03/06/2026
Most people are told colic is “normal.”
Just a phase, something babies grow out of.
But researchers studying the gut-brain axis are now asking a much bigger question:
What if colic is sometimes an early sign of immune and gut dysfunction?
A new long-term study following more than 1,200 children found infants with colic had significantly higher risks of food allergies later in childhood and adolescence and the findings were specific.
Researchers found infants with colic had:
👉 1.7x greater risk of food allergies in early childhood
👉 2.1x greater risk of peanut allergy in adolescence
👉 2.6x greater risk of tree nut allergy
👉 higher food-specific IgE sensitization
What’s important is that excessive crying alone was NOT associated with the same outcomes. Colic specifically showed the strongest relationship.
Researchers now believe infant colic may involve:
🦠 gut microbiome disruption
🦠 immune activation
🦠 increased gut permeability
🦠 inflammation affecting the gut-brain axis
And honestly… this is why I get frustrated when parents are dismissed instead of listened to.
Because researchers are increasingly studying colic as more than “just crying.”
They’re studying it as a possible early marker of immune and microbiome dysregulation.
This does NOT mean every baby with colic will develop allergies, but it does mean scientists are taking these early-life symptoms far more seriously than they used to.
And this is exactly why the first years of microbiome development matter so much.
Comment “GUT” and I’ll send you the free webinar where I explain what scientists are now discovering about infant gut health, eczema, allergies, and the microbiome 👇
References:
Switkowski KM et al.
“Associations of Colic and Excessive Crying in Infancy with Food Allergy Outcomes in Childhood and Adolescence.”
The Journal of Pediatrics. 2026.