Dr.Rana Saqlain Shoukat

Dr.Rana Saqlain Shoukat Doctor .Writer .Medical student .MBBS(MD)

๐Ÿ“‹ EMERGENCY CASE PRESENTATIONโ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”๐Ÿง‘โ€โš•๏ธ HISTORYโ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”๐Ÿ”น 48-year-old male๐Ÿ”น Chronic alcoholic๐Ÿ”น Brou...
02/06/2026

๐Ÿ“‹ EMERGENCY CASE PRESENTATION
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿง‘โ€โš•๏ธ HISTORY
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿ”น 48-year-old male
๐Ÿ”น Chronic alcoholic
๐Ÿ”น Brought to emergency department
๐Ÿ”น Acute presentation

๐Ÿ” EXAMINATION
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿ”ธ Delirium (acute confusional state)
๐Ÿ”ธ GCS 12 โ€” reduced consciousness
๐Ÿ”ธ Ataxia โ€” cerebellar/gait dysfunction
๐Ÿ”ธ Bilateral ophthalmoplegia โ€” extraocular muscle palsy

๐Ÿงช INVESTIGATIONS TO CONSIDER
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿ”ฌ Serum thiamine levels
๐Ÿ”ฌ Blood glucose (โš ๏ธ do NOT give glucose first!)
๐Ÿ”ฌ LFTs, ammonia level
๐Ÿ”ฌ FBC, electrolytes, magnesium
๐Ÿ”ฌ CT brain (to exclude bleed)
๐Ÿ”ฌ ABG
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”

โ“ What is the MOST LIKELY diagnosis and IMMEDIATE treatment?

A) Alcoholic cerebellar degeneration โ€” thiamine oral
B) Wernicke's encephalopathy โ€” IV thiamine (Pabrinex) 500 mg TDS before any glucose
C) Delirium tremens โ€” IV lorazepam + haloperidol
D) Hepatic encephalopathy โ€” lactulose + rifaximin
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿ’ฌ Drop your answer below! ๐Ÿ‘‡๐Ÿฝ
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”

LOW TESTOSTERONE: Signs You Shouldnโ€™t IgnoreShare this post to spread awareness and help others recognize the signs.    ...
02/06/2026

LOW TESTOSTERONE: Signs You Shouldnโ€™t Ignore

Share this post to spread awareness and help others recognize the signs.

Atorvastatin side-effects and management โฌ‡๏ธ
02/06/2026

Atorvastatin side-effects and management โฌ‡๏ธ

โš•๏ธ Clinical Vignette โ€“ Endocrinology & Pharmacologyโ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•๐Ÿฉบ HISTORY๐Ÿ”น 30-year-old woman๐Ÿ”น Post-partum โ€” 5 week...
30/05/2026

โš•๏ธ Clinical Vignette โ€“ Endocrinology & Pharmacology
โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•
๐Ÿฉบ HISTORY
๐Ÿ”น 30-year-old woman
๐Ÿ”น Post-partum โ€” 5 weeks
๐Ÿ”น Fever & rigors
๐Ÿ”น Sore throat
๐Ÿ”น Known case of thyrotoxicosis
๐Ÿ”น On Carbimazole since first trimester
โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•
๐Ÿ” EXAMINATION
๐Ÿ”น Acutely unwell / septic appearance
๐Ÿ”น Fever (hyperpyrexia)
๐Ÿ”น Throat โ€” inflamed / tonsillar involvement
๐Ÿ”น No localising signs of infection beyond oropharynx
โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•
๐Ÿงช INVESTIGATIONS
๐Ÿ”น WBC: 0.8 ร— 10โน/L โฌ‡๏ธ (severely low)
๐Ÿ”น Neutrophils: 0.1 ร— 10โน/L โฌ‡๏ธ (profound agranulocytosis)
๐Ÿ”น Blood cultures โ€” pending
๐Ÿ”น TFTs โ€” (thyroid function to be reviewed)
๐Ÿ”น CRP / ESR โ€” elevated
โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•
โ“ What is the most critical immediate action?

A) Increase carbimazole dose
B) Stop carbimazole immediately, admit to reverse isolation, take blood cultures, start broad-spectrum IV antibiotics, give G-CSF, notify endocrinology
C) Give prednisolone only
D) Restart propylthiouracil
โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•โ€•

๐Ÿง  ๐—–๐—Ÿ๐—œ๐—ก๐—œ๐—–๐—”๐—Ÿ ๐—–๐—”๐—ฆ๐—˜โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”๐Ÿ‘ฉ A 40-year-old woman presents with a lifelong bleeding tendency. Her father had prolonged...
30/05/2026

๐Ÿง  ๐—–๐—Ÿ๐—œ๐—ก๐—œ๐—–๐—”๐—Ÿ ๐—–๐—”๐—ฆ๐—˜
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿ‘ฉ A 40-year-old woman presents with a lifelong bleeding tendency. Her father had prolonged bleeding after a tooth extraction.
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿ“‹ ๐—›๐—œ๐—ฆ๐—ง๐—ข๐—ฅ๐—ฌ
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐ŸŸฃ Easy bruising โ€” spontaneous and recurrent
๐Ÿ”ด Menorrhagia โ€” heavy, prolonged menstrual bleeding
๐Ÿ’ฌ Father had prolonged post-extraction bleeding
๐Ÿ“… Symptoms suggest a lifelong, inherited condition
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿ”Ž ๐—˜๐—ซ๐—”๐— ๐—œ๐—ก๐—”๐—ง๐—œ๐—ข๐—ก
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿฉน Mucocutaneous bleeding pattern
๐Ÿšบ No haemarthrosis or deep muscle bleeds
๐Ÿ‘จโ€๐Ÿ‘ฉโ€๐Ÿ‘ง Family history consistent with autosomal inheritance
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿงช ๐—œ๐—ก๐—ฉ๐—˜๐—ฆ๐—ง๐—œ๐—š๐—”๐—ง๐—œ๐—ข๐—ก๐—ฆ
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐ŸŸข Platelet count โ€” ๐—ก๐—ผ๐—ฟ๐—บ๐—ฎ๐—น
๐Ÿ”ด Bleeding time โ€” ๐—ฃ๐—ฟ๐—ผ๐—น๐—ผ๐—ป๐—ด๐—ฒ๐—ฑ โฑ๏ธ (15 min)
๐ŸŸข PT โ€” ๐—ก๐—ผ๐—ฟ๐—บ๐—ฎ๐—น
๐Ÿ”ด APTT โ€” ๐—ฃ๐—ฟ๐—ผ๐—น๐—ผ๐—ป๐—ด๐—ฒ๐—ฑ โฑ๏ธ (50 sec)
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
โ“ ๐—ช๐—›๐—”๐—ง ๐—œ๐—ฆ ๐—ง๐—›๐—˜ ๐——๐—œ๐—”๐—š๐—ก๐—ข๐—ฆ๐—œ๐—ฆ?
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐—”) Haemophilia B
๐—•) Factor XI deficiency
๐—–) Von Willebrand disease (vWD)
๐——) Glanzmann's thrombasthenia
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”
๐Ÿ’ฌ Drop your answer below! Answer reveal coming soon ๐Ÿ‘‡
โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”โ”

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Acute Respiratory Distress syndrome
23/05/2026

Acute Respiratory Distress syndrome

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