20/05/2026
𝐔𝐧𝐝𝐞𝐫𝐬𝐭𝐚𝐧𝐝𝐢𝐧𝐠 𝐂𝐃 𝐌𝐚𝐫𝐤𝐞𝐫𝐬 𝐢𝐧 𝐇𝐞𝐦𝐚𝐭𝐨𝐥𝐨𝐠𝐲
CD markers play a crucial role in identifying cell lineage and diagnosing hematological malignancies through flow cytometry.
Some commonly used markers:
🔹 CD34+ → Blast cells
🔹 CD3+ → T-cell lineage
🔹 CD19+ → B-cell lineage
🔹 CD33+ → Myeloid lineage
Common Associations:
• CD34+ CD19+ → B-ALL
• CD34+ CD3+ → T-ALL
• CD34+ CD33+ → AML
• CD34− CD33+ → APL
These markers are essential in differentiating acute leukemias and guiding accurate diagnosis and treatment strategies in clinical hematology.
Flow cytometry remains one of the most powerful diagnostic tools in modern laboratory medicine and oncology.