Biochemical Nutrition

Biochemical Nutrition Integrative health care practice

A unique approach to health, addressing personal and scientific relationships with food by applying biochemistry, herbalism, nursing and care giving practices. This individual perspective provides a comprehensive understanding of others’ challenges to help develop a balanced lifestyle plan.

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07/22/2026

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Words of wisdom.
07/20/2026

Words of wisdom.

THE OLD FRIENDSHIP OF BLUEBERRIES AND SWEET FERN:

In the time before refrigeration, Ojibwe folks kept their blueberry harvest fresh by lining their birchbark storage containers with a plant called sweet fern (Comptonia peregrina) that often grows right alongside blueberry bushes!

The leaves of sweet fern produce a compound called gallic acid, which is a potent anti-microbial and keeps harmful bacteria like salmonella from growing on the berries.
It's name in the Ojibwe dialect is "giba`iganiminzh" meaning "it covers the berries" because of this usage and its contribution to keeping the precious staple food of minan (blueberries) fresh!

I don't use a birchbark container but I do pop a few sprigs of sweet fern into my gathering bag when out picking or storing berries to remember and utilize the gifts of this wonderful plant!

(Sweet fern can also be used as a medicinal tea to help the intestines and colon. Rub it on your skin or add to a fire and the smoke will help keep away mosquitos and horse flies--in addition to smelling lovely!)

07/11/2026
05/15/2026

What are selenoproteins? What is the link between urinary tract infections and type 2 diabetes? 🧐

This week's ASM Journal Highlights has the answers to these questions and more! 😄

🦠Enterococcus faecalis not only antagonizes Pseudomonas aeruginosa growth under iron limitation, but also induces a unique transcriptional profile, enhancing P. aeruginosa survival during antibiotic challenge. Learn more in : https://asm.social/2Wr

🥼Fascioliasis is a zoonotic trematode infection. A new case report outlines the recovery of an adult Fasciola from the biliary tree in a patient presenting with possible ascending cholangitis and acute acalculous cholecystitis. : https://asm.social/2Wo

🔬Using a mouse model, researchers show that both hyperglucosuria and type 2 diabetes promote the onset of severe UTI, and that systemic dissemination of urinary tract origin is likely caused by altered neutrophil trafficking to the bladder. : https://asm.social/2Wp

🧬Selenoproteins, a unique class of proteins critical for cellular antioxidant defense, are characterized by the incorporation of selenocysteine (Sec) in their active sites. In : the molecular mechanisms underlying Sec biosynthesis and incorporation: https://asm.social/2Ws

🖥️New in : adaptive sampling improves metagenomic yield and characterization of the chicken gut microbiome. The method allows for depletion of host DNA and improvement of microbial data yield without requiring additional time and resources: https://asm.social/2Wq

For more new research published in , visit https://asm.social/2Wn

And stay tuned for the next !

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04/11/2026

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🌿 SPRING TONICS🥂 A Spirited History 🌿 🫖 🍸
"Traditionally, tonics were seen as medicinal substances taken to give a feeling of well-being or vigor. But anything invigorating physically, mentally, or morally could now be said to be a tonic. A kind greeting can be a tonic. So can nature, gardening, art, and music. All refresh the human spirit. Health. The word comes from the Old English for “whole,” as in the state of your whole being—mind, body, and spirit. The old herbalists used herbs to address the root causes of illness; their garden botanicals were a prescriptive and dietary means to balance the whole system and maintain good health. In contrast, much of the focus of modern Western medicine has been on suppressing symptoms, with pills. But household botanists understand that the foods we eat and the tonics we sip support our overall health and well-being, before we need a capsule. I do my best to stay well by finding ways to support my health from my garden. The tonic of fresh air and exercise, the tonic of working in my garden, the tonic I sip to refresh my spirits, the spring tonic that renews after a long winter, or the gin and tonic I sip on a sultry summer night.

Cultures with limited sources of fresh food in winter often have traditions regarding the restorative and curative powers of spring’s earliest plants. Spring tonics were seen as a means to restore vigor after a long winter’s diet of mostly preserved and less vital foods; they could be as simple as eating a particular dish of greens, sipping on an herbal tea, or partaking in a wide range of blended botanicals that were used to increase stamina, keep the body regular, or invigorate mind and body, as some use coffee or chocolate today.

As a gardener, my spirits soar when I harvest the first greens of spring. I know that I am imbibing all the vibrant life force and energy stored beneath the ground through winter, whether by adding chives to cheese or making a rhubarb cobbler or lovage soup. It’s wonderful to stir your senses with an early spring salad of violets, arugula, and sorrel cultivated in your own backyard.
First Nations and early settlers also delighted in eating the first “knots and buds” (tender leaves, buds, and flowers) of spring. Much as we do today, they found great satisfaction and rejuvenation consuming these vital outgrowths of warming earth and sun. They drank sassafras tea, ate beets and spinach to improve the blood, chewed on parsley for the vibrant green flavor that chlorophyll imparts. These settlers were firm believers in the tonifying effects of spring greens, which were said to stimulate digestion, cure scurvy, combat rheumatism, and ease constipation after a long cold winter of preserved foods and relative inactivity.

One beloved spring edible is the ramp (Allium tricoccum). First Nations and early settlers valued these ephemeral native leeks as both a spring tonic and a culinary onion. Like garlic, these members of the onion family are used to improve health, cleanse blood, and protect people from illness. They have scientifically proven antiseptic and expectorant properties that can assist with colds and virus. Research also shows that ramps supply vitamin C, minerals, and allicin, which has antimicrobial and antithrombotic (blood-thinning) properties— all attributes that make it an enviable tonic for early spring.

Because the earth needs the tonic of co-conspirators too, I have learned to cultivate both ramps and fiddleheads in the woods and gardens around my home, doing my part to strengthen, instead of deplete, wild populations. But if these native plants are scarce, my Italian grandmother’s simple dish of dandelion greens is a spring tonic fit for any table. They are known as an edible liver and kidney tonic, and there are always more than enough to go around.

Not all tonics, however, were homegrown or foraged; many were created as pharmaceuticals. These apothecary tonics and bitters, ubiquitous from Eurasia to the New World, reached their pinnacle in the 19th century, as people fell out of sync with the tonic of nature and found themselves working in cities and factories. They were intended to provide vigor for weary workers and aging bodies. Ginseng (Panax quinquefolius), sarsaparilla (Aralia nudicaulis), and their Asian relatives were used as male tonics to increase libido. Blue cohosh (Caulophyllum thalictroides) and motherwort (Leonurus cardiaca) were used as female tonics for women’s health; and nerve tonics made with nervine herbs (skullcap, chamomile, valerian root, hops, lemon balm, St. John’s wort) were tinctured and popularly prescribed to women with melancholic and choleric tendencies— typically depression or boldness, no doubt brought on by being an intelligent, spirited, or sexual woman in the buttoned-up Victorian era.

Their male counterparts, who were generally freer to carouse, often self-prescribed with alcohol. In the bars they frequented, a new generation of cocktails was made using bitters from mugwort, passionflower, wormwood, angostura bark, orange peel, and other botanicals—tonics intended to support liver and kidney functions that were undermined by the consumption of alcohol in the first place.

As the temperance movement suppressed public consumption, producers found legal loopholes in the historic method for tincturing herbs in alcohol to preserve them. Mass production, along with new means of advertising and delivery, helped a generation of Victorians to disguise booze as a botanical wonder drug. In the process, they profited from bottling swigable doses of alcohol-based tonics that could be purchased without stigma. Unfortunately, many of these patent medicines and cure-all tonics became vehicles for delivering addictive doses of alcohol and narcotics to unsuspecting consumers and families.

Meanwhile, overseas, tonics were taking another turn. Quinine powder prescribed to combat scurvy was so bitter that British officials stationed in India and other tropical outposts mixed the powder with soda and sugar. By 1858 the first commercial tonic water came to be a staple medicinal—with an alcohol chaser. That pairing was the gin and tonic. And for those drawn to the temperance movement, a new generation of syrupy tonics like sarsaparilla, root beer, and cola were designed to appeal to wholesome industrial workers while temporarily jacking them up on co***ne, o***m, or caffeine. Feckless producers were eventually reined in: the coke in Coke was removed, the lithium in 7-Up was struck down, and only the fizzy, sugary pablum remained. For better or worse, all these shady tonics helped usher in the age of modern medicine and medical reform.

Unfortunately for gardeners and domestic botanists, the baby was thrown out with the bathwater, and for almost a century, herbs and herbalism were demeaned as the stuff of old wives’ tales—until herbs were finally analyzed scientifically for medicinal use. I could say I use caffeine like a tonic at times. Certainly, the early Coke ads promoted it that way. But mainly I see tonics as any refreshment from my garden or spice drawers that supports my well-being, whether that means breathing in the scent of a rose, sipping a cup of restorative ginger tea, or drinking beet kvass.

Any week, in every season, is improved by tonics. Friday night I was uplifted by some spruce beer and an herbal gruit at my local brewery. Next morning’s tonic evolved from a gift of frozen homemade wild grape juice: I brought the thawing juice to a high heat and turned it into an oxymel, simmering it down with cider vinegar from a neighbor’s orchard and local honey. Suddenly, in the middle of winter, I was sipping small doses of sweet, piquant, late summer from a spoon, nectar from the vine, and a tonic that tonified my gut; with the addition of vinegar, it acted like a roto-rooter for my arteries and provided me with a much-needed megadose of vitamin C. Saturday night’s tonic came in the form of a Sazerac (said to be the oldest cocktail in America) made with wormwood absinthe and Peychaud’s Bitters. Sunday was a good day for a dose of lemon balm in the teapot, and Monday called for ginseng to wake mind and body. Tuesday brought sunshine, a tonic all its own. Wednesday, it took a strong dose of coffee to bring me back into the world, and some kombucha, like a probiotic version of the grape oxymel, accompanied lunch. Thursday, I drank a Moxie with my sandwich to get through the afternoon. In New England, we still call soda tonic. Perhaps, as the old herbalists would say, it’s just in our blood.

*(From my book - https://www.amazon.com/Heirloom-Gardener-Traditional-Plants-Skills/dp/1604699930 Happy & Healthy Spring! The Heirloom Gardener - John Forti

Epigenetics
03/01/2026

Epigenetics

Epigenetics researchers at the Institut Pasteur in Paris and INSERM have completed the most definitive human study of transgenerational epigenetic inheritance ever conducted — following three generations of Holocaust survivor families, Cambodian genocide survivor families, and control populations across 25 years — finding specific, reproducible methylation changes in stress-response genes (particularly the FKBP5 and NR3C1 glucocorticoid receptor genes) that are present in trauma survivors, transmitted to their biological children, and detectable in grandchildren who never experienced trauma themselves. Emotional pain leaves molecular scars. Those scars are heritable. 🧬
The mechanism — once considered impossible in mammals because the genetic dogma held that acquired characteristics cannot be inherited — operates through the germline epigenome. During the formation of s***m and eggs, the genome undergoes near-complete epigenetic reprogramming to remove parental marks. "Near-complete" is the operative word. Certain loci, including stress-response gene promoters, resist this reprogramming when the parent's stress exposure has been sufficiently severe and prolonged, maintaining their trauma-induced methylation patterns through the reprogramming process and passing them to the offspring's genome. The trauma experience writes itself into the reproductive cells.
The clinical implications are profound and already actionable. Children and grandchildren of trauma survivors show elevated baseline cortisol levels, altered HPA axis responsiveness, and increased risk of PTSD, anxiety, and depression — not because of how they were raised, but because of how their grandparents suffered. Understanding this mechanism means targeted epigenetic therapies could potentially reverse inherited stress marks, liberating future generations from trauma they never personally experienced.
The Pasteur team is now working with EMDR and methylation-targeting drug combinations. This is no longer metaphor — the inheritance of trauma is molecular, measurable, and potentially reversible.
Source: Institut Pasteur Paris / INSERM, Nature Reviews Genetics 2025

Proteomics used to detect ‘natural medicinals used in global trade’, demonstrating significant historical experimentatio...
12/03/2025

Proteomics used to detect ‘natural medicinals used in global trade’, demonstrating significant historical experimentation.

Analyses of German medical manuals from 1531 reveal what ingredients those who handled the books used

11/08/2025

James D. Watson, the brilliant but controversial American biologist whose 1953 discovery of the structure of DNA ushered in the age of genetics and provided the foundation for the biotechnology revolution of the late 20th century, died at age 97. https://reut.rs/4ouo4tO

10/25/2025

This , we celebrate a milestone in science and humanity. ASM is proud to name the University of Pittsburgh a Milestones in Microbiology site—honoring Jonas Salk and his team at the Virus Research Laboratory (1948–1955), where they developed the world’s first safe and effective polio vaccine. Licensed in 1955, the vaccine reduced paralytic polio in the U.S. by 96% within a few years and changed the course of global health.

At today’s celebration and ceremony, ASM officially recognized the University’s designation and highlighted the newly opened Salk Legacy Exhibit, which chronicles the research and innovation that led to this historic breakthrough.

📸 ASM Archivist Colleen Puterbaugh is pictured at the Salk Legacy Exhibit next to an iron lung.

Learn more: https://asm.social/2F2

Pitt Public Health

Historically plant based medicine!
09/25/2025

Historically plant based medicine!

📌 WORLD PHARMACIST DAY
World Pharmacist Day is a special occasion to recognize the vital role pharmacists play in advancing global health and patient well-being(see the generated image above). Their commitment to safe medicine use, expert advice, and compassionate care helps communities lead healthier lives every day(see the generated image above). On this day, appreciation is extended to all pharmacists for their dedication, professionalism, and ongoing contribution to public health(see the generated image above).

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