Sante Plus Pharmacie

23/05/2026

Massive clinical trial shows daily multivitamins slow cellular aging.

Researchers from Mass General Brigham have identified a simple, accessible tool in the quest for healthier longevity: the daily multivitamin.

By analyzing data from the large-scale COSMOS clinical trial, scientists found that consistent multivitamin use slowed biological aging by approximately four months over a two-year period. Using advanced "epigenetic clocks" that measure chemical changes in DNA, the team observed significant slowing in cellular decay across multiple biological markers. This effect was most pronounced in individuals who were already aging faster than their chronological years at the start of the study, suggesting the supplement provides a critical boost to those most at risk.

In the United States, approximately one-third of adults already take a multivitamin daily, making this discovery relevant to over 80 million people looking to optimize their health.

While chronological age is a fixed number, biological age reflects the actual health and wear of your cells, often predicting the risk of chronic disease and mortality. Senior author Howard Sesso notes that these findings open new doors for safe, low-cost interventions that help people not just live longer, but live better. The research suggests that the same supplements linked to improved cognition and cancer prevention may also be fundamentally slowing the body’s internal clock. As scientists continue to track these participants, the results offer a compelling reason to reconsider the humble multivitamin as a cornerstone of proactive aging and long-term health maintenance.

source: Mass General Brigham. (2026). Daily Multivitamins May Slow Aging. Nature Medicine.

14/04/2026

27/03/2026

🗞️ [À lire dans Le Défi Quotidien] Produits pharmaceutiques hors officine : Quand la loi dit tout et son contraire

Certains produits pharmaceutiques sont en vente libre dans les supermarchés et les boutiques de quartier. C’est une pratique qui soulève des questions sur le respect de la Pharmacy Act, la concurrence déloyale et la sécurité des consommateurs. Retrouvez l’intégralité de cet article dans Le Défi Quotidien de ce vendredi 27 mars 2026.

11/02/2026

02/02/2026

Chronic metformin treatment is associated with Vitamin B₁₂ (cobalamin) deficiency.

Why?
Metformin reduces the absorption of vitamin B₁₂ in the intestine, especially with long-term use.

Possible effects of B₁₂ deficiency:
• Anemia (megaloblastic anemia)
• Peripheral neuropathy (numbness, tingling in hands/feet)
• Fatigue and weakness

Chronic use of metformin, a commonly prescribed medication for type 2 diabetes, has been associated with Vitamin B₁₂ (cobalamin) deficiency. This deficiency occurs due to several factors, including:

1. Malabsorption: Metformin may affect the intestinal absorption of Vitamin B₁₂ by altering the gut microbiome and affecting small intestine motility.

2. Inhibition of Vitamin B₁₂ Transfer: The medication can inhibit the activity of certain factors that are responsible for transporting Vitamin B₁₂ across the intestinal wall into the bloodstream.

3. Increased Gut Bacteria: The alteration in the gut flora can lead to bacterial overgrowth, which can consume Vitamin B₁₂ before it is absorbed.

Treatment Options for Vitamin B₁₂ Deficiency

1. Vitamin B₁₂ Supplements: Oral or intramuscular injections can effectively replenish Vitamin B₁₂ levels in those with a deficiency.

2. Dietary Sources: Increasing intake of Vitamin B₁₂-rich foods can help manage and prevent deficiency:
- Animal Products: Meat, fish, eggs, and dairy products are the primary sources of Vitamin B₁₂.
- Fortified Foods: Some plant-based milk, breakfast cereals, and nutritional yeasts are fortified with Vitamin B₁₂ for those on vegetarian or vegan diets.

3. Monitoring Levels: Regular monitoring of Vitamin B₁₂ levels in patients on long-term metformin therapy is recommended to proactively address any deficiencies.

Conclusion

Patients on chronic metformin therapy should be aware of the potential risk of Vitamin B₁₂ deficiency and discuss with their healthcare provider about monitoring and supplementation options.

09/01/2026

Hello all!

Dr. Iswaraj Ramracheya, a distinguished endocrinologist and diabetologist, will be visiting Mauritius for a limited engagement of one week.

He will be available for consultations on Monday, 19 January, at Pharmacie Santé Plus in Goodlands as from 9:00 am.

Consultations will be conducted on a first-come, first-served basis.

07/01/2026