09/02/2026
We get asked a lot: What is SPRAVATO® and how is it different from ketamine? So, let’s talk about it!
SPRAVATO® (esketamine) is an FDA-approved nasal spray for adults with treatment-resistant depression, and it’s related to ketamine, but not the same thing. Ketamine contains both parts of the ketamine molecule and can be given IV, IM, or sublingually. SPRAVATO® contains esketamine, just one part of that molecule, and is only administered as a nasal spray in certified treatment centers under a required monitoring program.
Both work on the brain’s glutamate system, but they’re regulated differently, and each may fit different needs. At Center for New Growth, we offer both so we can help you figure out which approach fits your goals, clinical needs, and insurance coverage.
Have more questions? Send us a message, or check out our SPRAVATO® webpage for more details. 🌱