Nyree Penn- REM Sleep & Brain Health Expert

05/21/2026

You may be sleeping… but is your brain actually restoring? 🧠🌙

Most people think sleep is simply about “getting hours.”

But true health depends on something deeper:
NeuroRestorative Sleep™.

At 🌙 NSOMNIA Sleep™, we focus on what happens INSIDE the brain during sleep:
⚡ Neurotransmitter balance
⚡ REM sleep integrity
⚡ Brain restoration
⚡ Memory & emotional regulation
⚡ Neurological recovery

Because sedation is not the same as restoration.

If you wake up:
❌ exhausted
❌ mentally foggy
❌ anxious
❌ dependent on sleep medications
❌ emotionally drained

…your brain may not be achieving restorative sleep.

Your body can be unconscious while your brain remains unrestored.

That’s why we created:
🧠 NSDx™ — NeuroRestorative Sleep Assessment
to evaluate whether your brain is truly recovering during sleep.

This is the future of sleep medicine.

Not sedation. Restoration.™

📍Miami, Florida
🌐 Visit the link in bio to schedule your NeuroRestorative Sleep Assessment or take the NeuroSleep Quiz.



https://www.instagram.com/reel/DYlapsouPBU/?igsh=M2c0Z3lkcGVjNWY2

05/19/2026

🌙 What if the problem isn’t whether you sleep… but whether your brain actually restores?

Millions of people undergo “normal” sleep studies every year — yet still wake up exhausted, foggy, anxious, and unrefreshed.

Traditional sleep studies (PSG) measure:
✔️ Breathing
✔️ Oxygen levels
✔️ Movement
✔️ Sleep stages

But they may not fully assess whether the brain achieves a truly restorative state.

At 🌙 NSOMNIA Sleep , we are exploring a different question:

👉 Can the brain enter, maintain, and recover from restorative neurophysiologic states?

Our innovative sleep therapy— the NSOMNIA NeuroRestorative Assessment (NSDx) — uses controlled neurophysiologic monitoring under monitored anesthesia care to evaluate brain-state stability, recovery dynamics, and restorative function in ways conventional testing may miss.

Early observational findings suggest distinct neurophysiologic “sleep endotypes,” including:
• Hyperarousal
• Transition instability
• Restorative failure
• Circadian mismatch

These patterns may help explain why two patients with identical sleep studies can experience completely different symptoms.

We are also investigating potential links to the brain’s glymphatic system — the nighttime clearance pathway associated with removing metabolic waste and inflammatory proteins during deep restorative states.

If validated through larger studies, this approach could help:
🔹 Improve insomnia subtyping
🔹 Personalize treatment strategies
🔹 Identify objective biomarkers of restorative dysfunction
🔹 Advance neuroscience understanding of sleep restoration and consciousness

🌙 NSDx raises an important possibility:

➡️ “Normal sleep” may not always mean restorative sleep.

The future of sleep medicine may depend not only on measuring sleep itself — but on measuring how the brain restores.

05/17/2026

🌟Honored to present at the 2026 Florida Society of Anesthesiologists Annual Meeting! !

I’ll be sharing 🌙 NSOMNIA Sleep research on EEG-based neurophysiologic phenotypes during monitored anesthesia care by presenting my digital poster:

A Controlled EEG-Based NeuroRestorative Assessment Under Monitored Anesthesia Care: Identification of Neurophysiologic Phenotypes and Mechanistically Informed Endotypes (Read Abstract Here: https://www.fsahq.org/abstract-reply-form/?id=a0c9b8719e357cc496747e6773069cf3 )

Catch my virtual poster:
📅 June 12, 2026
⏰ 12:00-12:30 PM
📌 Digital Poster Session 4, DP29

Excited for the opportunity to contribute to advancing anesthesia care with the Florida Society of Anesthesiologists and American of Anesthesiologists® See you there! 🌟

05/04/2026

✨ Meet the woman who discovered why so many people can’t sleep—and how to restore it.

Nyree Penn, MHSc, CAA, spent over 15 years in clinical anesthesia and brain monitoring, working in an environment where the brain can be taken in and out of unconsciousness… on demand.

But what she uncovered changed everything:

We know how to sedate the brain for surgeries—
But we haven’t mastered how to restore natural sleep.

That insight led her to a critical, overlooked mechanism:
adenosine—the brain’s sleep pressure system.

When it’s working, sleep happens.
When it’s disrupted, nothing else works.

Not routines.
Not supplements.
Not sleep hygiene.

So she built a new approach.

By combining brain science with her clinical expertise in anesthesia, she pioneered:

🌙 NSOMNIA Sleep: NeuroRestorative Sleep
Including the first-of-its-kind anesthesia-induced sleep therapy

A breakthrough designed to restore sleep at its source—the brain itself.

This isn’t about managing sleep problems.

It’s about restoring the brain. And it’s changing everything.

🌙NSOMNIA Sleep "Not Sedation-Restoration"

www.nsomniasleep.com

03/18/2026

🩷 Why does sleep change throughout a woman’s life?

From puberty to pregnancy to perimenopause and menopause—most women are told it’s “just hormones.”

But that’s only part of the story.

In this episode, we explore the deeper neurobiology of sleep—how hormones AND neurotransmitters shape sleep quality, brain recovery, and overall health across every stage of a woman’s life.

💤 In this episode, you’ll learn:
• Why women’s sleep evolves across generations
• The critical role of neurotransmitters in sleep disruption
• How REM sleep impacts mood, metabolism, and brain function
• Why traditional approaches to sleep are failing women
• What true sleep restoration actually means

This is not about sedation.
This is about restoring the brain.

🌙 NSOMNIA Sleep Health
Not Sedation. Restoration.

🎧 Watch now:

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”Welcome back to Sleep Reimagined, where we explore what it truly means...

03/09/2026

✨ Excited to speak at the AAAA 2026 Annual Conference!

🗓 Thursday, April 9
🕐 1–2 PM
📍 Plaza Ballroom CF

CME Lecture:
The Dynamic Duo of Anesthesia and EEG

I’ll be sharing how EEG is transforming brain monitoring in anesthesia and expanding its applications beyond the operating room—bridging anesthesia, neuroscience, and sleep medicine.

Hope to see you there!

01/13/2026

🛑 Stop saying you “slept too much.”
You didn’t overdose on REM. 😅

Deep sleep + REM = repair + memory + emotional reset.
If you slept 8–10 hours and feel worse, it’s usually not “too much sleep”… it’s:
• sleep debt payback
• poor sleep efficiency (lots of time in bed ≠ lots of real sleep)
• circadian misalignment
• a hidden disruptor (stress, apnea, meds, mood, inflammation)

🧠 Adenosine is your brain’s sleep-pressure signal—built up from energy use (ATP) while you’re awake.
REM Sleep is supposed to release that pressure so you wake up restored.

So if you wake up tired after “a full night,” the question isn’t more sleep…
it’s better sleep.

Comment “9” if 9 hours makes you feel more exhausted than 7. 👇

🎤 Catch the full episode on Spotify: https://open.spotify.com/show/59f0Zn74llqc1PXBvM4Fzp?si=EtsZ8BwgQE2d9eXqpB9FTA

01/02/2026

🎥 New Episode: Sleep Reimagined- Is Technology Helping or Hijacking Your Sleep? Exploring Digital Disruptors and Better Rest

Is technology actually helping your sleep…
or quietly sabotaging your brain at night?

In this episode of Sleep Reimagined, I take on a modern sleep dilemma most people don’t realize is keeping them wired, tired, and unrested.

📱 From late-night scrolling
⌚ To sleep trackers and “perfect sleep scores”
📊 To smart devices that promise rest but often deliver anxiety

We dive into the real brain science behind tech-triggered insomnia, including:
• How blue light suppresses melatonin
• Why dopamine depletion keeps your brain “on” even when you’re exhausted
• How wearables can fuel orthosomnia — the obsession with perfect sleep data
• Why you can feel tired even after a full night in bed

But it’s not all bad news.

I also share how to use technology mindfully, interpret sleep data without stress, and reclaim truly restorative REM sleep — without letting devices rule your bedroom.

If you’ve ever:
✔️ Doom-scrolled before bed
✔️ Woken up tired despite “good” sleep stats
✔️ Felt anxious about your sleep app

This conversation is for you.

🧠 Sleep isn’t rest. It’s brain repair.
Let’s rethink our relationship with technology — and rediscover what it means to really rest.

“Disclaimer: Informational only. Not medical advice. Consult your doctor for guidance.”Welcome back to Sleep Reimagined, where we dive into the science, stor...

01/01/2026

🎉 HAPPY NEW YEAR!! 🥂We just released our new episode on Spotify. Please like and share 🤩

https://open.spotify.com/show/59f0Zn74llqc1PXBvM4Fzp?si=u7k29ZLDS0Op6ur3EKoAng

Podcast · TopHealth Media · Unlocking the secret of wellness through the transformative power of sleep.Explore the depths of sleep and its profound impact on health with Nyree Penn, MHSc., CAA. "Sleep Reimagined" reveals how reclaiming restful nights can redefine your days and unlock a life of tru...