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Upsurgeon

Casa
Italia
Assago
Upsurgeon

UpSurgeOn is a cadaver-free simulation-based platform for psychomotor surgical skill enhancement using virtual and physical simulations.

It is currently focused on microsurgeries (neurosurgery, plastic surgery, ENT surgery, maxillofacial surgery, and spine surgery). The team is made up of Neurosurgeons, Residents, Medical Students, Digital Artists, Developers, Bioengineers, Graphic Designers, and Free-thinkers. UpSurgeOn was founded in 2017 by two neurosurgeons, Dr. Federico Nicolosi (Founder and CEO) and Dr. Giannantonio Spena (Co

-founder), and is headquartered in Milan, Italy. UpSurgeOn has been supported by the EIC (European Innovation Council) through the Horizon 2020 program (grant n 880895).

19/06/2026

The lights are turning on.
A new chapter is about to begin.
Be ready for something incredible.

Coming soon.

08/05/2026

🇺🇸 UpSurgeOn at AANS 2026 | Texas, USA

One of the biggest neurosurgery congresses in the world.

UpSurgeOn works across multiple disciplines, but it was born from neurosurgery. And AANS is our natural environment.

💡Surgeons, innovators, and free-thinkers who think outside the box shared with us their vision for the future of surgery: pushing limits, exchanging ideas, and creating new opportunities to achieve excellence.

We are proud to have been part of this incredible edition, connecting with a global community driven by purpose.

🚀 It was amazing to welcome such an incredible flow of visitors to our booth and guide them through our cranial and spine technologies.

A sincere thank you to AANS and to everyone who stopped by, sharing this journey with us.

Thank you to our partners in the US and UK, Inovus.

24/04/2026

🇨🇦 IMAST Annual Meeting 2026 | Toronto, Canada

Incredible moments at the IMAST Annual Meeting 2026 with world-class Surgeons and Researchers sharing data, experiences, and results.

We are proud to have showcased our MOST ADVANCED and COMPLETE TECHNOLOGY inside the Metro Toronto Convention Centre, right at the heart of innovation.

What stood out most is how complex concepts take on a completely new dimension when they can be explored visually and experienced beyond theory.
This is the kind of learning we truly believe in, where understanding becomes tangible and knowledge turns into practice.

🙏🏻 Grateful to contribute to moments that make science more accessible, engaging, and impactful on a global stage.

23/04/2026

🇺🇸 AANS 2026 | Texas, USA

🗓️ May 1–4, 2026
📍 San Antonio, Texas - BOOTH 848

Our advanced technologies are designed by neurosurgeons to enhance skills both on cranial and spine surgery, combining crazy realism and cutting-edge engineering.

Let's meet to discover the next level of surgical training science!

21/04/2026

🚨 UPGRADE YOUR ENDOSCOPIC TRAINING 🚨

🆕 NEW FEATURE:
1.⁠ ⁠REALISTIC INTRADURAL ANATOMY with CSF, taking it to the NEXT-LEVEL.
2. Extra Vertebral tissue is NOW RADIOFREQUENCY-COMPATIBLE.

⭐ In just one year, THOUSANDS of surgeons already choose the Endoscopic LumbarBox, and the number keep growing!

Why?
Because it finally lets you train the way you operate.

✅ 10 operable levels = unlimited procedures
✅ Hyper-realistic anatomy
✅ Cost-effective, always available
✅ App with X-ray

🔥 Special PROMO now, don’t miss it.

🔗 Request a quote here:
https://www.upsurgeon.com/endoscopic-lumbarbox

10/04/2026

🔬 Another Independent Peer-Reviewed Papers Proves That UpSurgeOn Improves Surgical Training! 😉

⭐ A recent study published in World Neurosurgery, tested our advanced technology.
Here’s how Endoscopic LumbarBox performed. 🤩

✨ Key results:

✅ 76.5% – Enhanced surgical performance
✅ 68% – Improved procedural accuracy
✅ 67% - Fewer procedural errors
✅ 40% - Faster task completion
✅ Self-efficacy more than doubled!

«The three-dimensional simulation model demonstrated strong validity and reliability for UBE discectomy training»

📊 Safe. Repeatable. Advanced.
❤️ Because every great surgeon starts with the right practice.

🙏🏻 Big thanks to the authors!
Dr. Oğuz Kağan Demirtaş, Dr. Hayri Kertmen, Dr. Habibullah Dolgun, Dr. İlker Solmaz, Dr. Mehmet İlker Özer, Dr. Bilal Abbasoğlu, Dr. Süleyman Çağrı Akpınar, Dr. Baran Can Alpergin, Dr. Caner Ünlüer, Dr. Çağrı Elbir, Dr. Göktuğ Ülkü.

🔗 Explore more peer-reviewed research: upsurgeon.com/publications
📚 Read the full study: https://www.sciencedirect.com/science/article/pii/S1878875026001026

07/04/2026

🚀 CRESCENDO 2026 – Verona, Italy! 🇮🇹

🔥 WOW! Three days. World-class Masters.
Hands-on learning.
A COMMUNITY of passionate Surgeons.

Innovators changing the way surgical training is built.

⭐ SIMULATION + CADAVERIC DISSECTION + COMMUNITY = a powerful formula that truly works.

📊 Intense, dynamic, and full of moments that remind you why we’re here.

❤️ Thank you to the directors, faculty, and everyone involved for making this experience unforgettable!

23/03/2026

Excellence grows with practice, and the right environment: SIMULATION + CADAVERIC DISSECTION!

🤩 Here’s your chance to experience it firsthand:

CrescEndo, Fifth Edition – Verona, Italy 🇮🇹

📅 28–30 March 2026
📍 ICLO Teaching and Research Center

🔬 Learn from some of the BEST SURGEONS from across ITALY, with inspiring LECTURES and a lot of HANDS-ON training!

🌟 A big thanks to the organizers and faculty for making this outstanding event!

Heading to Verona! 🇮🇹

23/03/2026

WE’VE JUST CLOSED A €5M ROUND. 🎉

We’re about to step into the next level of creative madness! 😎

Get ready.
And most of all… enjoy the ride!

Because in the middle of all this chaos, growth, and ambition, it’s easy to forget why we do it.

We do it for patients, all around the world.

Thanks to our global, passionate community. 🌍
The UpSurgeOn team 🚀

P.S. Why the giant robot?
Because when the right people come together, a superpower emerges — the whole is greater than the sum of its parts.
That’s magic. 🚀

20/03/2026

📣 MAJOR ANNOUNCEMENT 🎉

UpSurgeOn is immensely proud to announce the closing of a €5M funding round. This is a major milestone that will accelerate our global expansion and mark the beginning of an exciting new chapter.

💡 One idea born in the operating room by two neurosurgeons, Dr. Federico Nicolosi and Dr. Giannantonio Spena.
💙 A team that kept growing and innovating.
🚀 The first simulation technology launched in 2021.

Today, that idea has become a company reaching surgeons and medtech companies in over 130 countries, across 5 surgical disciplines, supporting thousands of procedures and training experiences worldwide.

A vision built by surgeons, for surgeons.
Making surgical excellence accessible on a global scale.

What started as a bold intuition is now a growing ecosystem of innovation, built together with an outstanding team, trusted partners, and a global community that believed in this vision from day one.

This milestone marks a turning point. It opens a new chapter that will enable UpSurgeOn to scale across technologies, disciplines, and geographies faster than ever before.

This is just the beginning.

Grateful to our new investors CDP Venture Capital, Deep Ocean Capital, Azimut, FBH for their trust and support.

Incredibly excited for what comes next.
This is dedicated to our entire community and our extraordinary, passionate team.

https://www.upsurgeon.com/upsurgeon-announces-e5-million-investment-round-to-accelerate-global-expansion/

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