15/04/2024
PURPLE CORN EFFECTS ON ULTRAVIOLET RAYS
"PROTECTION AGAINST KERATINOCYTE DAMAGE"
❗️AGAINST CELL AGING
❗️CELLS DEATH AND
❗️CELLS INFLAMMATION
A clip from Study: CTTO
Poorahong, Watcharaporn; Innalak, Sukanda; Ungsurungsie, Watanapokasin, Ramida
Protective effect of purple corn silk extract against ultraviolet-B-induced cell damage in human keratinocyte cells.
Ultraviolet B (UVB) radiation is an important causative factor in skin damage, such as cell aging, death, and inflammation, because UVB easily infiltrates the epidermal layer of human keratinocyte cells.
A previous study found that the extract of purple corn silk inhibited keratinocyte damage in UVB-treated cells. In this context, Poorahong et al. investigated the protective effects of purple corn silk extract against inflammation in HaCaT cells induced by UVB. The purple corn silk extract attenuated NF-B activity by suppressing NF-κB nuclear translocation and protein expression.
Further, purple corn silk extract markedly decreased the phosphorylation of c-Jun and suppressed proinflammatory cytokines, in addition to iNOS and COX-2 levels, in UVB-treated cells. A novel purple corn extract, FB801, suppressed the expression of nuclear factor-κB proteins (NF-κB) in TNF-α-stimulated human keratinocyte (HaCaT) cells
Ultraviolet-B (UVB) could lead to inflammation and cell death induction. Purple corn silk (PCS), part of female flower of corn has multiple pharmacological properties. This investigation focused on determining the preventive effects of PCS extract on human keratinocyte HaCaT cell damage induced by UVB irradiation.
