and rapid weight loss worsened after starting semaglutide, highlighting an important message for both clinicians and patients in the era of widely used diabetes and weight-management medications. Hospitals & Treatment Centers

The patient, who had type 2 diabetes mellitus and was already on metformin, began experiencing progressive vomiting after meals over several months, along with significant unintentional weight loss. His symptoms became markedly worse shortly after the introduction of semaglutide, a GLP-1 receptor agonist commonly prescribed to improve blood sugar control and support weight reduction.

Because nausea, appetite suppression and weight loss are known side effects of semaglutide and similar medications, the patient’s condition could easily have been attributed to the drug alone. However, the severity and persistence of his symptoms prompted doctors at NMC Royal Hospital Sharjah to investigate further for an underlying structural cause. Travel Guides & Travelogues

Detailed imaging and diagnostic evaluation revealed that the patient had a partial annular pancreas, a rare congenital abnormality in which pancreatic tissue partially surrounds the duodenum. In this case, the condition had caused narrowing in the second part of the duodenum, resulting in gastric outlet obstruction and preventing food from passing normally from the stomach into the small intestine. He was also found to have symptomatic cholelithiasis, or gallstones.

Given the overlap between expected medication side effects and the patient’s worsening gastrointestinal symptoms, the case presented a significant diagnostic challenge. The medical team carried out extensive investigations, including CT scan, MRI, endoscopic ultrasound, duodenal biopsy, and repeated tumour marker testing, to rule out malignancy. These tests showed no evidence of cancer, despite initial concern due to the nature of the obstruction and the patient’s weight loss.

The case was managed by Dr Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, who led the surgical team in planning a definitive intervention after the patient’s symptoms remained debilitating. Medical Facilities & Services

During surgery, doctors found a dilated first part of the duodenum transitioning to a narrowed second segment encircled by pancreatic tissue, confirming the diagnosis of annular pancreas. Importantly, no visible mass or metastatic deposits were identified. To avoid unnecessary radical surgery, the team performed an intraoperative frozen section biopsy, which confirmed that the tissue was benign.

With cancer excluded, the surgeons were able to avoid a pancreaticoduodenectomy (Whipple procedure) and instead proceed with a more appropriate and organ-preserving treatment. The patient underwent a Roux-en-Y gastrojejunostomy with jejunojejunostomy to bypass the obstruction, along with cholecystectomy to remove the gallbladder. Final pathology later confirmed benign pancreatic tissue with chronic fibrosis.

The patient’s postoperative recovery was uncomplicated. He gradually resumed oral intake, tolerated his diet well, and was discharged with scheduled follow-up.

Commenting on the case, Dr Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, said:
“This case is a timely reminder that not every gastrointestinal symptom in patients taking GLP-1 receptor agonists should be assumed to be a routine medication side effect. When vomiting, weight loss, or upper gastrointestinal symptoms are severe or persistent, clinicians should investigate further to rule out an underlying structural problem. In this case, thorough evaluation and timely surgery allowed us to identify the true cause, avoid unnecessary radical resection, and provide the patient with the right treatment.”

This rare case also reflects an increasingly relevant issue in modern clinical practice. As GLP-1 receptor agonists such as semaglutide become more widely used in the management of both diabetes and obesity, physicians may encounter situations where these medications appear to intensify previously silent gastrointestinal conditions. Because GLP-1 therapies naturally delay gastric emptying, they may worsen symptoms in patients with an undiagnosed fixed anatomical obstruction, bringing an underlying disorder to clinical attention. Hospitals & Treatment Centers

Doctors say the broader lesson is clear: persistent vomiting, severe digestive symptoms, or unexplained weight loss in patients taking these medications should not automatically be dismissed as expected side effects without proper investigation. Early diagnosis can uncover hidden disease, prevent malnutrition and complications, and ensure patients receive the most appropriate treatment at the right time. Travel Guides & Travelogues

The successful management of this case at NMC Royal Hospital Sharjah highlights the importance of a multidisciplinary approach, involving surgeons, gastroenterologists, radiologists and endocrinologists in evaluating complex presentations and guiding safe, individualized treatment decisions.

https://thegulfnow.com/nmc-royal-hospital-sharjah-diagnoses-hidden-surgical-condition-behind-severe-vomiting-after-semag...
03/04/2026

https://thegulfnow.com/nmc-royal-hospital-sharjah-diagnoses-hidden-surgical-condition-behind-severe-vomiting-after-semaglutide/

Sharjah: Doctors at NMC Royal Hospital Sharjah have successfully diagnosed and treated a rare congenital surgical condition in a 55-year-old man whose severe vomiting and rapid weight loss worsened after starting semaglutide, highlighting an important message for both clinicians and patients in the era of widely used diabetes and weight-management medications.

The patient, who had type 2 diabetes mellitus and was already on metformin, began experiencing progressive vomiting after meals over several months, along with significant unintentional weight loss. His symptoms became markedly worse shortly after the introduction of semaglutide, a GLP-1 receptor agonist commonly prescribed to improve blood sugar control and support weight reduction.

Because nausea, appetite suppression and weight loss are known side effects of semaglutide and similar medications, the patient’s condition could easily have been attributed to the drug alone. However, the severity and persistence of his symptoms prompted doctors at NMC Royal Hospital Sharjah to investigate further for an underlying structural cause.

Detailed imaging and diagnostic evaluation revealed that the patient had a partial annular pancreas, a rare congenital abnormality in which pancreatic tissue partially surrounds the duodenum. In this case, the condition had caused narrowing in the second part of the duodenum, resulting in gastric outlet obstruction and preventing food from passing normally from the stomach into the small intestine. He was also found to have symptomatic cholelithiasis, or gallstones.

Given the overlap between expected medication side effects and the patient’s worsening gastrointestinal symptoms, the case presented a significant diagnostic challenge. The medical team carried out extensive investigations, including CT scan, MRI, endoscopic ultrasound, duodenal biopsy, and repeated tumour marker testing, to rule out malignancy. These tests showed no evidence of cancer, despite initial concern due to the nature of the obstruction and the patient’s weight loss.

The case was managed by Dr Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, who led the surgical team in planning a definitive intervention after the patient’s symptoms remained debilitating.

During surgery, doctors found a dilated first part of the duodenum transitioning to a narrowed second segment encircled by pancreatic tissue, confirming the diagnosis of annular pancreas. Importantly, no visible mass or metastatic deposits were identified. To avoid unnecessary radical surgery, the team performed an intraoperative frozen section biopsy, which confirmed that the tissue was benign.

With cancer excluded, the surgeons were able to avoid a pancreaticoduodenectomy (Whipple procedure) and instead proceed with a more appropriate and organ-preserving treatment. The patient underwent a Roux-en-Y gastrojejunostomy with jejunojejunostomy to bypass the obstruction, along with cholecystectomy to remove the gallbladder. Final pathology later confirmed benign pancreatic tissue with chronic fibrosis.

The patient’s postoperative recovery was uncomplicated. He gradually resumed oral intake, tolerated his diet well, and was discharged with scheduled follow-up.

Commenting on the case, Dr Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, said:
“This case is a timely reminder that not every gastrointestinal symptom in patients taking GLP-1 receptor agonists should be assumed to be a routine medication side effect. When vomiting, weight loss, or upper gastrointestinal symptoms are severe or persistent, clinicians should investigate further to rule out an underlying structural problem. In this case, thorough evaluation and timely surgery allowed us to identify the true cause, avoid unnecessary radical resection, and provide the patient with the right treatment.”

This rare case also reflects an increasingly relevant issue in modern clinical practice. As GLP-1 receptor agonists such as semaglutide become more widely used in the management of both diabetes and obesity, physicians may encounter situations where these medications appear to intensify previously silent gastrointestinal conditions. Because GLP-1 therapies naturally delay gastric emptying, they may worsen symptoms in patients with an undiagnosed fixed anatomical obstruction, bringing an underlying disorder to clinical attention.

Doctors say the broader lesson is clear: persistent vomiting, severe digestive symptoms, or unexplained weight loss in patients taking these medications should not automatically be dismissed as expected side effects without proper investigation. Early diagnosis can uncover hidden disease, prevent malnutrition and complications, and ensure patients receive the most appropriate treatment at the right time.

The successful management of this case at NMC Royal Hospital Sharjah highlights the importance of a multidisciplinary approach, involving surgeons, gastroenterologists, radiologists and endocrinologists in evaluating complex presentations and guiding safe, individualized treatment decisions.

NMC Royal Hospital Sharjah diagnoses hidden surgical condition behind severe vomiting after semaglutide.https://ksajourn...
03/04/2026

NMC Royal Hospital Sharjah diagnoses hidden surgical condition behind severe vomiting after semaglutide.

https://ksajournal.com/nmc-royal-hospital-sharjah-diagnoses-hidden-surgical-condition-behind-severe-vomiting-after-semaglutide/

Sharjah: Doctors at NMC Royal Hospital Sharjah have successfully diagnosed and treated a rare congenital surgical condition in a 55-year-old man whose severe vomiting and rapid weight loss worsened after starting semaglutide, highlighting an important message for both clinicians and patients in the era of widely used diabetes and weight-management medications.

The patient, who had type 2 diabetes mellitus and was already on metformin, began experiencing progressive vomiting after meals over several months, along with significant unintentional weight loss. His symptoms became markedly worse shortly after the introduction of semaglutide, a GLP-1 receptor agonist commonly prescribed to improve blood sugar control and support weight reduction.

Because nausea, appetite suppression and weight loss are known side effects of semaglutide and similar medications, the patient’s condition could easily have been attributed to the drug alone. However, the severity and persistence of his symptoms prompted doctors at NMC Royal Hospital Sharjah to investigate further for an underlying structural cause.

Detailed imaging and diagnostic evaluation revealed that the patient had a partial annular pancreas, a rare congenital abnormality in which pancreatic tissue partially surrounds the duodenum. In this case, the condition had caused narrowing in the second part of the duodenum, resulting in gastric outlet obstruction and preventing food from passing normally from the stomach into the small intestine. He was also found to have symptomatic cholelithiasis, or gallstones.

Given the overlap between expected medication side effects and the patient’s worsening gastrointestinal symptoms, the case presented a significant diagnostic challenge. The medical team carried out extensive investigations, including CT scan, MRI, endoscopic ultrasound, duodenal biopsy, and repeated tumour marker testing, to rule out malignancy. These tests showed no evidence of cancer, despite initial concern due to the nature of the obstruction and the patient’s weight loss.

The case was managed by Dr Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, who led the surgical team in planning a definitive intervention after the patient’s symptoms remained debilitating.

During surgery, doctors found a dilated first part of the duodenum transitioning to a narrowed second segment encircled by pancreatic tissue, confirming the diagnosis of annular pancreas. Importantly, no visible mass or metastatic deposits were identified. To avoid unnecessary radical surgery, the team performed an intraoperative frozen section biopsy, which confirmed that the tissue was benign.

With cancer excluded, the surgeons were able to avoid a pancreaticoduodenectomy (Whipple procedure) and instead proceed with a more appropriate and organ-preserving treatment. The patient underwent a Roux-en-Y gastrojejunostomy with jejunojejunostomy to bypass the obstruction, along with cholecystectomy to remove the gallbladder. Final pathology later confirmed benign pancreatic tissue with chronic fibrosis.

The patient’s postoperative recovery was uncomplicated. He gradually resumed oral intake, tolerated his diet well, and was discharged with scheduled follow-up.

Commenting on the case, Dr Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, said:
“This case is a timely reminder that not every gastrointestinal symptom in patients taking GLP-1 receptor agonists should be assumed to be a routine medication side effect. When vomiting, weight loss, or upper gastrointestinal symptoms are severe or persistent, clinicians should investigate further to rule out an underlying structural problem. In this case, thorough evaluation and timely surgery allowed us to identify the true cause, avoid unnecessary radical resection, and provide the patient with the right treatment.”

This rare case also reflects an increasingly relevant issue in modern clinical practice. As GLP-1 receptor agonists such as semaglutide become more widely used in the management of both diabetes and obesity, physicians may encounter situations where these medications appear to intensify previously silent gastrointestinal conditions. Because GLP-1 therapies naturally delay gastric emptying, they may worsen symptoms in patients with an undiagnosed fixed anatomical obstruction, bringing an underlying disorder to clinical attention.

Doctors say the broader lesson is clear: persistent vomiting, severe digestive symptoms, or unexplained weight loss in patients taking these medications should not automatically be dismissed as expected side effects without proper investigation. Early diagnosis can uncover hidden disease, prevent malnutrition and complications, and ensure patients receive the most appropriate treatment at the right time.

The successful management of this case at NMC Royal Hospital Sharjah highlights the importance of a multidisciplinary approach, involving surgeons, gastroenterologists, radiologists and endocrinologists in evaluating complex presentations and guiding safe, individualized treatment decisions.

https://alwahdanews.ae/articles/%D9%85%D8%B3%D8%AA%D8%B4%D9%81%D9%89-%D8%A7%D9%84%D8%B4%D8%A7%D8%B1%D9%82%D8%A9-%D9%8A%D...
03/04/2026

https://alwahdanews.ae/articles/%D9%85%D8%B3%D8%AA%D8%B4%D9%81%D9%89-%D8%A7%D9%84%D8%B4%D8%A7%D8%B1%D9%82%D8%A9-%D9%8A%D9%86%D8%AC%D8%AD-%D9%81%D9%8A-%D8%AA%D8%B4%D8%AE%D9%8A%D8%B5-%D8%AD%D8%A7%D9%84%D8%A9-%D9%86%D8%A7%D8%AF%D8%B1%D8%A9-%D9%88%D8%A5%D9%86%D9%87%D8%A7%D8%A1-%D9%85%D8%B9%D8%A7%D9%86%D8%A7%D8%A9-%D9%85%D8%B1%D9%8A%D8%B6-%D9%85%D9%86-%D8%A3%D8%B9%D8%B1%D8%A7%D8%B6-%D9%87%D8%B6%D9%85%D9%8A%D8%A9-%D8%B4%D8%AF%D9%8A%D8%AF%D8%A9

A medical team at NMC Royal Hospital Sharjah successfully diagnosed a rare congenital condition in a 55-year-old patient, after a long struggle with severe digestive symptoms and significant weight loss. This incident underscores the importance of expanding medical examinations when symptoms persist or worsen, and not simply considering them as expected side effects of some drug treatments.
The patient, who had type 2 diabetes, presented to the hospital with increasing digestive symptoms that had become more pronounced after using semaglutide, a newer medication used to control blood sugar levels and aid weight loss. Although this type of treatment can be associated with some known digestive disturbances, the severity and persistence of the symptoms warranted a more extensive diagnostic evaluation to investigate an underlying cause.
Test results showed that the patient suffered from partial annular pancreas, a rare congenital condition in which pancreatic tissue partially surrounds the duodenum, causing narrowing of the second part of the duodenum and obstruction of the gastric outlet, thus preventing the normal passage of food. Tests also revealed the presence of symptomatic gallstones.
The diagnostic process included a range of advanced tests, such as CT scans, MRI scans, endoscopic ultrasound, duodenal biopsy, and repeated tumor marker tests, all aimed at ruling out any suspicion of malignancy, especially given the weight loss and the nature of the symptoms. All results confirmed the absence of any evidence of cancer.
The case was treated by Dr. Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, where surgical intervention was decided upon after the symptoms persisted and had a direct impact on the patient’s health and quality of life.
During the procedure, dilation of the first part of the duodenum was observed, followed by marked narrowing of the second part, which was surrounded by pancreatic tissue, consistent with a diagnosis of annular pancreas. To ensure the selection of the most appropriate surgical approach, an intraoperative frozen biopsy was performed, confirming the tissue's benign nature and the absence of malignancy, thus allowing the medical team to avoid unnecessary major surgery.
Accordingly, the team performed a Roux-en-Y gastrostomy with a jejunostomy to bypass the obstruction, along with cholecystectomy due to symptomatic gallstones. Subsequent definitive histological examination confirmed the presence of benign pancreatic tissue with chronic fibrosis.
The patient's condition improved well after the operation, with a stable recovery period without complications, and he was gradually able to regain his ability to eat before being discharged from the hospital with a subsequent medical follow-up program.
Dr. Solomon John, Consultant Surgeon at NMC Royal Hospital Sharjah, said:
"This case highlights the importance of not rushing to interpret severe or persistent digestive symptoms as solely drug side effects, especially when the symptoms are unusual in their severity or duration. A careful assessment and appropriate surgical intervention helped us identify the true cause of the condition, provide suitable treatment, and avoid unnecessary radical surgery."
This case highlights the importance of monitoring persistent gastrointestinal symptoms in patients using GLP-1 receptor agonists such as semaglutide, especially given their increasing use in treating diabetes and obesity. These medications slow gastric emptying, which can sometimes reveal underlying organic problems or exacerbate existing symptoms in patients with undiagnosed gastrointestinal strictures or obstructions.
The case also underscores the importance of a multidisciplinary medical approach, through collaboration between surgical, gastroenterological, radiological and endocrine teams, to reach an accurate diagnosis and develop the most appropriate treatment plan for each case.

20/02/2026

Vitamin D deficiency

Crohn's DiseaseCrohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastroin...
26/01/2026

Crohn's Disease

Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract.[3] Symptoms often include abdominal pain, diarrhea, fever, abdominal distension, and weight loss.[1][3] Complications outside of the gastrointestinal tract may include anemia, skin rashes, arthritis, inflammation of the eye, and fatigue.[1] The skin rashes may be due to infections, as well as pyoderma gangrenosum or erythema nodosum.[1] Bowel obstruction may occur as a complication of chronic inflammation, and those with the disease are at much greater risk of colorectal cancer and small bowel cancer.[1]

Although the precise causes of Crohn's disease (CD) are unknown, it is believed to be caused by a combination of environmental, immune, and bacterial factors in genetically susceptible individuals.[3][13][14][15] It results in a chronic inflammatory disorder, in which the body's immune system defends the gastrointestinal tract, possibly targeting microbial antigens.[14][16] Although Crohn's is an immune-related disease, it does not seem to be an autoimmune disease (the immune system is not triggered by the body itself).[17] The exact underlying immune problem is not clear; however, it may be an immunodeficiency state.[16][18][19]

About half of the overall risk is related to genetics, with more than 70 genes involved.[1][20] To***co smokers are three times as likely to develop Crohn's disease as non-smokers.[6] Crohn's disease is often triggered after a gastroenteritis episode.[1] Other conditions with similar symptoms include irritable bowel syndrome and Behçet's disease.[1]

Read more .... https://en.wikipedia.org/wiki/Crohn%27s_disease

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