28/11/2022
久々の更新になります。今年度よりインド出身のSharmila Ghoshさん(文部科学省国費外国人留学生)が研究室に加わりました。腸管幹細胞を可視化するLgr5-EGFPノックインマウスを用い、回復期腸管の幹細胞数と放射線防護剤の防護活性を裏付ける幹細胞動態を明らかにする研究に取り組んでいます。
以下は、本人のメッセージになります。今後ともどうかよろしくお願い申し上げます。
I am Sharmila Ghosh from India I am a Doctoral student in Professor Morita's Laboratory joined in April 2022.
Our laboratory is working rigorously on finding a way to reduce the side effects of cancer treatment caused by radiation. My aspiration towards working on cancer research started when I was a master’s student. The first time when I was taught the fascinating properties of cancer cells it occurred to me how smart these cells are the way they tackle the treatment and finds their way to come back.
One of the seed compounds, 5CHQ (5-chloro-8-quinolinol) has shown a stronger radioprotective activity, by modulating the p53 activity.
There are still lots of unanswered questions related to 5CHQ like its activity on long survival studies, the gene responsible for the radioprotective effect, and the p53 dependence of the 5CHQ effect.
I want to keep working on finding and explore more on these unanswered areas.
To continue doing so the research funding plays a very crucial role I am thankful to each one who contributed to this funding.
We are up against the smartest cells of all this is where we all need to come together as a society and play our part and win against it. I believe if in any way we can contribute to reducing the suffering of cancer patient's our life will be fruitful.
I have found my IKIGAI through research and will continue doing so