UIRRG

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Contactgegevens, kaart en routebeschrijving, contactformulier, openingstijden, diensten, beoordelingen, foto's, video's en aankondigingen van UIRRG, Health/Medical/ Pharmaceuticals, Yalelaan 50, Utrecht.

The Utrecht Inward Rectifier Research Group studies the function and regulation of ion channels involved in for example membrane excitability, insuline release and heart function.

27/04/2026

Together with my colleagues from Vienna and Nice we published a review on the development of inward rectifier current activators

Inwardly rectifying potassium (KIR) channels are essential regulators of membrane potential in excitable and non-excitable tissues. Although KIR channels exhibit a biophysical preference for potassiu...

20/10/2024

Just published. Our latest paper on the development of Kir2.1 activators.

Background and Purposes Reduced inward rectifier potassium channel (Kir2.1) functioning is associated with heart failure and may cause Andersen-Tawil Syndrome, among others characterized by ventricu...

04/05/2024

We published a review on developments in Kir2.1 pharmacological tools

The functioning of the human heart relies on complex electrical and communication systems that coordinate cardiac contractions and sustain rhythmicity. One of the key players contributing to this intricate system is the KIR2.1 potassium ion channel, which is encoded by the KCNJ2 gene. KIR2.1 channel...

11/03/2023

Our latest paper on the influence of chronic propafenon application on Kir2.1 expressing cells

Expression and activity of inwardly rectifying potassium (KIR) channels within the heart are strictly regulated. KIR channels have an important role in shaping cardiac action potentials, having a limited conductance at depolarized potentials but contributing to the final stage of repolarization and....

Adres

Yalelaan 50
Utrecht
3584CM

Website

https://www.umcutrecht.nl/en/Research/Researchers/van-der-Heyden-MAG

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