CombiBreed - English

CombiBreed - English Discover all about your pet with our genetic tests! From identifying breeds to disorders and traits.

This combination package is designed to provide essential insights into your dog’s genetic health, traits and diversity,...
05/06/2026

This combination package is designed to provide essential insights into your dog’s genetic health, traits and diversity, and includes DNA tests for a wide range of important diseases and/or traits. In addition, we also calculate the inbreeding coefficient (COI) and the percentage of heterozygosity in the DNA. The COI indicates the degree of inbreeding in the dog, whilst the heterozygosity percentage is a measure of individual genetic diversity.

This test is available under test code: H526.

X-linked Myotubular Myopathy (XLMTM) is a serious hereditary muscle disorder that has been identified in Maine C***s and...
03/06/2026

X-linked Myotubular Myopathy (XLMTM) is a serious hereditary muscle disorder that has been identified in Maine C***s and is caused by a mutation in the MTM1 gene. The condition affects muscle function and leads to progressive muscle weakness.
The first symptoms usually appear between the ages of 4 and 7 months. Affected cats may have difficulty walking and eating, lose muscle mass and find it harder to open their jaws. The condition is progressive and can seriously affect quality of life.

This test is available under test code: K478.

🎉 VHLGenetics celebrates its 40th anniversary! 🧬🎉For 40 years, we have been supporting pet owners and breeders with reli...
01/06/2026

🎉 VHLGenetics celebrates its 40th anniversary! 🧬🎉

For 40 years, we have been supporting pet owners and breeders with reliable diagnostics and DNA testing. It’s a milestone we’d love to celebrate with you.

That’s why, throughout June, you’ll receive a 10% discount on all orders placed in the CombiBreed webshop.

Use the code at checkout:
𝗔𝗡𝗡𝗜𝗩𝗘𝗥𝗦𝗔𝗥𝗬𝟰𝟬𝗖𝗕

We thank you for your trust over the past years. Together, we will continue to work towards healthy animals and responsible breeding.

Support the genetic health of your horse with our comprehensive DNA health package. This package provides an in-depth an...
29/05/2026

Support the genetic health of your horse with our comprehensive DNA health package. This package provides an in-depth analysis of your horse’s genetic profile and offers valuable insights into health conditions and inherited traits. Test for important hereditary disorders relevant to your breed, make informed breeding decisions and support responsible breeding for a healthier future.

This test can be ordered using test code: P307.

Intestinal Lipid Malabsorption (ILM) is an inherited metabolic disorder seen in Kelpies, caused by a mutation in the ACS...
27/05/2026

Intestinal Lipid Malabsorption (ILM) is an inherited metabolic disorder seen in Kelpies, caused by a mutation in the ACSL5 gene. This results in reduced intestinal absorption of dietary fats despite a normal to increased appetite.
Puppies are typically born appearing healthy but develop clinical signs within the first weeks to months of life. Common signs include reduced growth, leading to smaller size compared to littermates, as well as increased appetite and soft or fatty stools.

This new test can be ordered using test code: H097 and has been added to CombiBreed Kelpie H147.

2,8-Dihydroxyadenine (2,8-DHA) Urolithiasis is an inherited condition caused by a mutation in the APRT gene. This disrup...
25/05/2026

2,8-Dihydroxyadenine (2,8-DHA) Urolithiasis is an inherited condition caused by a mutation in the APRT gene. This disrupts the normal breakdown of purines, leading to the formation of crystals and urinary stones within the urinary tract.
The condition is inherited in an autosomal recessive manner and can occur in multiple dog breeds. Affected dogs may develop symptoms such as difficulty urinating, blood in the urine and recurrent urinary tract infections. In more severe cases, urinary blockages, kidney damage or kidney failure may occur.

This new test can be ordered using test code: H110.

Cerebellar Ataxia (CA) is an inherited neurological condition affecting the cerebellum, the part of the brain responsibl...
22/05/2026

Cerebellar Ataxia (CA) is an inherited neurological condition affecting the cerebellum, the part of the brain responsible for coordination and balance. In the Kelpie, this form is associated with a mutation in the LINGO3 gene, leading to impaired motor control.
The first signs usually appear at a young age. Affected dogs may show an uncoordinated gait, balance difficulties and tremors of the head or body. The condition can be progressive and may significantly impact quality of life.
This new test can be ordered using test code: H098 and has been added to CombiBreed Kelpie H147.

Our customer service team and laboratory will be closed over the Whitsun bank holiday. The swabs/hair bags for orders pl...
20/05/2026

Our customer service team and laboratory will be closed over the Whitsun bank holiday. The swabs/hair bags for orders placed before or on Monday 25 May will be dispatched on Tuesday 26 May. Results that would normally be processed on Monday will now be processed on Tuesday 26 May.

Hypertrophic cardiomyopathy (HCM) is a hereditary heart condition that has been reported in certain lines of Golden Retr...
18/05/2026

Hypertrophic cardiomyopathy (HCM) is a hereditary heart condition that has been reported in certain lines of Golden Retrievers. The condition is associated with a mutation in the TNNI3 gene, which is involved in the contraction of the heart muscle.

This condition causes the left ventricle in particular to thicken, reducing the heart’s pumping function. It is inherited in an autosomal recessive manner. Affected dogs may develop symptoms such as fatigue and exercise intolerance, and in severe cases, cardiac arrhythmias, collapse, heart failure or sudden death.

This new test can be ordered using test code: H116

Delayed Postoperative Haemorrhage (DEPOH) is a hereditary blood disorder that occurs primarily in Greyhounds and Scottis...
15/05/2026

Delayed Postoperative Haemorrhage (DEPOH) is a hereditary blood disorder that occurs primarily in Greyhounds and Scottish Deerhounds. The condition is caused by a mutation in the SERPINF2 gene, which means that blood clots form normally but are broken down more quickly.

DEPOH is inherited in an autosomal dominant manner with incomplete penetrance, meaning that not every dog with the mutation will develop symptoms. When symptoms do occur, they usually appear 1 to 4 days after surgery or injury and can range from mild bleeding to severe, sometimes life-threatening complications.

The new test can be ordered using test code: H099

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Wageningen
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