06/02/2023
Why does s*x or**sm produce a smooth muscle contraction period at about 0.8 seconds/cycle for the male and female g***d, the average heart rate! The Cellular Membrane Depolarization Oscillator makes it like that.
S*x or**sm is a smooth muscle contraction of the human g***ds or pelvis in nature. Mechanisms of pelvic/g***d smooth muscles, s*x or**sm, can be generated in the following 3 approaches according to this video: https://www.youtube.com/watch?v=428gDBSl5-A :
(1). myogenic mechanism (depolarization of calcium ion channel by nervous stimulation or stretch). Phasic smooth muscle cells, or SMCs , (such as vas deferens, uterus and bladder) rely on membrane depolarization to drive Ca2+ influx across the plasma membrane for contraction. This depolarization can be induced by neurotransmitters or through the operation of a membrane oscillator, likely at the heart rate of about 0.8 seconds, that is around 70-75 times per minutes. Many tonic smooth muscle cells (SMCs) (vascular, airway and corpus cavernosum) are driven by a cytosolic Ca2+ oscillator that generates periodic pulses of Ca2+. A similar oscillator is present in pacemaker cells such as the interstitial cells of Cajal (ICCs) and atypical SMCs that control other tonic SMCs (gastrointestinal, urethra, ureter). The changes in membrane potential induced by these cytosolic oscillators does not drive contraction directly but it functions to couple together individual oscillators to provide the synchronization that is a characteristic feature of many tonic SMCs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652144/ ; ttps://en.wikipedia.org/wiki/Myogenic_mechanism #:~:text=The%20myogenic%20mechanism%20is%20how,stimulus%20such%20as%20nerve%20innervation ;
(2) catecholamines - Under the s*xual arousal, the dopaminergic nervous system stimulates the stress axis - the hypothalamus-pituitary-adrenal axis, where the hypothalamus and adrenal medular convert into norepinephrine and then epinpehrine, and the hypothalamus-pituitary axis alternatively and pulsely releases oxytocin, prolactin and vasopressin. Under the alternative effects of prolactin and oxytocin, the neurohormone epinephrine is binded into the alpha- and beta- adregernic receptors of the sympathetic nervous system, respectively, where the alpha receptor induces contraction while the beta relaxes it.https://en.wikipedia.org/wiki/Catecholamine ;
(3) Human vasopressin, also called antidiuretic hormone (ADH), released by the posterior pituitary to the bloodstream, as well as from the hypothalamus to the brain, which not only induced or**smic contraction, but also play an important role in social behavior, s*xual motivation and pair bonding, and maternal responses in stress. This can explain s*x or**sm is an emotional super glue. https://en.wikipedia.org/wiki/Vasopressin
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