09/08/2026
A translational study connected several evidence layers: greater measured biofilm abundance in symptomatic tissue samples, higher 10-HOME levels in a small tissue subset, Th1 polarization in laboratory exposed human cells, and selected immune findings plus fatigue-like behavior in mice. That chain is biologically interesting and testable. It is not final proof that one pathway explains every person, that experimental mouse exposure matches human exposure, or that blocking 10-HOME would improve symptoms. It does not establish a diagnostic test or treatment. Education only. Discuss personal decisions with your provider. Study: https://doi.org/10.1172/JCI165644 Please share this with someone who values careful research translation.